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author = "Paquot, Nicolas"

Found 72 documents, displaying page 5 of 8

Le medicament du mois. L'insuline detemir (Levemir) [Insulin detemir (Levemir)]

Description : Insulin detemir (Levemir) is a soluble long acting human insulin analogue acylated with a 14-carbon fatty acid. The fatty acid modification allows insulin detemir to reversibly bind to albumin, thereby providing slow absorption and a prolonged metabolic effect (up to 24 hours) with low variability. ...
Repository : ORBi (University of Liège)
Language(s) : French

L'hyperglycemie post-prandiale. I. Physiopathologie, consequences cliniques et approaches dietetiques. Postprandial hyperglycemia. I. Physiopathology, clinical consequences and dietary management

Description : Postprandial hyperglycaemia depends on the amount and type of ingested carbohydrates and/or the degree of inhibition of hepatic glucose output following a meal. The kinetics of carbohydrate absorption is directly influenced by the type of food (carbohydrates with variable glycaemic indices, fibre co...
Repository : ORBi (University of Liège)
Language(s) : French

L'hyperglycemie post-prandiale. II. Approches therapeutiques medicamenteuses. Postprandial hyperglycemia. II. Pharmacological approaches

Description : Besides dietary approaches, various pharmacological means have been recently developed in order to better control postprandial hyperglycaemia. This objective may be obtained: 1) by slowing down the intestinal absorption of carbohydrates; 2) by insuring a better insulin priming soon after the meal; a...
Repository : ORBi (University of Liège)
Language(s) : French

Inhibition des recepteurs CB1 et metabolisme du glucose: rimonabant dans le diabete de type 2. CB1 receptor inhibition and glucose metabolism: role of rimonabant in type 2 diabetes

Description : Endocannabinoid system is overactivated in individuals with abdominal obesity. CBI receptors, first individualized in the brain, are also expressed in the adipocyte, the skeletal muscle, the liver, the gut, and the pancreas. Their blockade improves glucose tolerance and lipid profile, thanks increas...
Repository : ORBi (University of Liège)
Language(s) : French

Bariatric surgery in patients with Type 2 diabetes: benefits, risks, indications and perspectives.

Description : Obesity plays a key role in the pathophysiology of type 2 diabetes (T2DM), and weight loss is a major objective, although difficult to achieve with medical treatments. Bariatric surgery has proven its efficacy in obtaining marked and sustained weight loss, and is also associated with a significant i...
Repository : ORBi (University of Liège)
Language(s) : English

La vignette thérapeutique de l'étudiant. Prise en charge d'une personne obèse avec syndrome métabolique Management of an obese person with metabolic syndrome

Description : The management of an obese person requires a careful evaluation first, a multidisciplinary approach and a stepwise therapeutic strategy. The latter should favour lifestyle modifications, eventually the use pharmacological agents in good responders, and reserve bariatric surgery to well selected case...
Repository : ORBi (University of Liège)
Language(s) : French

Sujets de poids normal «métaboliquement obèses» et sujets obèses «métaboliquement sains»

Description : Les relations entre poids corporel et anomalies métaboliques ne sont pas univoques. Ainsi, il existe des personnes non obèses métaboliquement anormales (MONW), rarement dépistées en raison d’un poids corporel faussement rassurant, et, à l’inverse, des sujets métaboliquement sains bien qu’ils soient ...
Repository : ORBi (University of Liège)
Language(s) : French

Les incretinomimetiques et incretinopotentiateurs dans le traitement du diabete de type 2. [Incretin mimetics and incretin enhancers for the treatment of type 2 diabetes]

Description : Glucagon-like peptide-1 (GLP-1) is a gut hormone secreted in response to a meal ingestion, which is rapidly degraded by a specific enzyme, dipeptidylpeptidase-4 (DPP-4). It enhances insulin secretion in a glucose-dependent manner, inhibits glucagon secretion, retards gastric emptying,... Two pharmac...
Repository : ORBi (University of Liège)
Language(s) : French

Fructose and metabolic diseases: new findings, new questions.

Description : There has been much concern regarding the role of dietary fructose in the development of metabolic diseases. This concern arises from the continuous increase in fructose (and total added caloric sweeteners consumption) in recent decades, and from the increased use of high-fructose corn syrup (HFCS) ...
Repository : ORBi (University of Liège)
Language(s) : English

Found 72 documents, displaying page 5 of 8