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author = "Rentier-Delrue, Françoise"
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Found 4 documents, displaying page 2 of 1

The antiangiogenic factor 16K human prolactin induces caspase-dependent apoptosis by a mechanism that requires activation of nuclear factor-kappa B

Author(s) : Tabruyn, Sébastien , Sorlet, C. M. , Rentier-Delrue, Françoise , Bours, Vincent , Weiner, R. I. , Martial, Joseph , Struman, Ingrid
Description : We have previously shown that the 16-kDa N-terminal fragment of human prolactin (16K hPRL) has antiangiogenic properties, including the ability to induce apoptosis in vascular endothelial cells. Here, we examined whether the nuclear factor-kappaB (NF-kappaB) signaling pathway was involved in mediati...
Repository : ORBi (University of Liège)
Language(s) : English

Molecular targeting of antiangiogenic factor 16K hPRL inhibits oxygen-induced retinopathy in mice

Author(s) : Pan, H. , Nguyen, Ngoc-Quynh-Nhu , Yoshida, H. , Bentzien, F. , Shaw, L. C. , Rentier-Delrue, Françoise , Martial, Joseph
Description : PURPOSE. To examine the ability and mechanism of the 16 kDa N-terminal fragment of human prolactin (16K hPRL) in the inhibition of abnormal retinal neovascularization. METHODS. The 16K hPRL-encoding sequence was inserted into an adenoviral vector (16K-Ad). Western blot analysis verified the expressi...
Repository : ORBi (University of Liège)
Language(s) : English

Identification and modulation of a growth hormone-binding protein in rainbow trout (Oncorhynchus mykiss) plasma during seawater adaptation.

Author(s) : Sohm, F. , Manfroid, Isabelle , Pezet, A. , Rentier-Delrue, Françoise , Rand-Weaver, M. , Kelly, P. A. , Boeuf, G. , Postel-Vinay, M. C.
Description : A soluble protein that specifically bound 125I-human growth hormone (hGH) was identified in rainbow trout plasma, using HPLC-gel filtration. The binding affinity of the protein for hGH was 1.2 x 10(9)M-1. 125I-rainbow trout GH (tGH) was also able to bind to the protein albeit with a lower affinity (...
Repository : ORBi (University of Liège)
Language(s) : English

Prolactin/growth hormone–derived antiangiogenic peptides highlight a potential role of tilted peptides in angiogenesis

Author(s) : Nguyen, Ngoc-Quynh-Nhu , Tabruyn, Sebastien P. , Lins, Laurence , Lion, Michelle , Cornet, Anne M. , Lair, Florence
Description : Angiogenesis is a crucial step in many pathologies, including tumor growth and metastasis. Here, we show that tilted peptides exert antiangiogenic activity. Tilted (or oblique-oriented) peptides are short peptides known to destabilize membranes and lipid cores and characterized by an asymmetric dist...
Repository : Europe PubMed Central
Language(s) : English
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Found 4 documents, displaying page 2 of 1