Results
author = "Watanabe, Takashi"
Crystal structure of enoyl–acyl carrier protein reductase (FabK) from Streptococcus pneumoniae reveals the binding mode of an inhibitor
Author(s) :
Saito, Jun
,
Yamada, Mototsugu
,
Watanabe, Takashi
,
Iida, Maiko
,
Kitagawa, Hideo
,
Takahata, Sho
,
Ozawa, Tomohiro
,
Takeuchi, Yasuo
Description :
Enoyl–acyl carrier protein (ACP) reductases are critical for bacterial type II fatty acid biosynthesis and thus are attractive targets for developing novel antibiotics. We determined the crystal structure of enoyl–ACP reductase (FabK) from Streptococcus pneumoniae at 1.7 Å resolution. There was one ...
Repository :
Europe PubMed Central
Language(s) :
English
Assessment of Japanese Stimulant Control Law Offenders Using the Addiction Severity Index—Japanese Version: Comparison with Patients in Treatment Settings
Author(s) :
Watanabe, Takashi
,
Ogai, Yasukazu
,
Koga, Takehiro
,
Senoo, Eiichi
,
Nakamura, Kazuhiko
,
Mori, Norio
,
Ikeda, Kazutaka
Description :
The present study assessed problems in Japanese prisoners (inmates) who abused methamphetamine. Fifty-two male inmates were assessed in 2005–2007 using the Addiction Severity Index-Japanese version and compared with 55 male methamphetamine abusers in hospitals and recovery centers. The χ2 and Mann-W...
Repository :
Europe PubMed Central
Language(s) :
English
Comparison of lung cancer cell lines representing four histopathological subtypes with gene expression profiling using quantitative real-time PCR
Author(s) :
Watanabe, Takashi
,
Miura, Tomohiro
,
Degawa, Yusuke
,
Fujita, Yuna
,
Inoue, Masaaki
,
Kawaguchi, Makoto
,
Furihata, Chie
Description :
Repository :
Europe PubMed Central
Language(s) :
English
EB1 promotes microtubule dynamics by recruiting Sentin in Drosophila cells
Author(s) :
Li, Wenjing
,
Miki, Tomohiro
,
Watanabe, Takashi
,
Kakeno, Mai
,
Sugiyama, Ikuko
,
Kaibuchi, Kozo
,
Goshima, Gohta
Description :
The microtubule plus end regulator EB1 brings Sentin and possibly a microtubule polymerase to microtubule plus ends to promote microtubule dynamics.
Repository :
Europe PubMed Central
Language(s) :
English
A calmodulin inhibitor, W-7 influences the effect of cyclic adenosine 3', 5'-monophosphate signaling on ligninolytic enzyme gene expression in Phanerochaete chrysosporium
Author(s) :
Sakamoto, Takaiku
,
Yao, Yuki
,
Hida, Yoshifumi
,
Honda, Yoichi
,
Watanabe, Takashi
,
Hashigaya, Wataru
,
Suzuki, Kazumi
Description :
The capacity of white-rot fungi to degrade wood lignin may be highly applicable to the development of novel bioreactor systems, but the mechanisms underlying this function are not yet fully understood. Lignin peroxidase (LiP) and manganese peroxidase (MnP), which are thought to be very important for...
Repository :
Europe PubMed Central
Language(s) :
English
Endoscopically observable white nodule caused by distal intramural lymphatic spread of rectal cancer: a case report
Author(s) :
Tsumura, Ayako
,
Yokoyama, Shozo
,
Takifuji, Katsunari
,
Hotta, Tsukasa
,
Matsuda, Kenji
,
Watanabe, Takashi
,
Mitani, Yasuyuki
Description :
This report describes a case of rectal cancer with endoscopically observable white nodules caused by distal intramural lymphatic spread. A 57-year-old female presented to our hospital with frequent diarrhea and hemorrhoids. Computed tomography showed bilateral ovarian masses and three hepatic tumors...
Repository :
Europe PubMed Central
Language(s) :
English
Aberrant promoter methylation and expression of the imprinted PEG3 gene in glioma
Author(s) :
Otsuka, Susumu
,
Maegawa, Shinji
,
Takamura, Ayumi
,
Kamitani, Hideki
,
Watanabe, Takashi
,
Oshimura, Mitsuo
,
Nanba, Eiji
Description :
Glioma includes astrocytoma, oligodendroglioma, ependymoma and glioblastoma. We previously reported the epigenetic silencing of paternally expressed gene 3 (PEG3) in glioma cell lines. In this study, we investigated methylation of an exonic CpG island in the promoter region and the expression of PEG...
Repository :
Europe PubMed Central
Language(s) :
English
Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine
Author(s) :
Czéh, Boldizsár
,
Michaelis, Thomas
,
Watanabe, Takashi
,
Frahm, Jens
,
de Biurrun, Gabriel
,
van Kampen, Marja
,
Bartolomucci, Alessandro
Description :
Stress-induced structural remodeling in the adult hippocampus, involving debranching and shortening of dendrites and suppression of neurogenesis, provides a cellular basis for understanding the impairment of neural plasticity in the human hippocampus in depressive illness. Accordingly, reversal of s...
Repository :
Europe PubMed Central
Language(s) :
English
Positive Role of IQGAP1, an Effector of Rac1, in Actin-Meshwork Formation at Sites of Cell-Cell ContactD⃞V⃞
Author(s) :
Noritake, Jun
,
Fukata, Masaki
,
Sato, Kazumasa
,
Nakagawa, Masato
,
Watanabe, Takashi
,
Izumi, Nanae
,
Wang, Shujie
,
Fukata, Yuko
Description :
The small guanosine triphosphatase Rac1 is activated by E-cadherin-mediated cell-cell adhesion and is required for the accumulation of actin filaments, E-cadherin, and β-catenin at sites of cell-cell contact. However, the modes of activation and action of Rac1 remain to be clarified. We here found t...
Repository :
Europe PubMed Central
Language(s) :
English
Effect of Lignocellulose-Derived Inhibitors on Growth of and Ethanol Production by Growth-Arrested Corynebacterium glutamicum R▿
Author(s) :
Sakai, Shinsuke
,
Tsuchida, Yoshiki
,
Okino, Shohei
,
Ichihashi, Osamu
,
Kawaguchi, Hideo
,
Watanabe, Takashi
,
Inui, Masayuki
Description :
In cellulosic ethanol production, pretreatment of a biomass to facilitate enzymatic hydrolysis inevitably yields fermentation inhibitors such as organic acids, furans, and phenols. With representative inhibitors included in the medium at various concentrations, individually or in various combination...
Repository :
Europe PubMed Central
Language(s) :
English