Results
author = "Tabernero, J."
Different hCG assays to measure ectopic hCG secretion in bladder carcinoma patients.
Description :
We evaluated the clinical performance of assays measuring intact human chorionic gonadotropin alone (i-hCG), intact and nicked human chorionic gonadotropin (i-hCG and hCGn), free beta-subunit (free beta-hCG) and total beta-human chorionic gonadotropin (t-hCG) using different commercial kits, in a gr...
Repository :
Europe PubMed Central
Language(s) :
English
Pharmacokinetics of phosphomycin during haemofiltration.
Author(s) :
Fernandez Lastra, C
,
Mariño, E L
,
Dominguez-Gil, A
,
Tabernero, J M
,
Grande Villoria, J
Description :
The pharmacokinetics of phosphomycin were studied in 10 adult patients with terminal renal impairment during a 4 h haemofiltration session. A single i.v. dose of 30 mg/kg of the antibiotic was administered to each patient at the beginning of the haemofiltration session. The half-life of the slow dis...
Repository :
Europe PubMed Central
Language(s) :
English
Microsatellite instability due to hMLH1 deficiency is associated with increased cytotoxicity to irinotecan in human colorectal cancer cell lines
Author(s) :
Vilar, E
,
Scaltriti, M
,
Balmaña, J
,
Saura, C
,
Guzman, M
,
Arribas, J
,
Baselga, J
,
Tabernero, J
Description :
Around 15% of colorectal cancers (CRCs) show microsatellite instability (MSI) due to dysfunction of the mismatch repair system (MMR). As a consequence of this, MSI tumours tend to accumulate errors in mononucleotide repeats as those in genes implicated in repairing double-strand breaks (DSBs). Previ...
Repository :
Europe PubMed Central
Language(s) :
English
Randomized Phase 3 Study of Panitumumab With FOLFOX4 Compared to FOLFOX4 Alone as 1st-line Treatment (tx) for Metastatic Colorectal Cancer (mCRC): The PRIME Trial
Author(s) :
Douillard, J.Y.
,
Siena, S.
,
Cassidy, J.
,
Tabernero, J.
,
Burkes, R.
,
Barugel, M.E.
,
Humblet, Y.
,
Cunningham, D.
,
Wolf, M.
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Improved overall survival with oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment in stage II or III colon cancer in the MOSAIC trial.
Author(s) :
André, T
,
Boni, C
,
Navarro, M
,
Tabernero, J
,
Hickish, T
,
Topham, C
,
Bonetti, A
,
Clingan, P
,
Bridgewater, J
,
Rivera, F
,
de Gramont, A
Description :
PURPOSE Three-year disease-free survival (DFS) was significantly improved in patients who had undergone resection with curative intent for stage II or III colon cancer who received bolus plus continuous-infusion fluorouracil plus leucovorin (LV5FU2) with the addition of oxaliplatin (FOLFOX4). Final ...
Repository :
UCL Eprints
Language(s) :
English
Current issues in adjuvant treatment of stage II colon cancer
Author(s) :
André, T
,
Sargent, D
,
Tabernero, J
,
O'Connell, M
,
BUYSE, Marc
,
Sobrero, A
,
Misset, J.L.
,
Boni, C
,
de Gramont, A
Description :
Adjuvant chemotherapy with 5-fluorouracil modulated by folinic acid, combined with oxaliplatin, has now become an accepted standard of care for patients with stage III colon cancer. In contrast, the use of adjuvant therapy for stage II patients remains controversial, and the identification of reliab...
Repository :
Document Server@UHasselt
Language(s) :
English
Treatment of cancer with oral drugs: a position statement by the Spanish Society of Medical Oncology (SEOM)
Author(s) :
Colomer, R.
,
Alba, E.
,
González-Martin, A.
,
Paz-Ares, L.
,
Martín, M.
,
Llombart, A.
,
Rodríguez Lescure, Á.
,
Salvador, J.
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Clinical activity of patupilone in patients with pretreated advanced/metastatic colon cancer: results of a phase I dose escalation trial.
Author(s) :
Melichar, B
,
Casado, E
,
Bridgewater, J
,
Bennouna, J
,
Campone, M
,
Vitek, P
,
Delord, JP
,
Cerman, J
,
Salazar, R
,
Dvorak, J
Description :
New agents that are active in patients with metastatic colorectal cancer are needed. Patupilone (EPO906; epothilone B) is a novel microtubule-stabilising agent.
Repository :
UCL Eprints
Language(s) :
English
Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer.
Author(s) :
André, T
,
Boni, C
,
Mounedji-Boudiaf, L
,
Navarro, M
,
Tabernero, J
,
Hickish, T
,
Topham, C
,
Zaninelli, M
,
Clingan, P
,
Bridgewater, J
Description :
The standard adjuvant treatment of colon cancer is fluorouracil plus leucovorin (FL). Oxaliplatin improves the efficacy of this combination in patients with metastatic colorectal cancer. We evaluated the efficacy of treatment with FL plus oxaliplatin in the postoperative adjuvant setting.
Repository :
UCL Eprints
Language(s) :
English
Clinical activity of patupilone in patients with pretreated advanced/metastatic colon cancer: results of a phase I dose escalation trial
Author(s) :
Melichar, B
,
Casado, E
,
Bridgewater, J
,
Bennouna, J
,
Campone, M
,
Vitek, P
,
Delord, J-P
,
Cerman, J
,
Salazar, R
,
Dvorak, J
Description :
Repository :
Europe PubMed Central
Language(s) :
English