Results
author = "Silvestrini, R."
Whither smooth muscle antibodies in the third millennium?
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Effect of melphalan and hyperthermia on p34cdc2 kinase activity in human melanoma cells.
Description :
We previously reported that combined treatment with melphalan and mild hyperthermia (1 h at 42 degrees C) caused a synergistic cytotoxic effect in JR8 melanoma cells, paralleled by a stabilisation of a melphalan-induced G2-phase cell block. In this study, we investigated the effect of melphalan and ...
Repository :
Europe PubMed Central
Language(s) :
English
Lack of a correlation between micronucleus formation and radiosensitivity in established and primary cultures of human tumours.
Description :
The radiation-induced genotoxic damage in three established cell lines and 15 primary cultures of human malignant melanoma and ovarian carcinoma showing different radiosensitivity was tested by the cytokinesis-block micronucleus assay. A dose-related increase in micronucleus frequency was observed i...
Repository :
Europe PubMed Central
Language(s) :
English
INHIBITING EFFECT OF THE NEW CYTOTOXIC ANTIBIOTIC DAUNOMYCIN ON NUCLEIC ACIDS AND MITOTIC ACTIVITY OF HELA CELLS
Description :
The effect has been studied of Actinomycin D, Daunomycin (Da.), and Da. N acetyl derivative on mitotic activity and on the nucleic acid synthesis of in vitro HeLa cell cultures. The experiments were carried out by means of the radioautographic technique using stripping films. The relative uptake of...
Repository :
Europe PubMed Central
Language(s) :
English
Induction of apoptosis by taxol and cisplatin and effect on cell cycle-related proteins in cisplatin-sensitive and -resistant human ovarian cells.
Description :
The effect of taxol (TX) and cisplatin (CDDP), singly or in association, was assessed on two human ovarian cancer cell lines, one sensitive (A2780) and one resistant (A2780 cp8) to CDDP. Cell lines showed a similar sensitivity to TX, whereas different cytotoxicity results were obtained in the two ce...
Repository :
Europe PubMed Central
Language(s) :
English
Expression of high-affinity 67-kDa laminin receptors in primary breast cancers and metachronous metastatic lesions or contralateral cancers.
Description :
The presence of high-affinity 67-kDa laminin receptors, detected immunohistochemically, was determined on 63 primary breast cancers and on metachronous metastatic lesions or contralateral cancers from the same patients. A disagreement was observed in two-thirds of the cases. In particular, laminin r...
Repository :
Europe PubMed Central
Language(s) :
English
Contribution of 3H-thymidine labelling index and flow cytometric S-phase in predicting survival of patients with non-Hodgkin's lymphoma.
Author(s) :
Costa, A.
,
Silvestrini, R.
,
Giardini, R.
,
Messina-Gabrielli, G.
,
Boracchi, P.
,
Veneroni, S.
Description :
The 3H-thymidine labelling index (3H-dT LI) of cell suspensions from fresh material and the flow cytometric S-phase (FCM-S) of nuclei recovered from paraffin blocks were determined on the same pathologic lymph node specimen for 190 non-Hodgkin's lymphomas (NHLs). FCM-S was defined by a planimetric m...
Repository :
Europe PubMed Central
Language(s) :
English
Cell kinetics: an independent prognostic variable in stage II melanoma of the skin.
Author(s) :
Costa, A.
,
Silvestrini, R.
,
Mezzanotte, G.
,
Vaglini, M.
,
Grignolio, E.
,
Clemente, C.
,
Cascinelli, N.
Description :
The prognostic role of cell kinetics (expressed as 3H-thymidine labelling index, 3H-TdR LI) was assessed on 145 patients with pathologic stage II melanoma subjected only to therapeutic lymph node dissection. The 3H-TdR LI determined on metastatic nodes was related to relapse-free survival and to sur...
Repository :
Europe PubMed Central
Language(s) :
English
P53 expression, DNA ploidy and S-phase cell fraction in operable locally advanced non-small-cell lung cancer.
Author(s) :
Costa, A.
,
Silvestrini, R.
,
Mochen, C.
,
Lequaglie, C.
,
Boracchi, P.
,
Faranda, A.
,
Vessecchia, G.
,
Ravasi, G.
Description :
The identification of biomarkers to complement pathological stage for a more accurate prognosis and help clinicians decide on treatment is still an open problem for patients with lung cancer. Expression of P53 protein was detected by an immunohistochemical approach using the monoclonal antibody PAb1...
Repository :
Europe PubMed Central
Language(s) :
English
M2-AMA do not directly produce ANCA indirect immunofluorescence patterns
Description :
Repository :
Europe PubMed Central
Language(s) :
English