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author = "Lipsitch, Marc"
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Found 117 documents, displaying page 1 of 12

Vaccination against colonizing bacteria with multiple serotypes

Author(s) : Lipsitch, Marc
Description : Conjugate vaccines protect vaccinated individuals against both disease from and nasopharyngeal carriage of Streptococcus pneumoniae and Haemophilus influenzae. Protection is specific to the capsular serotype(s) included in the vaccine. This specificity has raised concern that vaccination against par...
Repository : Europe PubMed Central
Language(s) : English

Historical intensity of natural selection for resistance to tuberculosis.

Author(s) : Lipsitch, Marc , Sousa, Alexandra O
Description : Infections have long been thought to exert natural selection on humans. Infectious disease resistance is frequently invoked as a mechanism shaping human genetic diversity, but such hypotheses have rarely been quantitatively evaluated with direct measures of disease-related mortality. Enhancement of ...
Repository : Europe PubMed Central
Language(s) : English

Influenza seasonality: Lifting the fog

Author(s) : Lipsitch, Marc , Viboud, Cécile
Description :
Repository : Europe PubMed Central
Language(s) : English

Antiviral usage for H1N1 treatment: pros, cons and an argument for broader prescribing guidelines in the United States

Author(s) : Goldstein, Edward , Lipsitch, Marc
Description : Current CDC guidelines for antiviral treatment of people with influenza like illness (ILI) effectively discourage treatment of people with no underlying medical conditions unless they exhibit severe symptoms, such as evidence of lower respiratory tract infection or clinical deterioration. This guida...
Repository : Europe PubMed Central
Language(s) : English

H1N1 vaccination and adults with underlying health conditions in the US

Author(s) : Goldstein, Edward , Lipsitch, Marc
Description : 65% of fatalities from pH1N1 infections in a large US case series occur in adults with underlying health conditions other than pregnancy, but it appears that only relatively few high-risk adults will get vaccinated during the fall wave of pH1N1 transmission. There are several reasons for this probl...
Repository : Europe PubMed Central
Language(s) : English

The El Niño–Southern Oscillation (ENSO)–pandemic Influenza connection: Coincident or causal?

Author(s) : Shaman, Jeffrey , Lipsitch, Marc
Description : We find that the four most recent human influenza pandemics (1918, 1957, 1968, and 2009), all of which were first identified in boreal spring or summer, were preceded by La Niña conditions in the equatorial Pacific. Changes in the phase of the El Niño–Southern Oscillation have been shown to alter th...
Repository : Europe PubMed Central
Language(s) : English

Effect of human leukocyte antigen heterozygosity on infectious disease outcome: The need for allele-specific measures

Author(s) : Lipsitch Marc , Bergstrom Carl T , Antia Rustom
Description :

Abstract

Background

Doherty and Zinkernagel, who discovered that antigen presentation is restricted by the major histocompatibility complex (MHC, called HLA in humans), hypothesized that individuals heterozygous at particular MHC loci might be more resistant to particular infectious...

Repository : DOAJ-Articles
Language(s) : English

Effect of Human Leukocyte Antigen Heterozygosity on Infectious Disease Outcome: The Need for Allele-Specific Measures

Author(s) : Bergstrom, Carl T , Antia, Rustom , Lipsitch, Marc
Description : Background: Doherty and Zinkernagel, who discovered that antigen presentation is restricted by the major histocompatibility complex (MHC, called HLA in humans), hypothesized that individuals heterozygous at particular MHC loci might be more resistant to particular infectious diseases than the corres...
Repository : Digital Access to Scholarship at Harvard
Language(s) : English

Antimicrobial Use and Antimicrobial Resistance: A Population Perspective

Author(s) : Samore, Matthew H. , Lipsitch, Marc
Description : The need to stem the growing problem of antimicrobial resistance has prompted multiple, sometimes conflicting, calls for changes in the use of antimicrobial agents. One source of disagreement concerns the major mechanisms by which antibiotics select resistant strains. For infections like tuberculosi...
Repository : Digital Access to Scholarship at Harvard
Language(s) : English

Effect of human leukocyte antigen heterozygosity on infectious disease outcome: The need for allele-specific measures

Author(s) : Lipsitch, Marc , Bergstrom, Carl T , Antia, Rustom
Description :
Repository : Europe PubMed Central
Language(s) : English
1 2 3 4 5 > >>

Found 117 documents, displaying page 1 of 12