Results
author = "van IJcken, Wilfred"
Stable RNA markers for identification of blood and saliva stains revealed from whole genome expression analysis of time-wise degraded samples
Author(s) :
Zubakov, Dmitry
,
Hanekamp, Eline
,
Kokshoorn, Mieke
,
van IJcken, Wilfred
,
Kayser, Manfred
Description :
Human body fluids such as blood and saliva represent the most common source of biological material found at a crime scene. Reliable tissue identification in forensic science can reveal significant insights into crime scene reconstruction and can thus contribute toward solving crimes. Limitations of ...
Repository :
Europe PubMed Central
Language(s) :
English
Functional Differentiation of SWI/SNF Remodelers in Transcription and Cell Cycle Control▿ †
Description :
Drosophila BAP and PBAP represent two evolutionarily conserved subclasses of SWI/SNF chromatin remodelers. The two complexes share the same core subunits, including the BRM ATPase, but differ in a few signature subunits: OSA defines BAP, whereas Polybromo (PB) and BAP170 specify PBAP. Here, we prese...
Repository :
Europe PubMed Central
Language(s) :
English
Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells
Author(s) :
Martianov Igor
,
Choukrallah Mohamed-Amin
,
Krebs Arnaud
,
Ye Tao
,
Legras Stephanie
,
Rijkers Erikjan
,
Van Ijcken Wilfred
Description :
Abstract
Background
CREB and CREM are closely related factors that regulate transcription in response to various stress, metabolic and developmental signals. The CREMτ activator isoform is selectively expressed in haploid spermatids and plays an essential role in murine spermiogenes...
Repository :
DOAJ-Articles
Language(s) :
English
Transcription and Chromatin Organization of a Housekeeping Gene Cluster Containing an Integrated β-Globin Locus Control Region
Author(s) :
Noordermeer, Daan
,
Branco, Miguel R.
,
Splinter, Erik
,
Klous, Petra
,
van IJcken, Wilfred
,
Swagemakers, Sigrid
,
Koutsourakis, Manousos
Description :
The activity of locus control regions (LCR) has been correlated with chromatin decondensation, spreading of active chromatin marks, locus repositioning away from its chromosome territory (CT), increased association with transcription factories, and long-range interactions via chromatin looping. To i...
Repository :
Europe PubMed Central
Language(s) :
English
Correction: Transcription and Chromatin Organization of a Housekeeping Gene Cluster Containing an Integrated β-Globin Locus Control Region
Author(s) :
Noordermeer, Daan
,
Branco, Miguel R.
,
Splinter, Erik
,
Klous, Petra
,
van IJcken, Wilfred
,
Swagemakers, Sigrid
,
Koutsourakis, Manousos
Description :
Repository :
Europe PubMed Central
Language(s) :
English
The ubiquitin-conjugating enzyme HR6B is required for maintenance of X chromosome silencing in mouse spermatocytes and spermatids
Author(s) :
Mulugeta Achame, Eskeatnaf
,
Wassenaar, Evelyne
,
Hoogerbrugge, Jos W
,
Sleddens-Linkels, Esther
,
Ooms, Marja
,
Sun, Zu-Wen
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells
Author(s) :
Martianov, Igor
,
Choukrallah, Mohamed-Amin
,
Krebs, Arnaud
,
Ye, Tao
,
Legras, Stephanie
,
Rijkers, Erikjan
,
Van Ijcken, Wilfred
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Modulation of Androgen Receptor Signaling in Hormonal Therapy-Resistant Prostate Cancer Cell Lines
Author(s) :
Marques, Rute B.
,
Dits, Natasja F.
,
Erkens-Schulze, Sigrun
,
van IJcken, Wilfred F. J.
,
van Weerden, Wytske M.
Description :
Repository :
Europe PubMed Central
Language(s) :
English
MN1 affects expression of genes involved in hematopoiesis and can enhance as well as inhibit RAR/RXR-induced gene expression
Author(s) :
Meester-Smoor, Magda A.
,
Janssen, Marjolein J.F.W.
,
Grosveld, Gerard C.
,
de Klein, Annelies
,
van IJcken, Wilfred F.J.
Description :
The oncoprotein meningioma 1 (MN1) is overexpressed in several subtypes of acute myeloid leukemia (AML) and overexpression was associated with a poor response to chemotherapy. MN1 is a cofactor of retinoic acid receptor/retinoic x receptor (RAR/RXR)-mediated transcription and this study identified g...
Repository :
Europe PubMed Central
Language(s) :
English
Left ventricular remodeling in swine after myocardial infarction: a transcriptional genomics approach
Author(s) :
Kuster, Diederik W. D.
,
Merkus, Daphne
,
Kremer, Andreas
,
van IJcken, Wilfred F. J.
,
de Beer, Vincent J.
,
Verhoeven, Adrie J. M.
Description :
Despite the apparent appropriateness of left ventricular (LV) remodeling following myocardial infarction (MI), it poses an independent risk factor for development of heart failure. There is a paucity of studies into the molecular mechanisms of LV remodeling in large animal species. We took an unbias...
Repository :
Europe PubMed Central
Language(s) :
English