Results
author = "Lebacq, Jean"
Effect of creatine supplementation on skeletal muscle of mdx mice.
Author(s) :
Louis, Magali
,
Raymackers, Jean Marc
,
Debaix, Huguette
,
Lebacq, Jean
,
Francaux, Marc
Description :
Dystrophic mice (mdx) and their controls (C57/Bl10) were fed for 1 month with a diet with or without creatine (Cr) enrichment. Cr supplementation reduced mass (by 19%, P < 0.01) and mean fiber surface (by 25%, P < 0.05) of fast-twitch mdx muscles. In both strains, tetanic tension increased slightly ...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
TRPC1: Subcellular Localization?
Author(s) :
Tajeddine, Nicolas
,
Zanou, Nadège
,
Van Schoor, Monique
,
Lebacq, Jean
,
Gailly, Philippe
Description :
Repository :
Europe PubMed Central
Language(s) :
English
An overview of monitoring and supplementation of omega 3 fatty acids in cystic fibrosis.
Author(s) :
Coste, Thierry
,
Armand, Martine
,
Lebacq, Jean
,
Lebecque, Patrick
,
Wallemacq, Pierre
,
Leal, Teresinha
Description :
Essential fatty acid deficiency has been increasingly reported in patients with cystic fibrosis. The purpose of this work is to critically summarize previous data on fatty acid status and omega3 supplementation in cystic fibrosis. Although the reported abnormalities differ from study to study, the t...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Calcium sensitivity of human single muscle fibers following plyometric training
Author(s) :
Malisoux, Laurent
,
Francaux, Marc
,
Nielens, Henri
,
Renard, Patricia
,
Lebacq, Jean
,
Theisen, Daniel
Description :
PURPOSE: To study the effect of plyometric training on Ca2+ sensitivity and the influence of troponin T (TnT) isoforms on Ca2+ -activation properties in skinned human muscle fibers. METHODS: Biopsies were obtained from the vastus lateralis of eight men before and after the training period. Chemicall...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Essential role of TRPV2 ion channel in the sensitivity of dystrophic muscle to eccentric contractions.
Author(s) :
Zanou, Nadège
,
Iwata, Yuko
,
Schakman, Olivier
,
Lebacq, Jean
,
Wakabayashi, Shigeo
,
Gailly, Philippe
Description :
Duchenne myopathy is a lethal disease due to the absence of dystrophin, a cytoskeletal protein. Muscles from dystrophin-deficient mice (mdx) typically present an exaggerated susceptibility to eccentric work characterized by an important force drop and an increased membrane permeability consecutive t...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
In vitro and in vivo chararcterization of the role of TRPC1 Channelin skeletal musclefunction
Author(s) :
Zanou, Nadège
,
Schakman, Olivier
,
Shapovalov, Georges
,
Gallo, Chiara
,
Dietrich, Alexander
,
Lebacq, Jean
,
Ruegg, Urs
Description :
Skeletal muscle contraction is reputed not to depend on extracellular Ca2+. Indeed, stricto sensu, excitation-contraction coupling does not necessitate entry of Ca2+. However, we previously observed that, during sustained activity (repeated contractions), entry of Ca2+ is needed to maintain force pr...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Azithromycin reduces spontaneous and induced inflammation in ΔF508 cystic fibrosis mice
Author(s) :
Legssyer Rachida
,
Huaux François
,
Lebacq Jean
,
Delos Monique
,
Marbaix Etienne
,
Lebecque Patrick
,
Lison Dominique
Description :
Abstract
Background
Inflammation plays a critical role in lung disease development and progression in cystic fibrosis. Azithromycin is used for the treatment of cystic fibrosis lung disease, although its mechanisms of action are poorly understood. We tested the hypothesis that azith...
Repository :
DOAJ-Articles
Language(s) :
English
Azithromycin reduces spontaneous and induced inflammation in DeltaF508 cystic fibrosis mice.
Author(s) :
Legssyer, Rachida
,
Huaux, François
,
Lebacq, Jean
,
Delos, Monique
,
Marbaix, Etienne
,
Lebecque, Patrick
,
Lison, Dominique
Description :
BACKGROUND: Inflammation plays a critical role in lung disease development and progression in cystic fibrosis. Azithromycin is used for the treatment of cystic fibrosis lung disease, although its mechanisms of action are poorly understood. We tested the hypothesis that azithromycin modulates lung in...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
In vivo chararcterization of the role of TRPC1 Channel in skeletal muscle function
Author(s) :
Schakman, Olivier
,
Zanou, Nadège
,
Shapovalov, Georges
,
Gallo, Chiara
,
Dietrich, Alexander
,
Lebacq, Jean
,
Ruegg, Urs
Description :
Skeletal muscle contraction is reputed not to depend on extracellular Ca2+. Indeed, stricto sensu, excitationcontraction coupling does not necessitate entry of Ca2+. However, we previously observed that, during sustained activity (repeated contractions), entry of Ca2+ is needed to maintain force pro...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Beneficial effects of creatine supplementation in dystrophic patients.
Author(s) :
Louis, Magali
,
Lebacq, Jean
,
Poortmans, Jacques R
,
Belpaire-Dethiou, Marie-Claude
,
Devogelaer, Jean-Pierre
,
Van Hecke, Paul
Description :
The effect of creatine (Cr) supplementation on muscle function and body composition of 12 boys with Duchenne muscular dystrophy and three with Becker dystrophy was evaluated by a randomized double-blind cross-over study (3 g Cr or maltodextrin daily for 3 months, with wash-out period of 2 months). A...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English