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repositories = "DIAL - Dépôt Institutionnel de l'Académie Louvain"
> : "Macrophages"
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Enhancement of autoantibody pathogenicity by viral infections in mouse models of anemia and thrombocytopenia.
Author(s) :
Musaji, Andrei
,
Meite, Mory
,
Detalle, Laurent
,
Franquin, Stéphanie
,
Cormont, Françoise
,
Préat, Véronique
,
Izui, Shozo
Description :
Viral infections are involved in the pathogenesis of blood autoimmune diseases such as hemolytic anemia and thrombocytopenia. Although antigenic mimicry has been proposed as a major mechanism by which viruses could trigger the development of such diseases, it is not easy to understand how widely dif...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Influence of efflux transporters on the accumulation and efflux of four quinolones (ciprofloxacin, levofloxacin, garenoxacin, and moxifloxacin) in J774 macrophages
Author(s) :
Michot, Jean-Michel
,
Seral, Cristina
,
Van Bambeke, Françoise
,
Mingeot-Leclercq, Marie-Paule
,
Tulkens, Paul M.
Description :
Ciprofloxacin is subject to efflux from J774 macrophages through a multidrug resistance-related protein-like transporter (J. M. Michot, F. Van Bambeke, M. P. Mingeot-Leclercq, and P. M. Tulkens, Antimicrob. Agents Chemother. 48:2673-2682, 2004). Here, we compare ciprofloxacin to levofloxacin, gareno...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Iron storage is significantly increased in peritoneal macrophages of endometriosis patients and correlates with iron overload in peritoneal fluid.
Author(s) :
Lousse, Jean-Christophe
,
Defrère, Sylvie
,
Van Langendonckt, Anne
,
Gras, Jérémie
,
González-Ramos, Reinaldo
,
Colette, Sébastien
Description :
OBJECTIVE: To further investigate peritoneal iron disruption in endometriosis by studying iron storage in peritoneal macrophages of patients with endometriosis compared with controls. DESIGN: Cross-sectional study. SETTING: Academic gynecology research unit in a university hospital. PATIENT(S): Fift...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
LcrG is required for efficient translocation of Yersinia Yop effector proteins into eukaryotic cells.
Description :
Extracellular Yersinia disables the immune system of its host by injecting effector Yop proteins into host cells. We show that a Yersinia enterocolitica nonpolar lcrG mutant is severely impaired in the translocation of YopE, YopH, YopM, YpkA/YopO, and YopP into eukaryotic cells. LcrG is thus require...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Non-AUG-initiated internal translation of the L* protein of Theiler's virus and importance of this protein for viral persistence.
Description :
Theiler's virus is a neurotropic murine picornavirus which, depending on the strain, causes either acute encephalitis or persistent demyelinating disease. Persistent strains of Theiler's virus (such as DA) produce an 18-kDa protein called L* from an open reading frame overlapping that encoding the v...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Interleukin 1beta mediates the effect of high D-glucose on the secretion of TNF-alpha by mouse uterine epithelial cells.
Author(s) :
Pampfer, S.
,
Cordi, Sabine
,
Dutrieux, C
,
Vanderheyden, Ivo
,
Marchand, Chantal
,
De Hertogh, René
Description :
Previous observations have shown that tumour necrosis factor alpha (TNF-alpha) synthesis is increased in the uterus of diabetic rats and that the epithelial layer lining the uterine lumen is the major site of TNF-alpha over-production. In the present study, TNF-alpha secretion was found to be stimul...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Infection of macrophages by Theiler's murine encephalomyelitis virus is highly dependent on their activation or differentiation state.
Description :
Macrophages are the main targets of Theiler's murine encephalomyelitis virus (TMEV) during persistent demyelinating infection of mice. Replication of TMEV in macrophages was previously shown to depend on their activation state. Here, we show that the quality of the serum used for culture drastically...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Effects of marginal iron overload on iron homeostasis and immune function in alveolar macrophages isolated from pregnant and normal rats.
Author(s) :
Ward, Roberta J.
,
Wilmet, Stephanie
,
Legssyer, Rachida
,
Leroy, Daniel
,
Toussaint, Louise
,
Crichton, Robert
,
Pierreux, Christophe
Description :
The effects of changes in macrophage iron status, induced by single or multiple iron injections, iron depletion or pregnancy, on both immune function and mRNA expression of genes involved in iron influx and egress have been evaluated. Macrophages isolated from iron deficient rats, or pregnant rats a...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
The inhibitory potencies of monoclonal antibodies to the macrophage adhesion molecule sialoadhesin are greatly increased following PEGylation.
Description :
PEGylation of antibodies is known to increase their half-life in systemic circulation, but nothing is known regarding whether PEGylation can improve the inhibitory potency of antibodies against target receptors. In this paper, we have examined this question using antibodies directed to Sialoadhesin ...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Increased activation of nuclear factor-kappa B (NF-kappaB) in isolated peritoneal macrophages of patients with endometriosis.
Author(s) :
Lousse, Jean-Christophe
,
Van Langendonckt, Anne
,
González-Ramos, Reinaldo
,
Defrère, Sylvie
,
Renkin, Emmanuelle
Description :
Endometriosis is characterized by pelvic inflammation that shows an increased number of activated peritoneal macrophages and their secreted products such as cytokines, growth factors, and angiogenic factors. Our results show that activation of nuclear factor-kappa B (NF-kappaB), a pro-inflammatory t...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English