Results
author = "RUMMENS, Jean-Luc"
Ultrastructure of transplanted mesenchymal stem cells after acute myocardial infarction
Description :
Repository :
Document Server@UHasselt
Language(s) :
English
Cardiac stem cells in the real world
Description :
Repository :
Document Server@UHasselt
Language(s) :
English
Memory CD4(+)CD127(high) T cells from patients with multiple sclerosis produce IL-17 in response to myelin antigens
Description :
Myelin-reactive T helper-17 cells are implicated in the pathogenesis of multiple sclerosis (MS). Here, we analyzed the reactivity of peripheral naive and memory conventional CD4(+)CD127(high) T cells (Tconv) of MS patients and healthy controls (HC) towards myelin basic protein (MBP), myelin oligoden...
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Document Server@UHasselt
Language(s) :
English
Natural naive regulatory T cell development and function are disturbed in multiple sclerosis patients
Description :
Background: Myelin-reactive T cells may play a pathogenic role in
multiple sclerosis (MS). We and others have shown that regulatory
CD4+CD25+FOXP3+CD127low T cells (Tregs) are functionally disturbed
in relapsing-remitting (RR) MS patients but not in secondary
progressive (SP) MS patients. Objective:...
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Document Server@UHasselt
Language(s) :
English
Haplotype 4 of the multiple sclerosis-associated interleukin-7 receptor alpha gene influences the frequency of recent thymic emigrants.
Author(s) :
BROUX, Bieke
,
HELLINGS, Niels
,
VENKEN, Koen
,
RUMMENS, Jean-Luc
,
Hensen, Karen
,
VAN WIJMEERSCH, Bart
,
STINISSEN, Piet
Description :
The receptor for the homeostatic T cell cytokine interleukin-7 (IL-7Ralpha) has recently shown genetic association to multiple sclerosis (MS). To investigate the functional contribution of IL-7Ralpha polymorphisms to the pathogenesis of MS, we correlated the IL-7Ralpha haplotypes with different T ce...
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Document Server@UHasselt
Language(s) :
English
Suppressed increase in blood endothelial progenitor cell content as result of single exhaustive exercise bout in male revascularised coronary artery disease patients.
Author(s) :
HANSEN, Dominique
,
Daniels, Annick
,
Hensen, Karen
,
HENDRIKX, Marc
,
Berger, Jan
,
DENDALE, Paul
,
Koninckx, Remco
,
RUMMENS, Jean-Luc
Description :
Repository :
Document Server@UHasselt
Language(s) :
English
Reduced number of blood circulating foxp3+CD25highCD4+regulatory T cells and a decreased foxp3 expression at the single-cell level in patients with relapsing-remitting multiple sclerosis
Author(s) :
VENKEN, Koen
,
HELLINGS, Niels
,
SOMERS, Veerle
,
MEUWISSEN, Pieter
,
THEWISSEN, Marielle
,
Hensen, Karen
,
RUMMENS, Jean-Luc
Description :
CD4+CD25high regulatory T cells (Tregs) of patients with relapsing-remitting (RR), but not secondary-progressive (SP) multiple sclerosis (MS), show a reduced suppressive function and FoxP3 mRNA expression. In this study we analyzed FoxP3 protein expression by means of flow cytometry in PBMC of 55 RR...
Repository :
Document Server@UHasselt
Language(s) :
English
A CFSE based assay for measuring CD4(+)CD25(+) regulatory T cell mediated suppression of auto-antigen specific and polyclonal T cell responses
Author(s) :
VENKEN, Koen
,
THEWISSEN, Marielle
,
HELLINGS, Niels
,
SOMERS, Veerle
,
Hensen, Karen
,
STINISSEN, Piet
,
RUMMENS, Jean-Luc
Description :
CD4(+)CD25(+) regulatory T cells (Tregs) are considered to play a key role as suppressors of immune inediated reactions. The analysis of Treg function in patients with autoimmune, allergic or oncogenic diseases has emerged over the past years. In the present study we describe a CFSE based protocol t...
Repository :
Document Server@UHasselt
Language(s) :
English
Natural naive CD4(+)CD25(+)CD127(low) regulatory T cell (Treg) development and function are disturbed in multiple sclerosis patients: Recovery of memory treg homeostasis during disease progression
Author(s) :
VENKEN, Koen
,
HELLINGS, Niels
,
BROEKMANS, Tom
,
Hensen, K.
,
RUMMENS, Jean-Luc
,
STINISSEN, Piet
Description :
Patients with relapsing-remitting multiple sclerosis (RR-MS) show a suboptimal CD4(+)CD25(+) regulatory T cell (Treg) function, whereas no Treg alterations are observed in secondary progressive MS (SP-MS) patients. To clarify the difference in Treg activity between early and chronic disease stages i...
Repository :
Document Server@UHasselt
Language(s) :
English
Natural naive regulatory T cell development and function are disturbed in multiple sclerosis patients
Author(s) :
Venken, Koen
,
Hellings, Niels
,
Broekmans, Tom
,
Hensen, Karen
,
Rummens, Jean-Luc
,
Stinissen, Piet
Description :
Repository :
Document Server@UHasselt
Language(s) :
English