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author = "Rizzuto, R"
<< < 2 3 4 5 6

Found 52 documents, displaying page 6 of 6

Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA

Author(s) : Poncet, D , Pauleau, AL , Szabadkai, G , Vozza, A , Scholz, SR , Le Bras, M , Briere, JJ , Jalil, A , Le Moigne, R , Brenner, C
Description : Replication of human cytomegalovirus (CMV) requires the expression of the viral mitochondria localized inhibitor of apoptosis (vMIA). vMIA inhibits apoptosis by recruiting Bax to mitochondria, resulting in its neutralization. We show that vMIA decreases cell size, reduces actin polymerization, and i...
Repository : UCL Eprints
Language(s) : Undetermined

Regulation of autophagy by cytoplasmic p53

Author(s) : Tasdemir, E , Maiuri, MC , Galluzzi, L , Vitale, I , Djavaheri-Mergny, M , D'Amelio, M , Criollo, A , Morselli, E , Zhu, CL , Harper, F
Description : Multiple cellular stressors, including activation of the tumour suppressor p53, can stimulate autophagy. Here we show that knockout, knockdown or pharmacological inhibition of p53 can induce autophagy in human, mouse and nematode cells. Enhanced autophagy improved the survival of p53-deficient cance...
Repository : UCL Eprints
Language(s) : Undetermined
<< < 2 3 4 5 6

Found 52 documents, displaying page 6 of 6