flag flag  

author = "Nordström, K"

Found 42 documents, displaying page 1 of 5

Random replication of the stringent plasmid R1 in Escherichia coli K-12.

Description : The R-factor R1 is present in a low number of copies per genome (near unity, so-called stringent control of replication). The replication of R1 was studied in a density-shift experiment. One generation after the shift about 20% of the R1 copies had not replicated, whereas about 20% had replicated at...
Repository : Europe PubMed Central
Language(s) : English

Plasmid incompatibility and control of replication: copy mutants of the R-factor R1 in Escherichia coli K-12.

Author(s) : Uhlin, B E , Nordström, K
Description : Plasmid incompatibility was studied in Escherichia coli K-12. By double-antibiotic selection, clones were constructed that carried the two R-factors R1 and R100, both belonging to the compatibility group FII. After release of the selection pressure, each of the two plasmids was lost at the same rate...
Repository : Europe PubMed Central
Language(s) : English

Effects of streptomycin and novobiocin on Staphylococcus aureus gene expression.

Author(s) : Nordström, K , Lindberg, M
Description : Streptomycin and novobiocin induced production of protein A and inhibited production of alpha- and beta-hemolysins in mutants of Staphylococcus aureus strains RN450 and RN1 resistant to these antibiotics. Streptomycin, but not novobiocin, also inhibited propagation of bacteriophages of serological g...
Repository : Europe PubMed Central
Language(s) : English

Replication of R-factor R1 in Scherichia coli K-12 at different growth rates.

Author(s) : Engberg, B , Nordström, K
Description : The R-factor R1drd-19 mediates resistance to beta-lactam antibiotics via a beta-lactamase. A strain of Escherichia coli K-12 carrying R1drd-19 was grown at different growth rates by using different carbon sources. The specific rate of production of the R1 beta-lactamase increased linearly with the g...
Repository : Europe PubMed Central
Language(s) : English

Preferential inhibition of plasmid replication in vivo by altered DNA gyrase activity in Escherichia coli.

Author(s) : Uhlin, B E , Nordström, K
Description : The thermosensitive growth phenotype exerted by runaway-mutant plasmids was suppressed by sublethal doses of the DNA gyrase inhibitors novobiocin or nalidixic acid, although the latter drug was less efficient. A novobiocin-resistant gyrB mutant Escherichia coli strain prevented expression of the run...
Repository : Europe PubMed Central
Language(s) : English

Clustering versus random segregation of plasmids lacking a partitioning function : a plasmid paradox

Author(s) : Nordström, K. , Gerdes, K.
Description :
Repository : Research at ASB
Language(s) : English

Control of replication of plasmid R1: the duplex between the antisense RNA, CopA, and its target, CopT, is processed specifically in vivo and in vitro by RNase III.

Description : The replication frequency of IncFII plasmids is regulated through the availability of a rate-limiting protein, RepA. The synthesis of this protein is controlled post-transcriptionally by a small antisense RNA, CopA, which binds to the leader region of the RepA mRNA (CopT). In this communication we r...
Repository : Europe PubMed Central
Language(s) : English

Control of replication of plasmid R1: structures and sequences of the antisense RNA, CopA, required for its binding to the target RNA, CopT.

Description : The replication frequency of plasmid R1 is determined by the availability of the RepA protein, which acts at the origin of replication to promote initiation. Synthesis of RepA is negatively regulated both at the transcriptional and post-transcriptional levels. Post-transcriptional control is exerted...
Repository : Europe PubMed Central
Language(s) : English

The cox protein of bacteriophage P2 inhibits the formation of the repressor protein and autoregulates the early operon.

Description : The cox gene is the first gene of the early operon of bacteriophage P2. The early promoter Pe and the repressor promoter Pc are located close to each other and in such a way that their transcripts have opposite polarity and show an overlap of about 30 nucleotides. The expression of the early operon ...
Repository : Europe PubMed Central
Language(s) : English

Replication control of plasmid R1: RepA synthesis is regulated by CopA RNA through inhibition of leader peptide translation.

Description : The replication frequency of plasmid R1 is post-transcriptionally controlled by an antisense RNA, CopA, that binds to the leader region in the RepA mRNA, CopT, and ultimately inhibits the synthesis of the replication initiator protein RepA. We present results demonstrating that CopA controls RepA sy...
Repository : Europe PubMed Central
Language(s) : English

Found 42 documents, displaying page 1 of 5