Results
author = "Sabin, CA"
Predictors of hypertension and changes of blood pressure in HIV-infected patients
Author(s) :
Thiebaut, R
,
El-Sadr, WM
,
Friis-Moller, N
,
Rickenbach, M
,
Reiss, P
,
Monforte, AD
,
Morfeldt, L
,
Fontas, E
,
Kirk, O
,
De Wit, S
Description :
Objective: We assessed predictors of changes in systolic (SBP) and diastolic (DBP) blood pressure during follow-up and of the development of hypertension in HIV-infected individuals.Methods: International cohort collaborative study (D:A:D) of established prospective cohorts of HIV-1-infected patient...
Repository :
UCL Eprints
Language(s) :
Undetermined
The use of the Framingham equation to predict myocardial infarctions in HIV-infected patients: comparison with observed events in the D : A : D Study
Author(s) :
Law, MG
,
Friis-Moller, N
,
El-Sadr, WM
,
Weber, R
,
Reiss, P
,
Monforte, AD
,
Thiebaut, R
,
Morfeldt, L
,
De Wit, S
,
Pradier, C
Description :
Background The D:A:D (Data Collection on Adverse Events of Anti-HIV Drugs) Study, a prospective observational study on a cohort of 23 468 patients with HIV infection, indicated that the incidence of myocardial infarction (MI) increased by 26% per year of exposure to combination antiretroviral treatm...
Repository :
UCL Eprints
Language(s) :
Undetermined
Prognosis of HIV-1-infected patients starting highly active antiretroviral therapy: a collaborative analysis of prospective studies
Author(s) :
Egger, M
,
May, M
,
Chene, G
,
Phillips, AN
,
Ledergerber, B
,
Dabis, F
,
Costagliola, D
,
Monforte, AD
,
de Wolf, F
,
Reiss, P
Description :
Background Insufficient data are available from single cohort studies to allow estimation of the prognosis of HIV-1 infected, treatment-naive patients who start highly active antiretroviral therapy (HAART). The ART Cohort Collaboration, which includes 13 cohort studies from Europe and North America,...
Repository :
UCL Eprints
Language(s) :
Undetermined
Cardiovascular disease risk factors in HIV patients - association with antiretroviral therapy. Results from the DAD study
Author(s) :
Friis-Moller, N
,
Weber, R
,
Reiss, P
,
Thiebaut, R
,
Kirk, O
,
Monforte, AD
,
Pradier, C
,
Morfeldt, L
,
Mateu, S
,
Law, M
,
El-Sadr, W
Description :
Objective: To determine the prevalence of risk factors for cardiovascular disease (CVD) among HIV-infected persons, and to investigate any association between such risk factors, stage of HIV disease, and use of antiretroviral therapies.Design: Baseline data from 17 852 subjects enrolled in DAD, a pr...
Repository :
UCL Eprints
Language(s) :
Undetermined
Increased duration of viral suppression is associated with lower viral rebound rates in patients with previous treatment failures
Author(s) :
Benzie, AA
,
Bansi, LK
,
Sabin, CA
,
Portsmouth, S
,
Hill, T
,
Johnson, M
,
Gilson, R
,
Easterbrook, P
,
Gazzard, B
,
Fisher, M
Description :
Objective: We investigated whether the rate of viral rebound decreases with increasing duration of viral suppression and, if so, whether rebound rates in patients previously failing antiretroviral regimens ultimately decline to levels as low as those seen in patients who have never experienced virol...
Repository :
UCL Eprints
Language(s) :
Undetermined
Changes in outcome of persons initiating highly active antiretroviral therapy at a CD4 count less than 50 cells/mm(3)
Author(s) :
Porter, K
,
Walker, S
,
Hill, T
,
Anderson, J
,
Leen, C
,
Johnson, M
,
Gazzard, B
,
Walsh, J
,
Fisher, M
,
Orkin, C
,
Schwenk, A
,
Gilson, R
Description :
Background: Although HIV treatment guidelines recommend highly active antiretroviral therapy (HAART) initiation before reaching a CD4 count of 200 cells/mm(3), many people in resource-rich settings, and a substantial proportion in resource-limited settings, present at levels <50 cells/mm(3).Methods:...
Repository :
UCL Eprints
Language(s) :
Undetermined
Diabetes Mellitus, Preexisting Coronary Heart Disease, and the Risk of Subsequent Coronary Heart Disease Events in Patients Infected With Human Immunodeficiency Virus The Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D Study)
Author(s) :
Worm, SW
,
De Wit, S
,
Weber, R
,
Sabin, CA
,
Reiss, P
,
El-Sadr, W
,
Monforte, AD
,
Kirk, O
,
Fontas, E
,
Dabis, F
,
Law, MG
,
Lundgren, JD
Description :
Background-Although guidelines in individuals not infected with the human immunodeficiency virus (HIV) consider diabetes mellitus (DM) to be a coronary heart disease (CHD) equivalent, there is little information on its association with CHD in those infected with HIV. We investigated the impact of DM...
Repository :
UCL Eprints
Language(s) :
Undetermined
Targeting C-reactive protein for the treatment of cardiovascular disease
Author(s) :
Pepys, MB
,
Hirschfield, GM
,
Tennent, GA
,
Gallimore, JR
,
Kahan, MC
,
Bellotti, V
,
Hawkins, PN
,
Myers, RM
,
Smith, MD
,
Polara, A
Description :
Complement-mediated inflammation exacerbates the tissue injury of ischaemic necrosis in heart attacks and strokes, the most common causes of death in developed countries. Large infarct size increases immediate morbidity and mortality and, in survivors of the acute event, larger non-functional scars ...
Repository :
UCL Eprints
Language(s) :
Undetermined
Predicting the risk of cardiovascular disease in HIV-infected patients: the Data collection on Adverse Effects of Anti-HIV Drugs Study
Author(s) :
Friis-Moller, N
,
Thiebaut, R
,
Reiss, P
,
Weber, R
,
Monforte, AD
,
De Wit, S
,
El-Sadr, W
,
Fontas, E
,
Worm, S
,
Kirk, O
,
Phillips, A
Description :
Aims HIV-infected patients receiving combination antiretroviral therapy may experience metabolic complications, potentially increasing their risk of cardiovascular diseases (CVDs). Furthermore, exposures to some antiretroviral drugs seem to be independently associated with increased CVD risk. We aim...
Repository :
UCL Eprints
Language(s) :
Undetermined
Combination antiretroviral therapy and the risk of myocardial infarction
Author(s) :
Friis-Moller, N
,
Sabin, CA
,
Weber, R
,
d'Arminio Monforte, A
,
El-Sadr, WM
,
Reiss, P
,
Thiebaut, R
,
Morfeldt, L
,
De Wit, S
Description :
BACKGROUND: It remains controversial whether exposure to combination antiretroviral treatment increases the risk of myocardial infarction. METHODS: In this prospective observational study, we enrolled 23,468 patients from 11 previously established cohorts from December 1999 to April 2001 and collect...
Repository :
UCL Eprints
Language(s) :
Undetermined