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author = "Matsuda, M"
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Found 118 documents, displaying page 1 of 12

Inhibitory effect of novobiocin on ribonucleic acid synthesis during germination of Bacillus subtilis spores.

Author(s) : Matsuda, M , Kameyama, T
Description : Novobiocin inhibited ribonculeic acid synthesis during germination of Bacillus subtilis spores. Transcription of certain kinds of genes probably required a preceding conformational change in deoxyribonucleic acid.
Repository : Europe PubMed Central
Language(s) : English

Isolation and purification of two antigenically active, "complimentary" polypeptide fragments of tetanus neurotoxin.

Author(s) : Matsuda, M , Yoneda, M
Description : Tetanus neurotoxin (molecular weight approximately 160,000) was purified from bacterial extracts (intracellular toxin) and mildly trypsinized and from culture filtrates (extracellular toxin). Both purified preparations could be dissociated reversibly into two polypeptide chains, with molecular weigh...
Repository : Europe PubMed Central
Language(s) : English

Biological and biochemical activity of v-Crk chimeras containing the SH2/SH3 regions of phosphatidylinositol-specific phospholipase C-gamma and Src.

Author(s) : Matsuda, M , Reichman, C T , Hanafusa, H
Description : The chicken CT10 virus oncogene product, P47gag-crk, contains SH2/SH3 domains that have been identified as conserved domains among proteins involved in signal transduction. We studied the functional similarity of the SH2/SH3 domains by replacing those of v-Crk with those of phosphatidylinositol-spec...
Repository : Europe PubMed Central
Language(s) : English

A glycoprotein in the plasma membrane matrix as a major potential substrate of p60v-src.

Author(s) : Hamaguchi, M , Matsuda, M , Hanafusa, H
Description : A potential substrate of p60v-src in Rous sarcoma virus-transformed cells was found to be a 130-kilodalton (kDa) glycoprotein which binds to lectin-Sepharose and can be immunoprecipitated by an anti-phosphotyrosine antibody. This glycoprotein was shown to be distinct from the fibronectin receptor an...
Repository : Europe PubMed Central
Language(s) : English

Identification of domains of the v-crk oncogene product sufficient for association with phosphotyrosine-containing proteins.

Author(s) : Matsuda, M , Mayer, B J , Hanafusa, H
Description : The oncogene product of the avian sarcoma virus CT10, P47gag-crk, contains the SH2, SH2', and SH3 domains and binds proteins in a phosphotyrosine (ptyr)-dependent manner. In this study, we have determined the region of P47gag-crk essential for binding to ptyr-containing proteins. Mutant P47gag-crk p...
Repository : Europe PubMed Central
Language(s) : English

Rapid, simplified method for production and purification of tetanus toxin.

Author(s) : Ozutsumi, K , Sugimoto, N , Matsuda, M
Description : A rapid, simplified method for production and purification of tetanus toxin from bacterial extracts was described. The extracts were prepared by stirring young cells (ca. 45-h culture) of Clostridium tetani in 1 M NaCl-0.1 M sodium citrate, pH 7.5, overnight at 0 to 4 degrees C. The toxin was purifi...
Repository : Europe PubMed Central
Language(s) : English

Inhibitory effect of cephalosporins on gamma-aminobutyric acid receptor binding in rat synaptic membranes.

Author(s) : Hori, S , Kurioka, S , Matsuda, M , Shimada, J
Description : Cephalosporins inhibited gamma-aminobutyric acid receptor binding in a concentration-dependent manner in vitro. Scatchard analysis revealed that cefazolin decreased the binding capacity but did not change the affinity of the receptor. It is suggested that this inhibition of gamma-aminobutyric acid r...
Repository : Europe PubMed Central
Language(s) : English

CrkII signals from epidermal growth factor receptor to Ras.

Author(s) : Kizaka-Kondoh, S , Matsuda, M , Okayama, H
Description : A rat fibroblast mutant defective in oncogenic transformation and signaling from epidermal growth factor receptor to Ras has been isolated. The mutant contains dominant negative-type point mutations in the C-terminal SH3 domain of one crkII gene. Among the adapters tested, the mutant is complemented...
Repository : Europe PubMed Central
Language(s) : English

Stimulation of DNA synthesis in osteoblast-like MC3T3-E1 cells by Bordetella bronchiseptica dermonecrotic toxin.

Author(s) : Horiguchi, Y , Sugimoto, N , Matsuda, M
Description : We investigated the effects of Bordetella bronchiseptica dermonecrotic toxin on DNA synthesis in MC3T3-E1 cells. The rate of [methyl-3H]thymidine incorporation increased in the toxin-treated cells more than 24 h after addition of the toxin under the serum-starved conditions. This effect was dependen...
Repository : Europe PubMed Central
Language(s) : English

Cerebral aneurysms associated with Behçet's disease: a case report

Author(s) : Nakasu, S , Kaneko, M , Matsuda, M
Description : Cerebral aneurysms in Behçet's disease are very rare. The role of vasculitis in the aetiology of these aneurysms has not been clarified. A 57 year old man with Behçet's disease is described, who had a subarachnoid hemorrhage due to rupture of a peripheral middle cerebral artery aneurysm. He underwen...
Repository : Europe PubMed Central
Language(s) : English
1 2 3 4 5 > >>

Found 118 documents, displaying page 1 of 12