Results
repositories = "The Univ. of Birmingham: The ePrints Archive"
A systematic review of the effectiveness of adalimumab, etanercept and infliximab for the treatment of rheumatoid arthritis in adults and an economic evaluation of their cost-effectiveness
Author(s) :
Chen, Y-F.
,
Jobanputra, Paresh
,
Barton, Pelham
,
Jowett, S.M.
,
Bryan, S.
,
Clark, Wendy
,
Fry-Smith, A.
,
Burls, Amanda
Description :
Objectives: This report reviews the clinical effectiveness and cost-effectiveness of adalimumab, etanercept and infliximab, agents that inhibit tumour necrosis factor-a (TNF-a), when used in the treatment of rheumatoid arthritis (RA) in adults.
Data sources: Electronic databases were searched up ...
Repository :
The Univ. of Birmingham: The ePrints Archive
Language(s) :
Undetermined
Direct observations of the kinetics of migrating T-cells suggest active retention by endothelial cells with continual bidirectional migration.
Author(s) :
McGettrick, Helen M.
,
Hunter, Kirsty
,
Moss, Paul A.
,
Buckley, Christopher D.
,
Rainger, G. Ed
,
Nash, Gerard B.
Description :
The kinetics and regulatory mechanisms of T-cell migration through endothelium have not been fully defined. In experimental filter-based assays in vitro, transmigration of lymphocytes takes hours, compared to minutes in vivo. We cultured endothelial cell (EC) monolayers on filters, solid substrates ...
Repository :
The Univ. of Birmingham: The ePrints Archive
Language(s) :
Undetermined
Increased hydrogen production by Escherichia coli strain HD701 in comparison with the wild-type parent strain MC4100
Description :
Hydrogen production by Escherichia coli is mediated by the formate hydrogenlyase (FHL) complex. E. coli strain HD701 cannot synthesize the FHL complex repressor, Hyc A. Consequently, it has an up-regulated FHL system and can, therefore, evolve hydrogen at a greater rate than its parental wild type, ...
Repository :
The Univ. of Birmingham: The ePrints Archive
Language(s) :
English
Towards an integrated system for bio-energy: hydrogen production by Escherichia coli and use of palladium-coated waste cells for electricity generation in a fuel cell
Description :
Escherichia coli strains MC4100 (parent)
and a mutant strain derived from this (IC007) were
evaluated for their ability to produce H2 and organic
acids (OAs) via fermentation. Following growth,
each strain was coated with Pd(0) via bioreduction of
Pd(II). Dried, sintered Pd-biomaterials (‘Bio-Pd’)
w...
Repository :
The Univ. of Birmingham: The ePrints Archive
Language(s) :
Undetermined
A two-stage, two-organism process for biohydrogen from glucose
Description :
H2 can potentially be produced in a two-stage biological process: the fermentation of glucose by Escherichia coli HD701 and the photofermentation of the residual medium by Rhodobacter sphaeroides O.U. 001. In a typical batch fermentation, E. coli consumed glucose and produced H2, organic end-product...
Repository :
The Univ. of Birmingham: The ePrints Archive
Language(s) :
Undetermined
Interaction Issues in Computer Aided Semantic Annotation of Multimedia
Author(s) :
Bowers, Chris P.
,
Byrne, Will
,
Melhuish, Jonathan
,
Lonsdale, Peter
,
Creed, Chris
,
Pinder, Charlie
,
Beale, Russell
Description :
The CASAM project aims to provide a tool for more efficient and effective annotation of multimedia documents through collaboration between a user and a system performing an automated analysis of the media content. A critical part of the project is to develop a user interface which best supports both...
Repository :
The Univ. of Birmingham: The ePrints Archive
Language(s) :
Undetermined
Dissociation dynamics of fluorinated ethene cations: from time bombs on a molecular level to double-regime dissociators
Description :
The dissociative photoionization mechanism of internal energy selected C\(_2\)H\(_3\)F\(^+\), 1,1-C\(_2\)H\(_2\)F\(_2^+\), C\(_2\)HF\(_3^+\) and C\(_2\)F\(_4^+\) cations have been studied in the 13−20 eV photon energy range using imaging photoelectron photoion coincidence spectroscopy. Five predomin...
Repository :
The Univ. of Birmingham: The ePrints Archive
Language(s) :
English
Integrating dark and light biohydrogen production strategies: towards the hydrogen economy
Description :
Biological methods of hydrogen production are preferable to chemical methods because of the possibility to use sunlight, CO2 and organic wastes as substrates for environmentally benign conversions, under moderate conditions. By combining different microorganisms with different capabilities, the indi...
Repository :
The Univ. of Birmingham: The ePrints Archive
Language(s) :
Undetermined
Biomass-supported catalysts on Desulfovibrio desulfuricans and Rhodobacter sphaeroides
Description :
A Rhodobacter sphaeroides-supported dried, ground palladium catalyst (‘‘Rs-Pd(0)’’) was compared with a Desulfovibrio desulfuricans-supported catalyst (‘‘Dd-Pd(0)’’)and with unsupported palladium metal particles made by reduction under H2 (‘‘Chem-Pd(0)’’). Cell surface-located clusters of Pd(0) nano...
Repository :
The Univ. of Birmingham: The ePrints Archive
Language(s) :
Undetermined
Deletion of a mycobacterial gene encoding a reductase leads to an altered cell wall containing β-oxo-mycolic acid analogues, and the accumulation of longchain ketones related to mycolic acids.
Author(s) :
Bhatt, Apoorva
,
Brown, Alistair K.
,
Singh, Albel
,
Minnikin, David E
,
Besra, Gurdyal S
Description :
Mycolic acids are essential components of the mycobacterial cell wall. In this study we show that a gene encoding a reductase involved in the final step of mycolic acid biosynthesis can be deleted in Mycobacterium smegmatis without affecting cell viability. Deletion of MSMEG4722 (ortholog of Mycobac...
Repository :
The Univ. of Birmingham: The ePrints Archive
Language(s) :
Undetermined