Results
author = "Martial, Joseph"
Sprouty1, a new target of the angiostatic agent 16K prolactin, negatively regulates angiogenesis
Author(s) :
Sabatel, Céline
,
Cornet, Anne
,
Tabruyn, Sébastien
,
Malvaux, Ludovic
,
Castermans, Karolien
,
Martial, Joseph
,
Struman, Ingrid
Description :
BACKGROUND:Disorganized angiogenesis is associated with several pathologies, including cancer. The identification of new genes that control tumor neovascularization can provide novel insights for future anti-cancer therapies. Sprouty1 (SPRY1), an inhibitor of the MAPK pathway, might be one of these ...
Repository :
ORBi (University of Liège)
Language(s) :
English
Nanocoatings of inorganic surfaces by molecular biomimetic
Author(s) :
Vreuls, Christelle
,
Genin, Alexis
,
Zocchi, Germaine
,
Garitte, Geoffrey
,
Archambeau, Catherine
,
Van de Weerdt, Cécile
Description :
Repository :
ORBi (University of Liège)
Language(s) :
English
Genetically engineered polypeptides as a new tool for inorganic nano-particles separation in water based media
Author(s) :
Vreuls, Christelle
,
Genin, Alexis
,
Zocchi, Germaine
,
Boschini, Frédéric
,
Cloots, Rudi
,
Gilbert, Bernard
,
Martial, Joseph
Description :
The present paper relates a method for the separation of an insoluble inorganic powder out of a mixture of several insoluble powders with different chemical compositions, using genetically engineered inorganic binding peptides (GEPI). GEPI are small peptides that recognize and specifically bind an i...
Repository :
ORBi (University of Liège)
Language(s) :
English
Sprouty1, a new target of the angiostatic agent 16K prolactin, negatively regulates angiogenesis
Author(s) :
Sabatel, Céline
,
Cornet, Anne M
,
Tabruyn, Sébastien P
,
Malvaux, Ludovic
,
Castermans, Karolien
,
Martial, Joseph A
Description :
Repository :
Europe PubMed Central
Language(s) :
English
The Ornithine Decarboxylase Gene Is Essential for Cell Survival during Early Murine Development
Author(s) :
Pendeville, Hélène
,
Carpino, Nick
,
Marine, Jean-Christophe
,
Takahashi, Yutaka
,
Muller, Marc
,
Martial, Joseph A.
Description :
Overexpression and inhibitor studies have suggested that the c-Myc target gene for ornithine decarboxylase (ODC), the enzyme which converts ornithine to putrescine, plays an important role in diverse biological processes, including cell growth, differentiation, transformation, and apoptosis. To expl...
Repository :
Europe PubMed Central
Language(s) :
English
RUNX3, EGR1 and SOX9B Form a Regulatory Cascade Required to Modulate BMP-Signaling during Cranial Cartilage Development in Zebrafish
Author(s) :
Dalcq, Julia
,
Pasque, Vincent
,
Ghaye, Aurélie
,
Larbuisson, Arnaud
,
Motte, Patrick
,
Martial, Joseph A.
,
Muller, Marc
Description :
The cartilaginous elements forming the pharyngeal arches of the zebrafish derive from cranial neural crest cells. Their proper differentiation and patterning are regulated by reciprocal interactions between neural crest cells and surrounding endodermal, ectodermal and mesodermal tissues. In this stu...
Repository :
Europe PubMed Central
Language(s) :
English
The Antiangiogenic 16K Prolactin Impairs Functional Tumor Neovascularization by Inhibiting Vessel Maturation
Author(s) :
Nguyen, Ngoc-Quynh-Nhu
,
Castermans, Karolien
,
Berndt, Sarah
,
Herkenne, Stéphanie
,
Tabruyn, Sébastien
,
Blacher, Silvia
Description :
Background: Angiogenesis, the formation of new blood vessels from existing vasculature, plays an essential role in tumor growth, invasion, and metastasis. 16K hPRL, the antiangiogenic 16-kDa N-terminal fragment of human prolactin was shown to prevent tumor growth and metastasis by modifying tumor ve...
Repository :
ORBi (University of Liège)
Language(s) :
English
Stratégie verte et bio‐inspirée dans l’optique du développement de surfaces d’acier inoxydable antibactériennes durables
Author(s) :
Faure, Emilie
,
Lecomte, Philippe
,
Vreuls, Christelle
,
Van de Weerdt, Cécile
,
Archambeau, Catherine
,
Martial, Joseph
Description :
Repository :
ORBi (University of Liège)
Language(s) :
French
Inhibition of tumor growth and metastasis establishment by adenovirus-mediated gene transfer delivery of the antiangiogenic factor 16K hPRL
Author(s) :
Nguyen, Ngoc-Quynh-Nhu
,
Cornet, Anne
,
Blacher, Silvia
,
Tabruyn, Sébastien
,
Foidart, Jean-Michel
,
Noël, Agnès
,
Martial, Joseph
Description :
Tumor metastases, the most fearsome aspect of cancer, are generally resistant to conventional therapies. Angiogenesis is a crucial aspect of tumor growth and metastatic dissemination. Antiangiogenic therapy, therefore, holds potential as an attractive strategy for inhibiting metastasis development. ...
Repository :
ORBi (University of Liège)
Language(s) :
English
The antiangiogenic factor 16K human prolactin induces caspase-dependent apoptosis by a mechanism that requires activation of nuclear factor-kappa B
Author(s) :
Tabruyn, Sébastien
,
Sorlet, C. M.
,
Rentier-Delrue, Françoise
,
Bours, Vincent
,
Weiner, R. I.
,
Martial, Joseph
,
Struman, Ingrid
Description :
We have previously shown that the 16-kDa N-terminal fragment of human prolactin (16K hPRL) has antiangiogenic properties, including the ability to induce apoptosis in vascular endothelial cells. Here, we examined whether the nuclear factor-kappaB (NF-kappaB) signaling pathway was involved in mediati...
Repository :
ORBi (University of Liège)
Language(s) :
English