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author = "Lee, Yi-Ling"
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Found 2 documents, displaying page 1 of 1

Dengue Virus Targets the Adaptor Protein MITA to Subvert Host Innate Immunity

Author(s) : Yu, Chia-Yi , Chang, Tsung-Hsien , Liang, Jian-Jong , Chiang, Ruei-Lin , Lee, Yi-Ling , Liao, Ching-Len , Lin, Yi-Ling
Description : Dengue is one of the most important arboviral diseases caused by infection of four serotypes of dengue virus (DEN). We found that activation of interferon regulatory factor 3 (IRF3) triggered by viral infection and by foreign DNA and RNA stimulation was blocked by DEN-encoded NS2B3 through a proteas...
Repository : Europe PubMed Central
Language(s) : English

In Vivo Protection Provided by a Synthetic New Alpha-Galactosyl Ceramide Analog against Bacterial and Viral Infections in Murine Models▿

Author(s) : Lin, Kun-Hsien , Liang, Jian-Jong , Huang, Wen-I , Lin-Chu, Shao-Ying , Su, Ching-Yao , Lee, Yi-Ling , Jan, Jia-Tsong , Lin, Yi-Ling
Description : Alpha-galactosyl ceramide (α-GalCer) has been known to bind to the CD1d receptor on dendritic cells and activate invariant natural killer T (iNKT) cells, which subsequently secrete T-helper-cell 1 (Th1) and Th2 cytokines, which correlate with anti-infection activity and the prevention of autoimmune ...
Repository : Europe PubMed Central
Language(s) : English
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Found 2 documents, displaying page 1 of 1