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repositories = "DIAL - Dépôt Institutionnel de l'Académie Louvain"
> : "Macrophages"
(x)
Changes in function of iron-loaded alveolar macrophages after in vivo administration of desferrioxamine and/or chloroquine
Description :
Both desferrioxamine (DFO) and chloroquine can significantly reduce hepatic iron in experimental animals with iron overload by chelating iron from the low-molecular-weight pool or decreasing iron uptake by the transferrin-transferrin receptor cycle, respectively. However, no previous studies have in...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Does the haemosiderin iron core determine its potential for chelation and the development of iron-induced tissue damage?
Author(s) :
Ward, Roberta J.
,
Legssyer, R
,
Henry, C
,
Crichton, RR.
,
5th International Symposium on Applied Bioinorganic Chemistry (5 ISABC)
Description :
Haemosiderin, the major iron storage protein in tissues of iron-loaded tissues shows heterogeneity with respect to both its iron mineralisation product and associated protein. Such mineralisation products have been characterised by a variety of physical techniques including Mossbauer spectroscopy, e...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Effect of retinoic acid on asbestos induced plasminogen activator activity of peritoneal macrophages.
Description :
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Relative contributions of affinity and intrinsic efficacy to aryl hydrocarbon receptor ligand potency
Author(s) :
Lison, Dominique
Description :
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Involvement of iron, nuclear factor-kappa B (NF-KB) and prostaglandins in the pathogenesis of peritoneal endometriosis-associated inflammation: A review
Author(s) :
Lousse, Jean-Christophe
,
Defrere, Sylvie
,
Gonzalez Ramos, Reinaldo
,
Van Langendonckt, Anne
,
Colette, Sébastien
Description :
Peritoneal endometriosis is a chronic pelvic inflammatory disease, characterized by increased numbers of peritoneal macrophages and their secreted products such as cytokines, growth and angiogenic factors in peritoneal fluid. Inflammation plays a major role in pain and infertility associated with en...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
Undetermined
Influence of the Theiler's virus L* protein on macrophage infection, viral persistence, and neurovirulence.
Description :
The genome of picornaviruses contains a large open reading frame (ORF) translated as a precursor polypeptide that is processed to yield all the proteins necessary for the viral life cycle. In persistent but not in neurovirulent strains of Theiler's virus, an overlapping ORF encodes an additional 18-...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Modulation of the cellular accumulation and intracellular activity of daptomycin towards phagocytized Staphylococcus aureus by the P-glycoprotein (MDR1) efflux transporter in human THP-1 macrophages and madin-darby canine kidney cells
Author(s) :
Lemaire, Sandrine
,
Van Bambeke, Françoise
,
Mingeot-Leclercq, Marie-Paule
,
Tulkens, Paul M.
Description :
P-glycoprotein (P-gp; MDR1), a major efflux transporter, recognizes various antibiotics and is present in macrophages. We have examined its effect on the modulation of the intracellular accumulation and activity of daptomycin towards phagocytized Staphylococcus aureus (ATCC 25923) in human THP-1 mac...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Intracellular rescuing of a B. melitensis 16M virB mutant by co-infection with a wild type strain.
Description :
Brucella is a broad-range, facultative intracellular pathogen that can survive and replicate in an endoplasmic reticulum (ER)-derived replication niche by preventing fusion of its membrane-bound compartment with late endosomes and lysosomes. This vacuolar hijacking was demonstrated to be dependent o...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Comparative activity of quinolones (ciprofloxacin, levofloxacin, moxifloxacin and garenoxacin) against extracellular and intracellular infection by Listeria monocytogenes and Staphylococcus aureus in J774 macrophages.
Author(s) :
Seral, C
,
Barcia-Macay, M
,
Mingeot-Leclercq, M P
,
Tulkens, Paul
,
Van Bambeke, Françoise
Description :
OBJECTIVES: Quinolones accumulate in eukaryotic cells and show activity against a large array of intracellular organisms, but systematic studies aimed at examining their pharmacodynamic profile against intracellular bacteria are scarce. The present work aims at comparing intracellular-to-extracellul...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Mixed-lipid storage disorder induced in macrophages and fibroblasts by oritavancin (LY333328), a new glycopeptide antibiotic with exceptional cellular accumulation
Author(s) :
Van Bambeke, Françoise
,
Saffran, Jennifer
,
Mingeot-Leclercq, Marie-Paule
,
Tulkens, Paul M.
Description :
Oritavancin, a semisynthetic derivative of vancomycin endowed with a cationic amphiphilic character, accumulates to large extent in the lysosomes of eukaryotic cells (F. Van Bambeke, S. Carryn, C. Seral, H. Chanteux, D. Tyteca, M. P. Mingeot-Leclercq, and P. M. Tulkens, Antimicrob. Agents Chemother....
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English