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author = "Sniekers, Y.H."
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Found 4 documents, displaying page 1 of 1

Estrogen effects on cartilage and bone changes in models for osteoarthritis

Author(s) : Sniekers, Y.H.
Description : Osteoarthritis (OA) is a frequently occurring musculoskeletal disorder, leading to joint pain and disability. Although all tissues in the joint can be affected, the focus of this thesis is on changes in bone and cartilage. Evidence from literature suggests that estrogen may have an OA-protective eff...
Repository : RePub (Erasmus University Repository)
Language(s) : English

Determining Diffusion Coefficients in Inhomogeneous Tissues Using Fluorescence Recovery after Photobleaching

Description : Diffusion plays an important role in the transport of nutrients and signaling molecules in cartilaginous tissues. Diffusion coefficients can be measured by fluorescence recovery after photobleaching (FRAP). Available methods to analyze FRAP data, however, assume homogeneity in the environment of the...
Repository : Europe PubMed Central
Language(s) : English

Oestrogen is important for maintenance of cartilage and subchondral bone in a murine model of knee osteoarthritis

Description : Introduction: Oestrogen depletion may influence onset and/or progression of osteoarthritis. We investigated in an ovariectomized mouse model the impact of oestrogen loss and oestrogen supplementation on articular cartilage and subchondral bone in tibia and patella, and assessed bone changes in osteo...
Repository : RePub (Erasmus University Repository)
Language(s) : English

A role for subchondral bone changes in the process of osteoarthritis; a micro-CT study of two canine models

Description : BACKGROUND: This study evaluates changes in peri-articular bone in two canine models for osteoarthritis: the groove model and the anterior cruciate ligament transection (ACLT) model. METHODS: Evaluation was performed at 10 and 20 weeks post-surgery and in addition a 3-weeks time point was studied fo...
Repository : RePub (Erasmus University Repository)
Language(s) : English
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Found 4 documents, displaying page 1 of 1