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author = "Turro, Nicholas J."

Found 25 documents, displaying page 1 of 3

Supramolecular structure and dynamics

Author(s) : Turro, Nicholas J.
Description :
Repository : Europe PubMed Central
Language(s) : English

Supramolecular organic photochemistry: Control of covalent bond formation through noncovalent supramolecular interactions and magnetic effects

Author(s) : Turro, Nicholas J.
Description : Supramolecular organic photochemistry, a field concerned with the interaction of light with supramolecular assemblies of organic molecules, has been inspired by the remarkable structural and dynamic features of guest@host chemistry, particularly as exemplified by enzymes. Exemplars of supramolecular...
Repository : Europe PubMed Central
Language(s) : English

Influence of nuclear spin on chemical reactions: Magnetic isotope and magnetic field effects (A Review)

Author(s) : Turro, Nicholas J.
Description : The course of chemical reactions involving radical pairs may depend on occurrence and orientation of nuclear spins in the pairs. The influence of nuclear spins is maximized when the radical pairs are confined to a space that serves as a cage that allows a certain degree of independent diffusional an...
Repository : Europe PubMed Central
Language(s) : English

Molecular beacons with intrinsically fluorescent nucleotides

Description : We report the design, synthesis and characterization of a novel molecular beacon (MB-FB) which uses the fluorescent bases (FB) 2-aminopurine (AP) and pyrrolo-dC (P-dC) as fluorophores. Because the quantum yield of these FB depend on hybridization with complementary target, the fluorescent properties...
Repository : Europe PubMed Central
Language(s) : English

Photocleavage of a 2-nitrobenzyl linker bridging a fluorophore to the 5′ end of DNA

Description : Three single-stranded DNA molecules of different lengths were synthesized and characterized, each containing a fluorescent dye (6-carboxyfluorescein) connected to the 5′ end via a photocleavable 2-nitrobenzyl linker and a biotin moiety at the 3′ end. UV irradiation (λ ≈ 340 nm) of solutions containi...
Repository : Europe PubMed Central
Language(s) : English

A photocleavable fluorescent nucleotide for DNA sequencing and analysis

Description : DNA sequencing by synthesis during a polymerase reaction using laser-induced fluorescence detection is an approach that has a great potential to increase the throughput and data quality of DNA sequencing. We report the design and synthesis of a photocleavable fluorescent nucleoside triphosphate, one...
Repository : Europe PubMed Central
Language(s) : English

Light-switching excimer probes for rapid protein monitoring in complex biological fluids

Description : Quantitative protein bioanalysis in complex biological fluids presents considerable challenges in biological studies and disease diagnosis. The major obstacles are the background signals from both the probe and the biological fluids where the proteins reside. We have molecularly engineered light-swi...
Repository : Europe PubMed Central
Language(s) : English

Design and synthesis of a photocleavable biotinylated nucleotide for DNA analysis by mass spectrometry

Description : We report here the design, synthesis and evaluation of a novel photocleavable (PC) biotinylated nucleotide analog, dUTP-PC-Biotin, for DNA polymerase extension reaction to isolate DNA products for mass spectrometry (MS) analysis. This nucleotide analog has a biotin moiety attached to the 5-position ...
Repository : Europe PubMed Central
Language(s) : English

Photocleavable fluorescent nucleotides for DNA sequencing on a chip constructed by site-specific coupling chemistry

Description : DNA sequencing by synthesis on a solid surface offers new paradigms to overcome limitations of electrophoresis-based sequencing methods. Here we report DNA sequencing by synthesis using photocleavable (PC) fluorescent nucleotides [dUTP-PC-4,4-difluoro-4-bora-3α,4α-diaza-s-indacene (Bodipy)-FL-510, d...
Repository : Europe PubMed Central
Language(s) : English

Found 25 documents, displaying page 1 of 3