flag flag  

author = "Rizzuto, A"

Found 158 documents, displaying page 1 of 16

Shaping the Research Infrastructures landscape in EU

Author(s) : Rizzuto, Carlo
Description : This presentation was given in the opening plenary session and focused on Pan-EU Research Infrastructures and related main issues and provided also an overview on the ESFRI mission.
Repository : BELIEF e-Infrastructure Digital Library
Language(s) : English

Living longer than expected : protective and risk factors related to human longevity

Author(s) : Rizzuto, Debora
Description : The scientific community has become increasingly interested in understanding what lies behind the continuing extension of the human lifespan. The main aim of this thesis was to better understand the association between health status, lifestyle, genetic factors and survival in advanced age. Data used...
Repository : Publications from Karolinska Institutet
Language(s) : English

Calcium mobilization from mitochondria in synaptic transmitter release

Author(s) : Rizzuto, Rosario
Description : Mitochondria can rapidly accumulate and release Ca2+ upon cell stimulation. A paper by Yang and coworkers in this issue reports an unusual form of synaptic potentiation, dependent on Ca2+ release from mitochondria through the Na+/Ca2+ exchanger and triggered by Na+ entry through voltage-gated channe...
Repository : Europe PubMed Central
Language(s) : English

Dodecahedric mutually supported element space structure experimental and numerical modelling investigation: discussion of results

Author(s) : RIZZUTO, Joseph P.
Description : Mutually supported elements (MSE) arranged in closed circuits can create single module lattice type space structures. These may be connected to one another in networks to generate much larger space structures. To broaden the understanding of the structural behaviour of bolted MSE structures an inves...
Repository : RiuNet : repositorio institucional de la Universitat Politècnica de Valencia
Language(s) : English

Participation of endoplasmic reticulum and mitochondrial calcium handling in apoptosis: more than just neighborhood?

Author(s) : Szabadkai, G , Rizzuto, R
Description : Over the past few years, extensive progress has been made in elucidating the role of calcium in the signaling of apoptosis. This has led to the characterization of calcium's role in the induction of apoptosis and in the regulation of effector proteases. In this review, we attempt to summarize the cu...
Repository : UCL Eprints
Language(s) : Undetermined

Chaperones as parts of organelle networks

Author(s) : Szabadkai, G , Rizzuto, R
Description : The efficiency, divergence and specificity of virtually all intracellular metabolic and signalling pathways largely depend on their compartmentalized organization. A corollary of the requirement of compartmentalization is the dynamic structural partition of the intracellular space by endomembrane sy...
Repository : UCL Eprints
Language(s) : Undetermined

Respect in Clinical Practice

Author(s) : RIZZUTO, ANA-MARIA
Description : Respect is naturally presumed to be a component of the therapeutic relationship. Therapists, however, need to go beyond the everyday understanding of respect and be prepared to provide a dimension that we do not expect to find in other human relations.
Repository : Europe PubMed Central
Language(s) : English

Mitochondrial Ca2+ uptake requires sustained Ca2+ release from the endoplasmic reticulum

Description : We analyzed the role of inositol 1,4,5-trisphosphate-induced Ca2+ release from the endoplasmic reticulum (ER) (i) in powering mitochondrial Ca2+ uptake and (ii) in maintaining a sustained elevation of cytosolic Ca2+ concentration ([Ca2+](c)). For this purpose, we expressed in HeLa cells aequorin-bas...
Repository : UCL Eprints
Language(s) : Undetermined

The Mitochondrial Antioxidants MitoE(2) and MitoQ(10) Increase Mitochondrial Ca2+ Load upon Cell Stimulation by Inhibiting Ca2+ Efflux from the Organelle

Author(s) : Leo, S , Szabadkai, G , Rizzuto, R
Description : Mitochondrial reactive oxygen species (ROS) production is recognized as a major pathogenic event in a number of human diseases, and mitochondrial scavenging of ROS appears a promising therapeutic approach. Recently, two mitochondrial antioxidants have been developed; conjugating alpha-tocopherol and...
Repository : UCL Eprints
Language(s) : Undetermined

Modulation of intracellular Ca2+ signalling in HeLa cells by the apoptotic cell death enhancer PK11195

Description : 1-(2-Chlorophenyl-N-methylpropyl)-3-isoquinolinecarboxamide (PK11195) is a proven enhancer of apoptotic cell death in a variety of cellular models. This effect is independent of its established cellular target, the mitochondrial benzodiazepine receptor (mBzR), since it is able to promote cell death ...
Repository : UCL Eprints
Language(s) : Undetermined

Found 158 documents, displaying page 1 of 16