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author = "Weeks, Robert J."
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Found 4 documents, displaying page 1 of 1

Technical Considerations for Reduced Representation Bisulfite Sequencing with Multiplexed Libraries

Author(s) : Chatterjee, Aniruddha , Rodger, Euan J. , Stockwell, Peter A. , Weeks, Robert J. , Morison, Ian M.
Description : Reduced representation bisulfite sequencing (RRBS), which couples bisulfite conversion and next generation sequencing, is an innovative method that specifically enriches genomic regions with a high density of potential methylation sites and enables investigation of DNA methylation at single-nucleoti...
Repository : Europe PubMed Central
Language(s) : English

Silencing of TESTIN by dense biallelic promoter methylation is the most common molecular event in childhood acute lymphoblastic leukaemia

Author(s) : Weeks, Robert J , Kees, Ursula R , Song, Sarah , Morison, Ian M
Description :
Repository : Europe PubMed Central
Language(s) : English

Silencing of TESTIN by dense biallelic promoter methylation is the most common molecular event in childhood acute lymphoblastic leukaemia

Author(s) : Weeks Robert J , Kees Ursula R , Song Sarah , Morison Ian M
Description :

Abstract

Background

Aberrant promoter DNA methylation has been reported in childhood acute lymphoblastic leukaemia (ALL) and has the potential to contribute to its onset and outcome. However, few reports demonstrate consistent, prevalent and dense promoter methylation, associated wi...

Repository : DOAJ-Articles
Language(s) : English

Alkylpurine–DNA–N-Glycosylase Knockout Mice Show Increased Susceptibility to Induction of Mutations by Methyl Methanesulfonate

Author(s) : Elder, Rhoderick H. , Jansen, Jacob G. , Weeks, Robert J. , Willington, Mark A. , Deans, Bryan , Watson, Amanda J. , Mynett, Kurt J.
Description : Alkylpurine-DNA-N-glycosylase (APNG) null mice have been generated by homologous recombination in embryonic stem cells. The null status of the animals was confirmed at the mRNA level by reverse transcription-PCR and by the inability of cell extracts of tissues from the knockout (ko) animals to relea...
Repository : Europe PubMed Central
Language(s) : English
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Found 4 documents, displaying page 1 of 1