Results
repositories = "ECNIS Repository (Environmental Cancer Risk, Nutrition and Individual Susceptibility Repository)"
Circadian rhythms and chemical carcinogenesis: Potential link. An overview.
Description :
Circadian rhythm is an integral and not replaceable part of the organism's homeostasis. Its signalling is multidimensional, overlooking global networks such as chromatin remodelling, cell cycle, DNA damage and repair as well as nuclear receptors function. Understanding its global networking will all...
Repository :
ECNIS Repository (Environmental Cancer Risk, Nutrition and Individual Susceptibility Repository)
Language(s) :
English
Ethics and data protection in human biomarker studies.
Description :
Human biomarker studies in environmental health are essential tools to study the relationship between health and environment. The development of relevant research potential and the setup of bio-monitoring surveys should ultimately lead to a better understanding and prevention of environmentally indu...
Repository :
ECNIS Repository (Environmental Cancer Risk, Nutrition and Individual Susceptibility Repository)
Language(s) :
English
3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone, induces biotransformation enzymes in rat kidney and lung.
Author(s) :
Stiborova, Marie
,
Dracinska, Helena
,
Martinkova, Marketa
,
Mizerovska, Jana
,
Hudecek, Jiri
,
Hodek, Petr
,
Liberda, Jiri
Description :
3-aminobenzanthrone (3-ABA) is the metabolite of the carcinogenic air pollutant 3-nitrobenzanthrone (3-NBA). 3-ABA was investigated for its ability to induce cytochrome P450 1A1 (CYP1A1) and NAD(P)H:quinone oxidoreductase (NQO1) in kidney and lung of rats, and for the influence of such induction on ...
Repository :
ECNIS Repository (Environmental Cancer Risk, Nutrition and Individual Susceptibility Repository)
Language(s) :
English
3-Nitrobenzanthrone and 3-aminobenzanthrone induce DNA damage and cell signalling in Hepa1c1c7 cells.
Author(s) :
Landvik, N.E.
,
Arlt, V.M.
,
Nagy, E.
,
Solhaug, A.
,
Tekpli, X.
,
Schmeiser, H.H.
,
Refsnes, M.
,
Phillips, D.H.
,
Lagadic-Gossmann, D.
Description :
3-Nitrobenzanthrone (3-NBA) is a mutagenic and carcinogenic environmental pollutant found in diesel exhaust and urban air pollution. In the present work we have characterised the effects of 3-NBA and its metabolite 3-aminobenzanthrone (3-ABA) on cell death and cytokine release in mouse hepatoma Hepa...
Repository :
ECNIS Repository (Environmental Cancer Risk, Nutrition and Individual Susceptibility Repository)
Language(s) :
English
A commentary on "Urea, the most abundant component in urine, cross-reacts with a commercial 8-OH-dG ELISA kit and contributes to overestimation of urinary 8-OH-dG". What is ELISA detecting?
Author(s) :
Cooke, Marcus S.
Description :
MSC is a partner of ECNIS (Environmental Cancer Risk, Nutrition
and Individual Susceptibility), a network of excellence operating
within the European Union 6th Framework Program, Priority 5:"Food
Quality and Safety" (Contract No 513943). Research in MSC's
laboratory is supported by the ECNIS, World ...
Repository :
ECNIS Repository (Environmental Cancer Risk, Nutrition and Individual Susceptibility Repository)
Language(s) :
English
A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer.
Author(s) :
Kiemeney, Lambertus A.
,
Sulem, Patrick
,
Besenbacher, Soren
,
Vermeulen, Sita H.
,
Sigurdsson, Asgeir
,
Thorleifsson, Gudmar
Description :
Previously, we reported germline DNA variants associated with risk of urinary bladder cancer (UBC) in Dutch and Icelandic subjects. Here we expanded the Icelandic sample set and tested the top 20 markers from the combined analysis in several European case-control sample sets, with a total of 4,739 c...
Repository :
ECNIS Repository (Environmental Cancer Risk, Nutrition and Individual Susceptibility Repository)
Language(s) :
English
A field synopsis on low-penetrance variants in DNA repair genes and cancer susceptibility.
Author(s) :
Vineis, Paolo
,
Manuguerra, Maurizio
,
Kavvoura, Fotini K.
,
Guarrera, Simonetta
,
Allione, Alessandra
,
Rosa, Fabio
Description :
BACKGROUND: Several genes encoding for DNA repair molecules implicated in maintaining genomic integrity have been proposed as cancer-susceptibility genes. Although efforts have been made to create synopses for specific fields that summarize the data from genetic association studies, such an overview...
Repository :
ECNIS Repository (Environmental Cancer Risk, Nutrition and Individual Susceptibility Repository)
Language(s) :
English
Adherence to a Mediterranean diet and risk of gastric adenocarcinoma within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study.
Author(s) :
Buckland, Genevieve
,
Agudo, Antonio
,
Luján, Leila
,
Jakszyn, Paula
,
Bueno-de-Mesquita, H. Bas
,
Palli, Domenico
,
Boeing, Heiner
Description :
BACKGROUND: The Mediterranean dietary pattern is believed to protect against cancer, although evidence from cohort studies that have examined particular cancer sites is limited. OBJECTIVE: We aimed to explore the association between adherence to a relative Mediterranean diet (rMED) and incident gast...
Repository :
ECNIS Repository (Environmental Cancer Risk, Nutrition and Individual Susceptibility Repository)
Language(s) :
English
Aging and defense against generation of 8-oxo-7,8-dihydro-2'-deoxyguanosine in DNA.
Author(s) :
Mikkelsen, Lone
,
Bialkowski, Karol
,
Risom, Lotte
,
Lohr, Mille
,
Loft, Steffen
,
Moller, Peter
Description :
The imbalance between the formation of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) in DNA and the efficiency of cellular systems of DNA protection and repair is considered an important factor in the age-dependent development of cancer. This study investigated the relationship between oxidatively d...
Repository :
ECNIS Repository (Environmental Cancer Risk, Nutrition and Individual Susceptibility Repository)
Language(s) :
English
An ECVAG trial on assessment of oxidative damage to DNA measured by the comet assay.
Author(s) :
Johansson, Clara
,
Moller, Peter
,
Forchhammer, Lykke
,
Loft, Steffen
,
Godschalk, Roger W. L.
,
Langie, Sabine A. S.
Description :
The increasing use of single cell gel electrophoresis (the comet assay) highlights its popularity as a method for detecting DNA damage, including the use of enzymes for assessment of oxidatively damaged DNA. However, comparison of DNA damage levels between laboratories can be difficult due to differ...
Repository :
ECNIS Repository (Environmental Cancer Risk, Nutrition and Individual Susceptibility Repository)
Language(s) :
English