Results
repositories = "Document Server@UHasselt"
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Joint modeling of phenotipic variables and gene expression data in early drug development experiments
Author(s) :
Perualila, Nolen Joy
Description :
Drug development benefits enormously from a microarray experiment, a tool that allows accurate and relatively inexpensive collection of gene expression information for thousands of genes at a time. Recently, it has become a commonplace in biomedical research to monitor gene expression levels associa...
Repository :
Document Server@UHasselt
Language(s) :
English
Large scale prediction of phenotipic variables using gene expression data
Author(s) :
Ndah, Elvis
Description :
Motivation: Microarray technologies are increasingly being used in early drug development. When the gene expression data from microarray experiments also contains the IC50 values of a drug, it is of interest to predict the dosage based on the gene expression profiles. In this study, the supervised p...
Repository :
Document Server@UHasselt
Language(s) :
English
Analysis of Dose-response OMICS Experiment in a Two-Way Analysis of Variance Under Ordered Constraint
Author(s) :
El Aalamat, Yousef
Description :
Repository :
Document Server@UHasselt
Language(s) :
English
Development of mutivariate analysis tools for NMR metabonomics data
Author(s) :
Dubois, Nicolas
Description :
The response of an organism to stimuli that cause diseases or injuries is utterly complex and unpredictable. By measuring and mathematically modeling changes in the levels of the products of metabolism found in biological fluids and tissues, metabonomics offers a fresh insight into the effects of di...
Repository :
Document Server@UHasselt
Language(s) :
English
Using gene expression data to predict dose-response curves
Author(s) :
Haldermans, Philippe
Description :
DNA microarrays allow us to monitor thousands of genes simultaneously. One area of interest is oncology, where we want to predict the response of a patient to a certain compound, using the microarray data. The burden of microarrays is the fact that the number of variables (p) is much larger than the...
Repository :
Document Server@UHasselt
Language(s) :
English
Investigating factors associated with HIV among 15 to 24 year old females
Author(s) :
Mzolo, Thembile
Description :
Among the sub-saharan African countries South Africa has the highest number of people who are living with HIV and AIDS in the world. HIV prevalence have remain high among young females. In this study we focus on the factors associated with HIV among females in age group 15 to 24 years where the outc...
Repository :
Document Server@UHasselt
Language(s) :
English
Classification and class prediction for different chemical structures using gene expression data
Author(s) :
Jong, Victor Lih
Description :
For years microarray-based classification has been a major topic in statistics, bioinformatics and biomedical research but because of the large number of variables as compared to the sample size, traditional statistical methods have been unsatisfactory. Thus, special methods for microarray data toge...
Repository :
Document Server@UHasselt
Language(s) :
English
Joint modeling of phenotypic variables and gene expression data for compound screening
Author(s) :
Patwary, Md. Fazlul Karim
Description :
The objective of this thesis is to identify the set of genes that can be used to screening out compounds with the help of joint modelling technique.
Repository :
Document Server@UHasselt
Language(s) :
English
Evaluation of progression free survival as surrogate endpoint for overall survival for prostate cancer treatment
Author(s) :
Bigirumurame, Theophile
Description :
In some clinical research, the endpoint of greatest relevance to inferences concerning therapeutic efficacy is frequently not practical or even feasible to measure. Sometimes the determination of the true endpoint is difficult, requiring an expensive, invasive or uncomfortable procedure.
In some tr...
Repository :
Document Server@UHasselt
Language(s) :
English
Adjusting for crossover bias in an observational study for patients with multiple myeloma
Author(s) :
Kalinjuma, Aneth Vedastus
Description :
Repository :
Document Server@UHasselt
Language(s) :
English