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author = "Roffel, A. F."
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Found 3 documents, displaying page 1 of 1

No evidence for a role of muscarinic M2 receptors in functional antagonism in bovine trachea.

Author(s) : Roffel, A. F. , Meurs, H. , Elzinga, C. R. , Zaagsma, J.
Description : 1. The functional antagonism between methacholine- or histamine-induced contraction and beta-adrenoceptor-mediated relaxation was evaluated in bovine tracheal smooth muscle in vitro. In addition, the putative contribution of muscarinic M2 receptors mediating inhibition of beta-adrenoceptor-induced b...
Repository : Europe PubMed Central
Language(s) : English

Characterization of the muscarinic receptor subtype involved in phosphoinositide metabolism in bovine tracheal smooth muscle.

Author(s) : Roffel, A. F. , Meurs, H. , Elzinga, C. R. , Zaagsma, J.
Description : 1. The muscarinic receptor subtype involved in the methacholine-induced enhancement of phosphoinositide metabolism in bovine tracheal smooth muscle was identified by using the M2-selective antagonist AF-DX 116 and the M3-selective antagonist 4-diphenylacetoxy-N-methylpiperidine (4-DAMP) methobromide...
Repository : Europe PubMed Central
Language(s) : English

Characterization of presynaptic vascular muscarinic receptors inhibiting endogenous noradrenaline overflow in the portal vein of the freely moving rat.

Author(s) : Remie, R. , Coppes, R. P. , Meurs, H. , Roffel, A. F. , Zaagsma, J.
Description : 1. In the portal vein of permanently cannulated, freely moving, unanaesthetized rats, methacholine (MCh) is able to inhibit the electrically-evoked endogenous noradrenaline (NA) overflow. This inhibition is mediated by presynaptic inhibitory muscarinic heteroreceptors. 2. By use of pirenzepine, 4-di...
Repository : Europe PubMed Central
Language(s) : English
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Found 3 documents, displaying page 1 of 1