Results
author = "Kayser, Manfred"
Forensic pregnancy diagnostics with placental mRNA markers
Author(s) :
Gauvin, Jeanot
,
Zubakov, Dmitry
,
van Rhee-Binkhorst, Joke
,
Kloosterman, Ate
,
Steegers, Eric
,
Kayser, Manfred
Description :
Current methods for pregnancy diagnostics are based on immunodetection of pregnancy-specific proteins and in a forensic context suffer from sensitivity and specificity issues. Here, we applied reverse transcriptase polymerase chain reaction (RT-PCR) technology to 11 genes previously reported with pl...
Repository :
Europe PubMed Central
Language(s) :
English
Genome-wide Analysis Indicates More Asian than Melanesian Ancestry of Polynesians
Author(s) :
Kayser, Manfred
,
Lao, Oscar
,
Saar, Kathrin
,
Brauer, Silke
,
Wang, Xingyu
,
Nürnberg, Peter
,
Trent, Ronald J.
,
Stoneking, Mark
Description :
Analyses of mitochondrial DNA (mtDNA) and nonrecombining Y chromosome (NRY) variation in the same populations are sometimes concordant but sometimes discordant. Perhaps the most dramatic example known of the latter concerns Polynesians, in which about 94% of Polynesian mtDNAs are of East Asian origi...
Repository :
Europe PubMed Central
Language(s) :
English
Diurnal Rhythms in Blood Cell Populations and the Effect of Acute Sleep Deprivation in Healthy Young Men
Author(s) :
Ackermann, Katrin
,
Revell, Victoria L.
,
Lao, Oscar
,
Rombouts, Elwin J.
,
Skene, Debra J.
,
Kayser, Manfred
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Bona fide colour: DNA prediction of human eye and hair colour from ancient and contemporary skeletal remains
Author(s) :
Draus-Barini, Jolanta
,
Walsh, Susan
,
Pośpiech, Ewelina
,
Kupiec, Tomasz
,
Głąb, Henryk
,
Branicki, Wojciech
,
Kayser, Manfred
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Contrasting signals of positive selection in genes involved in human skin-color variation from tests based on SNP scans and resequencing
Author(s) :
de Gruijter Johanna
,
Lao Oscar
,
Vermeulen Mark
,
Xue Yali
,
Woodwark Cara
,
Gillson Christopher J
,
Coffey Alison J
,
Ayub Qasim
Description :
Abstract
Background
Numerous genome-wide scans conducted by genotyping previously ascertained single-nucleotide polymorphisms (SNPs) have provided candidate signatures for positive selection in various regions of the human genome, including in genes involved in pigmentation traits. ...
Repository :
DOAJ-Articles
Language(s) :
English
Contrasting signals of positive selection in genes involved in human skin color variation from tests based on SNP scans and resequencing
Author(s) :
de Gruijter, Johanna Maria
,
Lao, Oscar
,
Vermeulen, Mark
,
Xue, Yali
,
Woodwark, Cara
,
Gillson, Christopher J
,
Coffey, Alison J
Description :
Abstract Background Numerous genome-wide scans conducted by genotyping previously ascertained single-nucleotide polymorphisms (SNPs) have provided candidate signatures for positive selection in various regions of the human genome, including in genes involved in pigmentation traits. However, it is un...
Repository :
DSpace at Cambridge
Language(s) :
English
Y Chromosome STR Haplotypes and the Genetic Structure of U.S. Populations of African, European, and Hispanic Ancestry
Author(s) :
Kayser, Manfred
,
Brauer, Silke
,
Schädlich, Hiltrud
,
Prinz, Mechthild
,
Batzer, Mark A.
,
Zimmerman, Peter A.
,
Boatin, B. A.
Description :
To investigate geographic structure within U.S. ethnic populations, we analyzed 1705 haplotypes on the basis of 9 short tandem repeat (STR) loci on the Y-chromosome from 9–11 groups each of African-Americans, European-Americans, and Hispanics. There were no significant differences in the distributio...
Repository :
Europe PubMed Central
Language(s) :
English
An Extensive Analysis of Y-Chromosomal Microsatellite Haplotypes in Globally Dispersed Human Populations
Author(s) :
Kayser, Manfred
,
Krawczak, Michael
,
Excoffier, Laurent
,
Dieltjes, Patrick
,
Corach, Daniel
,
Pascali, Vincente
,
Gehrig, Christian
Description :
The genetic variance at seven Y-chromosomal microsatellite loci (or short tandem repeats [STRs]) was studied among 986 male individuals from 20 globally dispersed human populations. A total of 598 different haplotypes were observed, of which 437 (73.1%) were each found in a single male only. Populat...
Repository :
Europe PubMed Central
Language(s) :
English
A Worldwide Survey of Human Male Demographic History Based on Y-SNP and Y-STR Data from the HGDP–CEPH Populations
Author(s) :
Shi, Wentao
,
Ayub, Qasim
,
Vermeulen, Mark
,
Shao, Rong-guang
,
Zuniga, Sofia
,
van der Gaag, Kristiaan
,
de Knijff, Peter
Description :
We have investigated human male demographic history using 590 males from 51 populations in the Human Genome Diversity Project - Centre d’Étude du Polymorphisme Humain worldwide panel, typed with 37 Y-chromosomal Single Nucleotide Polymorphisms and 65 Y-chromosomal Short Tandem Repeats and analyzed w...
Repository :
Europe PubMed Central
Language(s) :
English
MicroRNA markers for forensic body fluid identification obtained from microarray screening and quantitative RT-PCR confirmation
Author(s) :
Zubakov, Dmitry
,
Boersma, Anton W. M.
,
Choi, Ying
,
van Kuijk, Patricia F.
,
Wiemer, Erik A. C.
,
Kayser, Manfred
Description :
MicroRNAs (miRNAs) are non-protein coding molecules with important regulatory functions; many have tissue-specific expression patterns. Their very small size in principle makes them less prone to degradation processes, unlike messenger RNAs (mRNAs), which were previously proposed as molecular tools ...
Repository :
Europe PubMed Central
Language(s) :
English