Results
author = "Rocha, Miguel"
Uncovering mechanisms underlying the Escherichia coli stringent response : application of text mining approaches to identify meaningful relations in text documents
Author(s) :
Carneiro, S.
,
Lourenço, Anália
,
Carreira, Rafael
,
Rocha, Miguel
,
Ferreira, E. C.
,
Rocha, I.
Description :
Repository :
RepositóriUM - University of Minho Institutional Repository
Language(s) :
English
The @Note biomedical text mining workbench
Author(s) :
Lourenço, Anália
,
Carreira, Rafael
,
Carneiro, S.
,
Maia, Paulo
,
Ferreira, E. C.
,
Rocha, Miguel
,
Rocha, I.
Description :
Repository :
RepositóriUM - University of Minho Institutional Repository
Language(s) :
English
Network analysis of an integrated metabolic/regulatory model of Escherichia coli
Author(s) :
Carneiro, S.
,
Lourenço, Anália
,
Mendes, Rui
,
Rocha, Miguel
,
Ferreira, E. C.
,
Rocha, I.
Description :
Repository :
RepositóriUM - University of Minho Institutional Repository
Language(s) :
English
Human Immunoglobulin G2 (IgG2) and IgG4, but Not IgG1 or IgG3, Protect Mice against Cryptococcus neoformans Infection▿
Author(s) :
Beenhouwer, David O.
,
Yoo, Esther M.
,
Lai, Chun-Wei
,
Rocha, Miguel A.
,
Morrison, Sherie L.
Description :
The encapsulated yeast Cryptococcus neoformans is a significant cause of meningitis and death in patients with AIDS. Some murine monoclonal antibodies (MAbs) against the glucuronoxylomannan (GXM) component of the C. neoformans capsular polysaccharide can prolong the lives of infected mice, while oth...
Repository :
Europe PubMed Central
Language(s) :
English
Natural computation meta-heuristics for the in silico optimization of microbial strains
Author(s) :
Rocha, Miguel
,
Maia, Paulo
,
Mendes, Rui
,
Pinto, José P
,
Ferreira, Eugénio C
,
Nielsen, Jens
,
Patil, Kiran Raosaheb
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Semantic annotation of biological concepts interplaying microbial cellular responses
Author(s) :
Carreira, Rafael
,
Carneiro, Sónia
,
Pereira, Rui
,
Rocha, Miguel
,
Rocha, Isabel
,
Ferreira, Eugénio C
,
Lourenço, Anália
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Natural computation meta-heuristics for the in silico optimization of microbial strains
Author(s) :
Rocha, Miguel
,
Maia, Paulo
,
Mendes, Rui
,
Pinto, José
,
Ferreira, Euqénio
,
Nielsen, Jens
,
Patil, Kiran Raosaheb
,
Rocha, Isabel
Description :
Background: One of the greatest challenges in Metabolic Engineering is to develop quantitative models and algorithms to identify a set of genetic manipulations that will result in a microbial strain with a desirable metabolic phenotype which typically means having a high yield/productivity. This cha...
Repository :
ORBIT The DTU Research Database
Language(s) :
English
Modeling formalisms in Systems Biology
Author(s) :
Machado, Daniel
,
Costa, Rafael S.
,
Rocha, Miguel
,
Ferreira, Eugenio C.
,
Tidor, Bruce
,
Rocha, Isabel
Description :
Systems Biology has taken advantage of computational tools and high-throughput experimental data to model several biological processes. These include signaling, gene regulatory, and metabolic networks. However, most of these models are specific to each kind of network. Their interconnection demands ...
Repository :
DSpace@MIT - MIT's online institutional repository
Language(s) :
English
A critical review on modelling formalisms and simulation tools in computational biosystems
Author(s) :
Machado, Daniel
,
Costa, Rafael S.
,
Rocha, Miguel
,
Rocha, Isabel
,
Tidor, Bruce
,
Ferreira, Eugenio C.
Description :
Integration of different kinds of biological processes is an ultimate goal for whole-cell modelling. We briefly review modelling formalisms that have been used in Systems Biology and identify the criteria that must be addressed by an integrating framework capable of modelling, analysing and simulati...
Repository :
DSpace@MIT - MIT's online institutional repository
Language(s) :
English
OptFlux: an open-source software platform for in silico metabolic engineering
Author(s) :
Rocha Isabel
,
Maia Paulo
,
Evangelista Pedro
,
Vilaça Paulo
,
Soares Simão
,
Pinto José P
,
Nielsen Jens
,
Patil Kiran R
Description :
Abstract
Background
Over the last few years a number of methods have been proposed for the phenotype simulation of microorganisms under different environmental and genetic conditions. These have been used as the basis to support the discovery of successful genetic modifications of t...
Repository :
DOAJ-Articles
Language(s) :
English