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author = "Stockman, Bronislava M."
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Found 3 documents, displaying page 1 of 1

Differential Expression of Interferon (IFN) Regulatory Factors and IFN-Stimulated Genes at Early Times after West Nile Virus Infection of Mouse Embryo Fibroblasts▿

Author(s) : Scherbik, Svetlana V. , Stockman, Bronislava M. , Brinton, Margo A.
Description : Although lineage I West Nile virus (WNV) strain Eg101 induced beta interferon (IFN-β) production as early as 12 h after infection in primary mouse embryo fibroblasts and did not inhibit the JAK-STAT signaling pathway, it was still able to replicate efficiently. To gain insights about possible viral ...
Repository : Europe PubMed Central
Language(s) : English

Positional cloning of the murine flavivirus resistance gene

Author(s) : Perelygin, Andrey A. , Scherbik, Svetlana V. , Zhulin, Igor B. , Stockman, Bronislava M. , Li, Yan , Brinton, Margo A.
Description : Inbred mouse strains exhibit significant differences in their susceptibility to viruses in the genus Flavivirus, which includes human pathogens such as yellow fever, Dengue, and West Nile virus. A single gene, designated Flv, confers this differential susceptibility and was mapped previously to a re...
Repository : Europe PubMed Central
Language(s) : English

RNase L Plays a Role in the Antiviral Response to West Nile Virus

Author(s) : Scherbik, Svetlana V. , Paranjape, Jayashree M. , Stockman, Bronislava M. , Silverman, Robert H. , Brinton, Margo A.
Description : Alleles at the Flv locus determine disease outcome after a flavivirus infection in mice. Although comparable numbers of congenic resistant and susceptible mouse embryo fibroblasts (MEFs) are infected by the flavivirus West Nile virus (WNV), resistant MEFs produce ∼100- to 150-fold lower titers than ...
Repository : Europe PubMed Central
Language(s) : English
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Found 3 documents, displaying page 1 of 1