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author = "Levine, M. M."
<< < 1 2 3 4 5 > >>

Found 97 documents, displaying page 2 of 10

Purification, morphology, and genetics of a new fimbrial putative colonization factor of enterotoxigenic Escherichia coli O159:H4.

Author(s) : Tacket, C O , Maneval, D R , Levine, M M
Description : The ability to colonize the small intestine is essential for the pathogenesis of diarrhea caused by enterotoxigenic Escherichia coli (ETEC). Colonization is mediated by fimbriae (pili), of which there are several antigenically distinct types, including colonization factor antigen I, colonization fac...
Repository : Europe PubMed Central
Language(s) : English

Protective immunity to Shiga-like toxin I following oral immunization with Shiga-like toxin I B-subunit-producing Vibrio cholerae CVD 103-HgR.

Author(s) : Acheson, D W , Levine, M M , Kaper, J B , Keusch, G T
Description : This study addresses a mechanism for inducing systemic immunity to Shiga-like toxins by oral administration of a Shiga-like toxin I B-subunit-expressing Vibrio cholerae vaccine strain [CVD 103-HgR(pDA60)]. Two sets of three rabbits were given either CVD 103-HgR or CVD 103-HgR(pDA60) orally. All rabb...
Repository : Europe PubMed Central
Language(s) : English

Improved GM1-enzyme-linked immunosorbent assay for detection of Escherichia coli heat-labile enterotoxin.

Author(s) : Ristaino, P A , Levine, M M , Young, C R
Description : Previously described GM1 ganglioside enzyme-linked immunosorbent assays (GM1-ELISA) for the detection of Escherichia coli heat-labile enterotoxin (LT) showed sensitivity equal to the Y-1 adrenal cell assay when anti-LT (a reagent not commercially available) was used. However, when antitoxin to immun...
Repository : Europe PubMed Central
Language(s) : English

Cholera.

Author(s) : Kaper, J B , Morris, J G , Levine, M M
Description : Despite more than a century of study, cholera still presents challenges and surprises to us. Throughout most of the 20th century, cholera was caused by Vibrio cholerae of the O1 serogroup and the disease was largely confined to Asia and Africa. However, the last decade of the 20th century has witnes...
Repository : Europe PubMed Central
Language(s) : English

Human immune response to Vibrio cholerae O1 whole cells and isolated outer membrane antigens.

Author(s) : Richardson, K , Kaper, J B , Levine, M M
Description : The serum immunoglobulin G (IgG) and mucosal secretory IgA (SIgA) response of human volunteers challenged with Vibrio cholerae O1 was analyzed for reactivity to V. cholerae O1 antigens by the immunoblot technique. Components of both in vitro- and in vivo (rabbit ligated ileal loop)-grown V. cholerae...
Repository : Europe PubMed Central
Language(s) : English

Enteroaggregative Escherichia coli elaborate a heat-stable enterotoxin demonstrable in an in vitro rabbit intestinal model.

Author(s) : Savarino, S J , Fasano, A , Robertson, D C , Levine, M M
Description : Enteroaggregative Escherichia coli (EAggEC) have been associated with persistent diarrhea in young children, but little is known about its pathogenesis. We assayed for enterotoxic activity in culture filtrates (CF) of EAggEC strains in Ussing chambers mounted with rabbit ileal mucosa. CF from strain...
Repository : Europe PubMed Central
Language(s) : English

New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development.

Author(s) : Levine, M M , Kaper, J B , Black, R E , Clements, M L
Description :
Repository : Europe PubMed Central
Language(s) : English

Adsorption and growth of Vibrio cholerae on chitin.

Author(s) : Nalin, D R , Daya, V , Reid, A , Levine, M M , Cisneros, L
Description : Incubation of Vibrio cholerae of O-group serotype 1 with chitin particles resulted in adsorption of vibrios onto chitin; chitin-adsorbed V. cholerae survived exposure to acid better than nonadsorbed vibrios. V. cholerae multiplied in dialyzed chitin suspended in 4.2% NaCl, suggesting that adherence ...
Repository : Europe PubMed Central
Language(s) : English

Pathogenesis of shigella diarrhea. Serum anticytotoxin antibody response produced by toxigenic and nontoxigenic Shigella dysenteriae 1.

Author(s) : Keusch, G T , Jacewicz, M , Levine, M M , Hornick, R B , Kochwa, S
Description : The serum antitoxin response to the cytotoxin contained in preparations of Shigella dysenteriae 1 (Shiga's bacillus) exotoxin was studied in natural and experimental infections of man. Natural infection resulted in the rapid appearance of toxin-neutralizing antibody, which disappeared some time betw...
Repository : Europe PubMed Central
Language(s) : English

Descriptive epidemiology of persistent diarrhoea among young children in rural northern India.

Author(s) : Bhan, M. K. , Bhandari, N. , Sazawal, S. , Clemens, J. , Raj, P. , Levine, M. M. , Kaper, J. B.
Description : In order to determine the descriptive epidemiology of persistent diarrhoea in rural northern India, a cohort of 963 children aged 0-71 months was followed prospectively for 12 months through weekly household visits. The incidence of persistent diarrhoea was 6.3 per 100 child-years among those aged 0...
Repository : Europe PubMed Central
Language(s) : English
<< < 1 2 3 4 5 > >>

Found 97 documents, displaying page 2 of 10