Results
author = "Willemsen, R."
Gaucher Disease: an Immunoelectron Microscopic and Biochemical Study
Author(s) :
Willemsen, R.
Description :
Repository :
RePub (Erasmus University Repository)
Language(s) :
English
Small at Birth: cardiovascular and metabolic health of subjects born SGA and/or preterm and effects of growth hormone treatment
Author(s) :
Willemsen, R.H.
Description :
This doctoral thesis describes cardiovascular and metabolic risk factors in children
and young adults with a small size at birth, either due to preterm or SGA birth. For
those born SGA with persistent short stature, the effects of GH treatment on these risk
factors were studied. This first chapter d...
Repository :
RePub (Erasmus University Repository)
Language(s) :
English
CD8α Coreceptor to Improve TCR Gene Transfer to Treat Melanome: Down-Regulation of Tumor-Specific Production of IL-4, IL-5 and IL-10
Author(s) :
Willemsen, R.A.
Description :
Therapeutic success of TCR gene transfer to treat tumors depends on the ability of redirected T cells to become activated upon tumor recognition in vivo. Help provided by tumor-specific Th1 cells is reported to relieve T cells from an anergized state and to induce tumor regression. We recently demon...
Repository :
RePub (Erasmus University Repository)
Language(s) :
English
Een aantal aspecten in theorie en praktijk van het investeringsgedrag van ondernemingen
Author(s) :
Willemsen, R.J.H.
Description :
Repository :
Theses database, Tilburg University
Language(s) :
Dutch
Twin sisters, monozygotic with the fragile X mutation, but with a different phenotype
Description :
The absence of the fragile X mental retardation protein (FMRP) results in
fragile X syndrome. All males with a full mutation in the FMR1 gene and an
inactive FMR1 gene are mentally retarded while 60% of the females with a
full mutation are affected. Here we describe mon...
Repository :
RePub (Erasmus University Repository)
Language(s) :
English
Twin sisters, monozygotic with the fragile X mutation, but with a different phenotype
Description :
The absence of the fragile X mental retardation protein (FMRP) results in fragile X syndrome. All males with a full mutation in the FMR1 gene and an inactive FMR1 gene are mentally retarded while 60% of the females with a full mutation are affected. Here we describe monozygotic twin sisters who both...
Repository :
Europe PubMed Central
Language(s) :
English
Ubiquitin-positive intranuclear inclusions in neuronal and glial cells in a mouse model of the fragile X premutation
Description :
Fragile X-associated tremor/ataxia syndrome (FXTAS) is an adult-onset neurodegenerative disorder caused by CGG trinucleotide repeat expansions in the fragile X mental retardation 1 (FMR1) gene. The neuropathological hallmark of the disease is the presence of ubiquitin-positive intranuclear inclusion...
Repository :
RePub (Erasmus University Repository)
Language(s) :
English
Hepatic lipase is localized at the parenchymal cell microvilli in rat liver
Description :
Hepatic lipase (HL) is thought to be located at the vascular endothelium
in the liver. However, it has also been implicated in the binding and
internalization of chylomicron remnants in the parenchymal cells. In view
of this apparent discrepancy between localization and...
Repository :
RePub (Erasmus University Repository)
Language(s) :
English
Longitudinal changes in insulin sensitivity and body composition of small-for-gestational-age adolescents after cessation of growth hormone treatment
Description :
Context: GH treatment reduces insulin sensitivity (Si). For small-for-gestational-age (SGA) subjects, who might have an increased risk to develop cardiovascular disease and type 2 diabetes, it is still uncertain how Si, β-cell function, and body composition change over time after stopping GH treatme...
Repository :
RePub (Erasmus University Repository)
Language(s) :
English
Transport of fragile X mental retardation protein via granules in neurites of PC12 cells
Author(s) :
Diego Otero, Y. de
,
Severijnen, L.A.
,
Cappellen, W.A. van
,
Schrier, M.
,
Willemsen, R.
,
Oostra, B.A.
Description :
Lack of fragile X mental retardation protein (FMRP) causes fragile X
syndrome, a common form of inherited mental retardation. FMRP is an RNA
binding protein thought to be involved in translation efficiency and/or
trafficking of certain mRNAs. Recently, a subset of mRNAs to which FM...
Repository :
RePub (Erasmus University Repository)
Language(s) :
English