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author = "Izui, S."
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Found 4 documents, displaying page 1 of 1

Enriched lipid diet accelerates lupus nephritis in NZB x W mice. Synergistic action of immune complexes and lipid in glomerular injury.

Author(s) : Kelley, V. E. , Izui, S.
Description : The effect of a lipid-rich diet was investigated in autoimmune NZB x W mice with immune complex lupus nephritis. Mice on an enriched lipid diet died sooner than controls. This increase in dietary fat elevated serum cholesterol levels and was associated with an accelerated loss of renal function. Ult...
Repository : Europe PubMed Central
Language(s) : English

IgG3 cryoglobulins in autoimmune MRL-lpr/lpr mice: immunopathogenesis, therapeutic approaches and relevance to similar human diseases.

Description : MRL-lpr/lpr mice spontaneously develop an autoimmune disease resembling systemic lupus erythematosus and rheumatoid arthritis. One of the unique serological abnormalities in this strain is remarkably high concentrations of cryoglobulins. Analysis of immunoglobulin components in their cryoglobulins h...
Repository : Europe PubMed Central
Language(s) : English

Exacerbation of autoantibody-mediated hemolytic anemia by viral infection.

Description : Strong enhancement of the pathogenicity of an antierythrocyte monoclonal antibody was observed after infection of mice with lactate dehydrogenase-elevating virus. While injection of the antierythrocyte antibody alone induced only moderate anemia, concomitant infection with this virus, which is harml...
Repository : DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) : English

Tubular up-regulation of clusterin mRNA in murine lupus-like nephritis.

Description : Clusterin, a widely distributed glycoprotein, is detected in most tissues and in numerous physiological fluids. In the kidney, this protein is constitutively expressed in tubular epithelial cells, and its expression is enhanced following tubular injuries. In addition, clusterin has been detected in ...
Repository : Europe PubMed Central
Language(s) : English
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Found 4 documents, displaying page 1 of 1