Results
author = "Malgrange, B."
1
Found 9 documents, displaying page 3 of 1
New insights in auditory organ development: the inner pillar cell goes it own way
Description :
Repository :
ORBi (University of Liège)
Language(s) :
English
Sox10 is not necessary for auditory neurons survival
Description :
Repository :
ORBi (University of Liège)
Language(s) :
English
Untangling the functional potential of PSA-NCAM-expressing cells in CNS development and brain repair strategies
Description :
Central nervous system (CNS) neural stem cells (NSCs), which are mostly defined by their ability to self-renew and to generate the three main cell lineages of the CNS, were isolated from discrete regions of the adult mammalian CNS including the subventricular zone (SVZ) of the lateral ventricle and ...
Repository :
Document Server@UHasselt
Language(s) :
English
Striatal PSA-NCAM(+) precursor cells from the newborn rat express functional glycine receptors
Author(s) :
Nguyen, L
,
Malgrange, B
,
Breuskin, I
,
Lallemend, F
,
Hans, G
,
Moonen, G
,
Belachew, S
,
RIGO, Jean-Michel
Description :
Immunocytochemical analysis showed that ionotropic glycine receptors are expressed in neurogenic progenitors purified from the newborn rat striatum and expressing the polysialylated form of the neural cell adhesion molecule, both in vitro and in situ. To ascertain whether glycine receptors were func...
Repository :
Document Server@UHasselt
Language(s) :
English
Substance P protects spiral ganglion neurons from apoptosis via PKC-Ca2+-MAPK/ERK pathways
Author(s) :
Lallemend, F
,
Lefebvre, PP
,
Hans, G
,
RIGO, Jean-Michel
,
Van De Water, TR
,
Moonen, G
,
Malgrange, B
Description :
In the current study, we have investigated the ability of substance P (SP) to protect 3-day-old (P3) rat spiral ganglion neurons (SGNs) from trophic factor deprivation (TFD)-induced cell death. The presence of SP high affinity neurokinin-1 receptor (NK1) transcripts was detected in the spiral gangli...
Repository :
Document Server@UHasselt
Language(s) :
English
Chemical inhibitors of cyclin-dependent kinases control proliferation, apoptosis and differentiation of oligodendroglial cells
Author(s) :
Nguyen, L
,
Malgrange, B
,
Rocher, V
,
Hans, G
,
Moonen, G
,
RIGO, Jean-Michel
,
Belachew, S.
Description :
Since cyclin-dependent kinases (Cdks) and their endogenous inhibitors (Cdkis) play an essential role as regulators of cell cycle withdrawal and onset of differentiation within oligodendroglial cells, we assessed here the effects of exogenous chemical Cdk inhibitors (CKIs) on cultured rat cortical ol...
Repository :
Document Server@UHasselt
Language(s) :
English
Autocrine/paracrine activation of the GABA(A) receptor inhibits the proliferation of neurogenic polysialylated neural cell adhesion molecule-positive (PSA-NCAM(+)) precursor cells from postnatal striatum
Author(s) :
Nguyen, L
,
Malgrange, B
,
Breuskin, I
,
Bettendorff, L
,
Moonen, G
,
Belachew, S
,
RIGO, Jean-Michel
Description :
GABA and its type A receptor (GABA(A)R) are present in the immature CNS and may function as growth-regulatory signals during the development of embryonic neural precursor cells. In the present study, on the basis of their isopycnic properties in a buoyant density gradient, we developed an isolation ...
Repository :
Document Server@UHasselt
Language(s) :
English
Peripheral benzodiazepine receptor (PBR) ligand cytotoxicity unrelated to PBR expression
Author(s) :
Hans, G.
,
Wislet-Gendebien, S.
,
Lallemend, F.
,
Robe, P.
,
Rogister, B.
,
Belachew, S.
,
Nguyen, L.
,
Malgrange, B.
,
Moonen, G.
Description :
Some synthetic ligands of the peripheral-type benzodiazepine receptor (PBR), an 18 kDa protein of the outer mitochondrial membrane, are cytotoxic for several tumor cell lines and arise as promising chemotherapeutic candidates. However, conflicting results were reported regarding the actual effect of...
Repository :
Document Server@UHasselt
Language(s) :
English
Beta-carbolines induce apoptosis in cultured cerebellar cyranule neurons via the mitochondrial pathway
Author(s) :
Hans, G.
,
Malgrange, B.
,
Lallemend, F.
,
Crommen, J.
,
Wislet-Gendebien, S.
,
Belachew, S.
,
RIGO, Jean-Michel
,
Robe, P.
Description :
N-Butyl-beta-carboline-3-carboxylate (betaCCB) is, together with 2-methyl-norharmanium and 2,9-dimethylnorharmanium ions, an endogenously occurring beta-carboline. Due to their structural similarities with the synthetic neurotoxin 1-methy14-phenyl-1,2,3,6-tetrahydropyridine (MPTP), harman and norhar...
Repository :
Document Server@UHasselt
Language(s) :
English
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Found 9 documents, displaying page 3 of 1