Results
author = "McGuffog, L"
Genetic Variation at 9p22.2 and Ovarian Cancer Risk for BRCA1 and BRCA2 Mutation Carriers
Author(s) :
Ramus, SJ
,
Kartsonaki, C
,
Gayther, SA
,
Pharoah, PDP
,
Sinilnikova, OM
,
Beesley, J
,
Chen, XQ
,
McGuffog, L
,
Healey, S
,
Couch, FJ
Description :
Background Germline mutations in the BRCA1 and BRCA2 genes are associated with increased risks of breast and ovarian cancers. Although several common variants have been associated with breast cancer susceptibility in mutation carriers, none have been associated with ovarian cancer susceptibility. A ...
Repository :
UCL Eprints
Language(s) :
Undetermined
Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction
Author(s) :
Antoniou, AC
,
Beesley, J
,
McGuffog, L
,
Sinilnikova, OM
,
Healey, S
,
Neuhausen, SL
,
Ding, YC
,
Rebbeck, TR
,
Weitzel, JN
Description :
The known breast cancer susceptibility polymorphisms in FGFR2, TNRC9/TOX3, MAP3K1, LSP1, and 2q35 confer increased risks of breast cancer for BRCA1 or BRCA2 mutation carriers. We evaluated the associations of 3 additional single nucleotide polymorphisms (SNPs), rs4973768 in SLC4A7/NEK10, rs6504950 i...
Repository :
UCL Eprints
Language(s) :
Undetermined
Breast cancer risk and 6q22.33: combined results from breast cancer association consortium and consortium of investigators on modifiers of BRCA1/2
Author(s) :
Kirchhoff, T.
,
Gaudet, M.M.
,
Antoniou, A.C.
,
McGuffog, L.
,
Humphreys, M.K.
,
Dunning, A.M.
,
Bojesen, S.E.
,
Nordestgaard, B.G.
Description :
Recently, a locus on chromosome 6q22.33 (rs2180341) was reported to be associated with increased breast cancer risk in the Ashkenazi Jewish (AJ) population, and this association was also observed in populations of non-AJ European ancestry. In the present study, we performed a large replication analy...
Repository :
Glasgow ePrints Service
Language(s) :
Undetermined
Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer
Author(s) :
Gaudet, M.M.
,
Kirchhoff, T.
,
Green, T.
,
Vijai, J.
,
Korn, J.M.
,
Guiducci, C.
,
Segre, A.V.
,
Mcgee, K.
,
McGuffog, L.
,
Kartsonaki, C.
Description :
Repository :
DSpace at Vrije Universiteit Amsterdam
Language(s) :
Undetermined
Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers
Author(s) :
Im, K.M.
,
Kirchhoff, T.
,
Wang, X.S.
,
Green, T.
,
Chow, C.Y.
,
Vijai, J.
,
Korn, J.
,
Gaudet, M.M.
,
Fredericksen, Z.
,
Pankratz, V.S.
Description :
Repository :
DSpace at Vrije Universiteit Amsterdam
Language(s) :
Undetermined
Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutatino carriers
Author(s) :
Antoniou, AC
,
Kuchenbaecker, KB
,
Soucy, P
,
Beesley, J
,
Chen, X
,
McGuffog, L
,
Lee, A
,
Barrowdale, D
,
Healey, S
,
Sinilnikova, OM
Description :
Repository :
The HKU Scholars Hub
Language(s) :
English
Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: Implications for risk prediction
Author(s) :
Antoniou, A.C.
,
Beesley, J.
,
McGuffog, L.
,
Sinilnikova, O.
,
Healey, S.
,
Neuhausen, S.L.
,
Ding, Y.C.
,
Rebbeck, T.R.
Description :
The known breast cancer susceptibility polymorphisms in FGFR2, TNRC9/TOX3, MAP3K1, LSP1, and 2q35 confer increased risks of breast cancer for BRCA1 or BRCA2 mutation carriers. We evaluated the associations of 3 additional single nucleotide polymorphisms (SNPs), rs4973768 in SLC4A7/NEK10, rs6504950 i...
Repository :
RePub (Erasmus University Repository)
Language(s) :
English
Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers
Author(s) :
Ramus, S.J.
,
kartsonaki, C.
,
Gayther, S.A.
,
Pharoah, P.D.P.
,
Sinilnikova, O.
,
Beesley, J.
,
Chenevix-Trench, G.
,
McGuffog, L.
Description :
Background Germline mutations in the BRCA1 and BRCA2 genes are associated with increased risks of breast and ovarian cancers. Although several common variants have been associated with breast cancer susceptibility in mutation carriers, none have been associated with ovarian cancer susceptibility. A ...
Repository :
RePub (Erasmus University Repository)
Language(s) :
English
Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers
Description :
Repository :
Oxford University Research Archive (ORA)
Language(s) :
Undetermined
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer
Author(s) :
Maxwell, C.A.
,
Benítez, J.
,
Gómez-Baldó, L.
,
Osorio, A.
,
Bonifaci, N.
,
Fernández-Ramires, R.
,
Costes, S.V.
,
Guinó, E.
Description :
Differentiated mammary epithelium shows apicobasal polarity, and loss of tissue organization is an early hallmark of breast carcinogenesis. In BRCA1 mutation carriers, accumulation of stem and progenitor cells in normal breast tissue and increased risk of developing tumors of basal-like type suggest...
Repository :
Publications of the Universiteit van Amsterdam
Language(s) :
Undetermined