Results
author = "Sandvang, Dorthe"
Novel Streptomycin and Spectinomycin Resistance Gene as a Gene Cassette within a Class 1 Integron Isolated from Escherichia coli
Author(s) :
Sandvang, Dorthe
Description :
The aadA genes, encoding resistance to streptomycin and spectinomycin, have been found as gene cassettes in different gram-negative and gram-positive bacterial species. The present study has revealed the sequence of a new gene, aadA5, integrated as a gene cassette together with the trimethoprim resi...
Repository :
Europe PubMed Central
Language(s) :
English
Class 1 Integrons and Tetracycline Resistance Genes in Alcaligenes, Arthrobacter, and Pseudomonas spp. Isolated from Pigsties and Manured Soil
Description :
The presence of tetracycline resistance (Tcr) genes and class I integrons (in-1), and their ability to cotransfer were investigated in Tcr gram-negative (185 strains) and gram-positive (72 strains) bacteria from Danish farmland and pigsties. The isolates belonged to the groups or species Escherichia...
Repository :
Europe PubMed Central
Language(s) :
English
Epidemiological characteristics of Salmonella Typhimurium isolated from animals and feed in Poland
Description :
Repository :
Research at ASB
Language(s) :
English
In Vivo Development of Quinolone Resistance in Salmonella enterica Serotype Typhimurium DT104
Description :
Salmonella enterica serotype Typhimurium definitive phage type 104 was isolated several times from the same patient over a period of 2 years. The strain developed reduced sensitivity to fluoroquinolones, and a mutation in the gyrA gene that is associated with reduced sensitivity to quinolones was id...
Repository :
Europe PubMed Central
Language(s) :
English
Distribution and Content of Class 1 Integrons in Different Vibrio cholerae O-Serotype Strains Isolated in Thailand
Description :
In this study, 176 clinical and environmental Vibrio cholerae strains of different O serotypes isolated in Thailand from 1982 to 1995 were selected and studied for the presence of class 1 integrons, a new group of genetic elements which carry antibiotic resistance genes. Using PCR and DNA sequencing...
Repository :
Europe PubMed Central
Language(s) :
English
Biological Cost of Single and Multiple Norfloxacin Resistance Mutations in Escherichia coli Implicated in Urinary Tract Infections
Author(s) :
Lindgren, Patricia Komp
,
Marcusson, Linda L.
,
Sandvang, Dorthe
,
Frimodt-Møller, Niels
,
Hughes, Diarmaid
Description :
Resistance to fluoroquinolones in urinary tract infection (UTIs) caused by Escherichia coli is associated with multiple mutations, typically those that alter DNA gyrase and DNA topoisomerase IV and those that regulate AcrAB-TolC-mediated efflux. We asked whether a fitness cost is associated with the...
Repository :
Europe PubMed Central
Language(s) :
English
High Cerebrospinal Fluid (CSF) Penetration and Potent Bactericidal Activity in CSF of NZ2114, a Novel Plectasin Variant, during Experimental Pneumococcal Meningitis▿
Author(s) :
Østergaard, Christian
,
Sandvang, Dorthe
,
Frimodt-Møller, Niels
,
Kristensen, Hans-Henrik
Description :
Plectasin is the first defensin-type antimicrobial peptide isolated from a fungus and has potent activity against gram-positive bacteria. By using an experimental meningitis model, the penetration of plectasin into the cerebrospinal fluid (CSF) of infected and uninfected rabbits and the bactericidal...
Repository :
Europe PubMed Central
Language(s) :
English
Pulsed-Field Gel Electrophoresis Typing of Escherichia coli Strains from Samples Collected before and after Pivmecillinam or Placebo Treatment of Uncomplicated Community-Acquired Urinary Tract Infection in Women
Author(s) :
Ejrnaes, Karen
,
Sandvang, Dorthe
,
Lundgren, Bettina
,
Ferry, Sven
,
Holm, Stig
,
Monsen, Tor
,
Lundholm, Rolf
,
Frimodt-Moller, Niels
Description :
The primary infecting Escherichia coli strains from 156 women with community-acquired uncomplicated urinary tract infection (UTI) randomized to pivmecillinam or placebo and the E. coli strains causing UTI at two follow-up visits were typed using pulsed-field gel electrophoresis (PFGE). In the pivmec...
Repository :
Europe PubMed Central
Language(s) :
English
Polymorphic Mutation Frequencies in Escherichia coli: Emergence of Weak Mutators in Clinical Isolates
Author(s) :
Baquero, María-Rosario
,
Nilsson, Annika I.
,
del Carmen Turrientes, María
,
Sandvang, Dorthe
,
Galán, Juan Carlos
Description :
Polymorphisms in the rifampin resistance mutation frequency (f) were studied in 696 Escherichia coli strains from Spain, Sweden, and Denmark. Of the 696 strains, 23% were weakly hypermutable (4 × 10−8 ≤ f < 4 × 10−7), and 0.7% were strongly hypermutable (f ≥ 4 × 10−7). Weak mutators were apparently ...
Repository :
Europe PubMed Central
Language(s) :
English