Results
author = "Mazier, D."
Comparison of Immunoblotting, Calculation of the Goldmann-Witmer Coefficient, and Real-Time PCR Using Aqueous Humor Samples for Diagnosis of Ocular Toxoplasmosis▿ †
Description :
We compared three biological methods for the diagnosis of ocular toxoplasmosis (OT). Paired aqueous humor and serum samples from 34 patients with OT and from 76 patients with other ocular disorders were analyzed by three methods: immunoblotting or Western blotting (WB), the calculation of the Goldma...
Repository :
Europe PubMed Central
Language(s) :
English
Utility of Immunoblotting for Early Diagnosis of Toxoplasmosis Seroconversion in Pregnant Women▿
Author(s) :
Jost, C.
,
Touafek, F.
,
Fekkar, A.
,
Courtin, R.
,
Ribeiro, M.
,
Mazier, D.
,
Paris, L.
Description :
Congenital transmission of Toxoplasma gondii occurs mainly when a mother acquires the infection for the first time during pregnancy. It was recently shown that although early treatment of the primary infection during pregnancy has little or no impact on the fetomaternal transmission rate, it does re...
Repository :
Europe PubMed Central
Language(s) :
English
Hepatic phase of malaria: a crucial role as "go-between" with other stages.
Author(s) :
Mazier, D.
,
Goma, J.
,
Pied, S.
,
Renia, L.
,
Nussler, A.
,
Miltgen, F.
,
Mattei, D.
,
Grau, G.
Description :
Besides potential interest in itself, the hepatic stage of malaria might play a crucial role as "go-between" with other stages. When present in the parasitophorous vacuole, antibodies induced by both sporozoite and erythrocytic stages efficiently disturb hepatic development of the parasite. Likewise...
Repository :
Europe PubMed Central
Language(s) :
English
Fc-receptor-mediated intracellular delivery of Cu/Zn-superoxide dismutase (SOD1) protects against redox-induced apoptosis through a nitric oxide dependent mechanism.
Author(s) :
Vouldoukis, I.
,
Sivan, V.
,
Vozenin, M. C.
,
Kamaté, C.
,
Calenda, A.
,
Mazier, D.
,
Dugas, B.
Description :
BACKGROUND: Using specific antibodies against bovine Cu/Zn-superoxide dismutase (EC 1.15.1.1, SOD1) we demonstrated that anti-SOD antibodies (IgG1) are able to promote the intracellular translocation of the antioxidant enzyme. The transduction signalling mediated by IgG1 immune complexes are known t...
Repository :
Europe PubMed Central
Language(s) :
English
In vitro activities of two antimitotic compounds, pancratistatin and 7-deoxynarciclasine, against Encephalitozoon intestinalis, a microsporidium causing infections in humans.
Author(s) :
Ouarzane-Amara, M.
,
Franetich, J. F.
,
Mazier, D.
,
Pettit, G. R.
,
Meijer, L.
,
Doerig, C.
,
Desportes-Livage, I.
Description :
The antiparasitic effect of a collection of compounds with antimitotic activity has been tested on a mammalian cell line infected with Encephalitozoon intestinalis, a microsporidian causing intestinal and systemic infection in immunocompromised patients. The antiparasitic effect was evaluated by cou...
Repository :
Infoscience
Language(s) :
English
Non specific resistance against malaria pre-erythrocytic stages: involvement of acute phase proteins.
Description :
Levels of different acute phase proteins were compared in sera from parasitaemic and non-parasitaemic women living in a Plasmodium falciparum endemic area of Thailand. The ability of their sera to interfere with hepatic stage development of the parasite was examined. Correlations were found between ...
Repository :
Oxford University Research Archive (ORA)
Language(s) :
English
Enhanced epitopic response to a synthetic human malarial peptide by preimmunization with tetanus toxoid carrier.
Description :
Successful human vaccination by synthetic malarial sporozoite peptides may depend on the choice of an appropriate carrier. Tetanus toxoid (TT) has been proposed because of its safe and widespread use in humans. Paradoxically, however, prior exposure to this toxoid vaccine could produce specific epit...
Repository :
Europe PubMed Central
Language(s) :
English
Levels of antibodies to Plasmodium falciparum sporozoite surface antigens reflect malaria transmission rates and are persistent in the absence of reinfection.
Description :
Antibodies reacting with Plasmodium falciparum sporozoite surface antigens were measured by an immunofluorescence assay using wet preparations of sporozoites attached to poly-L-lysine-treated glass slides, a procedure which was found to be more specific than one using glutaraldehyde-treated and drie...
Repository :
Europe PubMed Central
Language(s) :
English
C-reactive protein protects against preerythrocytic stages of malaria.
Description :
We previously reported that low doses of interleukin-1 strongly inhibited in vitro development of the hepatic stages of Plasmodium falciparum and P. yoelii. Among several hypotheses, we considered the role of C-reactive protein (CRP), a major acute-phase reactant whose concentration increases marked...
Repository :
Europe PubMed Central
Language(s) :
English
Immunization with a recombinant C-terminal fragment of Plasmodium yoelii merozoite surface protein 1 protects mice against homologous but not heterologous P. yoelii sporozoite challenge.
Description :
It has been reported previously that immunization with recombinant protein containing the two epidermal growth factor (EGF)-like modules from merozoite surface protein 1 (MSP-1) of Plasmodium yoelii (strain YM) protects mice against a lethal blood-stage challenge with the same parasite strain. Since...
Repository :
Europe PubMed Central
Language(s) :
English