Results
author = "Sadzot-Delvaux, Catherine"
Le virus de la varicelle et du zona dans le système nerveux : retraite silencieuse ou guérilla permanente ? Varicella-Zoster virus in the nervous system: silent retreat or permanent guerilla?
Description :
Varicella-zoster virus is a Herpesvirus responsible for three distinct clinical features : chicken pox (varicella), shingles (herpes zoster) and post-zosterian pain (post-herpetic neuralgia). Neurological aspects of these diseases such as complications of chicken pox, viral latency in sensory gan-gl...
Repository :
ORBi (University of Liège)
Language(s) :
French
The role of varicella zoster virus immediate-early proteins in latency and their potential use as components of vaccines
Description :
Varicella zoster virus immediate-early (IE) proteins are intracellular regulators of viral gene expression. Some of them (IE62 and IE63) are found in large amounts in infected cells but are also components of the virion tegument. Several IE and early genes are transcribed during latency, while late ...
Repository :
ORBi (University of Liège)
Language(s) :
English
Varicella-zoster virus IE63, a virion component expressed during latency and acute infection, elicits humoral and cellular immunity
Description :
Varicella-zoster virus (VZV) latency in human dorsal root ganglia is characterized by the transcription of large regions of its genome and by the expression of large amounts of some polypeptides, which are also expressed during lytic cycles. The immediate early 63 protein (IE63) is a virion componen...
Repository :
ORBi (University of Liège)
Language(s) :
English
Le virus de la varicelle et du zona : un alphaherpesvirus pas vraiment comme les autres Varicelle zoster virus, an alphaherpesvirus different from others
Description :
Repository :
ORBi (University of Liège)
Language(s) :
French
The Varicella-Zoster virus IE4 protein: a conserved member of the herpesviral mRNA export factors family and a potential alternative target in antiherpetic therapies
Description :
Repository :
ORBi (University of Liège)
Language(s) :
English
Innate immune response and viral interference strategies developed by Human Herpeviruses
Description :
Repository :
ORBi (University of Liège)
Language(s) :
English
Regions of the varicella-zoster virus open reading frame 63 latency-associated protein important for replication in vitro are also critical for efficient establishment of latency.
Author(s) :
Cohen, Jeffrey I
,
Krogmann, Tammy
,
Bontems, Sébastien
,
Sadzot-Delvaux, Catherine
,
Pesnicak, Lesley
Description :
Varicella-zoster virus (VZV) open reading frame 63 (ORF63) is one of the most abundant transcripts expressed during VZV latency in humans, and ORF63 protein has been detected in human ganglia by several laboratories. Deletion of over 90% of the ORF63 gene showed that the protein is required for effi...
Repository :
ORBi (University of Liège)
Language(s) :
English
Varicella-Zoster virus gene expression in latently infected rat dorsal root ganglia.
Description :
Latent infection of human ganglia with Varicella-Zoster virus (VZV) is characterized by a highly restricted pattern of viral gene expression. To enhance understanding of this process we used in situ hybridization (ISH) in a rat model of VZV latency to examine expression of RNA corresponding to eight...
Repository :
ORBi (University of Liège)
Language(s) :
English
Varicella-zoster virus induces apoptosis in cell culture
Author(s) :
Sadzot-Delvaux, Catherine
,
Thonard, P.
,
Schoonbroodt, Sonia
,
Piette, Jacques
,
Rentier, Bernard
Description :
Apoptosis is an active mechanism of cell death which can be initiated in response to various stimuli including virus infections. In this work, we demonstrate that lytic infection by varicella-zoster virus (VZV), a human herpesvirus, is characterized by nuclear fragmentation of DNA into oligonucleoso...
Repository :
ORBi (University of Liège)
Language(s) :
English
Varicella-zoster virus IE63 protein phosphorylation by roscovitine-sensitive cyclin-dependent kinases modulates its cellular localization and activity.
Author(s) :
Habran, Lionel
,
Bontems, Sébastien
,
Di Valentin, Emmanuel
,
Sadzot-Delvaux, Catherine
,
Piette, Jacques
Description :
During the first stage of Varicella-Zoster virus (VZV) infection, IE63 (immediate early 63 protein) is mostly expressed in the nucleus and also slightly in the cytoplasm, and during latency, IE63 localizes in the cytoplasm quite exclusively. Because phosphorylation is known to regulate various cellu...
Repository :
ORBi (University of Liège)
Language(s) :
English