flag flag  

author = "Li, Fang"

Found 263 documents, displaying page 17 of 27

RNA-binding protein HuR regulates RGS4 mRNA stability in rabbit colonic smooth muscle cells

Description : Regulator of G protein signaling 4 (RGS4) regulates the strength and duration of G protein signaling and plays an important role in smooth muscle contraction, cardiac development, and psychiatric disorders. Little is known about the posttranscriptional regulation of RGS4 expression. We cloned the fu...
Repository : Europe PubMed Central
Language(s) : English

Brief Daily Periods of Unrestricted Vision Preserve Stereopsis in Strabismus

Description : In this study, stereopsis was preserved in optically strabismic infant monkeys by brief daily periods of normal binocular vision. This result indicates that the temporal integration properties of mechanisms responsible for vision development ensure that binocular vision development proceeds normally...
Repository : Europe PubMed Central
Language(s) : English

Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor

Description : Coronaviruses have evolved diverse mechanisms to recognize different receptors for their cross-species transmission and host-range expansion. Mouse hepatitis coronavirus (MHV) uses the N-terminal domain (NTD) of its spike protein as its receptor-binding domain. Here we present the crystal structure ...
Repository : Europe PubMed Central
Language(s) : English

PARP-14 Functions as a Transcriptional Switch for Stat6-dependent Gene Activation*

Description : A subset of poly ADP-ribose polymerases (PARP) that also contain macro domains regulate transcription. One such macro PARP, PARP-14 alters interleukin 4 (IL-4) and Stat6-dependent transcription. Stat6, activated by IL-4 plays an important role in T helper cell immunity and B cell responses. Here we ...
Repository : Europe PubMed Central
Language(s) : English

Chromatographic Fingerprint and the Simultaneous Determination of Five Bioactive Components of Geranium carolinianum L. Water Extract by High Performance Liquid Chromatography

Description : A simple and sensitive HPLC method has been developed in combination with fingerprint analysis and simultaneous determination of five markers, namely gallic acid, corilagin, methyl brevifolincarboxylate, ellagic acid and rutin for evaluation and quality control of Geranium carolinianum L. water extr...
Repository : Europe PubMed Central
Language(s) : English

Additive Contributions of Two Manganese-Cored Superoxide Dismutases (MnSODs) to Antioxidation, UV Tolerance and Virulence of Beauveria bassiana

Description : The biocontrol potential of entomopathogenic fungi against arthropod pests depends on not only their virulence to target pests but tolerance to outdoor high temperature and solar UV irradiation. Two Beauveria bassiana superoxide dismutases (SODs), BbSod2 and BbSod3, were characterized as cytosolic a...
Repository : Europe PubMed Central
Language(s) : English

Effect of Cocaine on Human Immunodeficiency Virus–Mediated Pulmonary Endothelial and Smooth Muscle Dysfunction

Description : Human immunodeficiency virus (HIV)–associated pulmonary arterial hypertension (PAH) is a devastating, noninfectious complication of acquired immune deficiency syndrome, and the majority of HIV-PAH cases occur in individuals with a history of intravenous drug use (IVDU). However, although HIV-1 and I...
Repository : Europe PubMed Central
Language(s) : English

Targeted Entry via Somatostatin Receptors Using a Novel Modified Retrovirus Glycoprotein That Delivers Genes at Levels Comparable to Those of Wild-Type Viral Glycoproteins

Description : Here we report a novel viral glycoprotein created by replacing a natural receptor-binding sequence of the ecotropic Moloney murine leukemia virus envelope glycoprotein with the peptide ligand somatostatin. This new chimeric glycoprotein, which has been named the Sst receptor binding site (Sst-RBS), ...
Repository : Europe PubMed Central
Language(s) : English

Found 263 documents, displaying page 17 of 27