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author = "Hernandez Pando, Rogelio"

Found 34 documents, displaying page 1 of 4

Modelling of Cerebral Tuberculosis: Hope for Continuous Research in Solving the Enigma of the Bottom Billion’s Disease

Description : Cerebral tuberculosis is a severe type of extrapulmonary disease that is highly predominant in children. It is thought that meningeal tuberculosis, the most common form of cerebral tuberculosis, begins with respiratory infection followed by early haematogenous dissemination to extrapulmonary sites i...
Repository : Europe PubMed Central
Language(s) : English

Peroxynitrite decomposition catalyst ameliorates renal damage and protein nitration in cisplatin-induced nephrotoxicity in rats

Description :

Abstract

Background

Oxidative stress is involved in cisplatin-nephrotoxicity. However, it has not completely established if reactive nitrogen species and nitrosative stress are involved in this experimental model. The purpose of this work was to study the role of peroxynitrite, a re...

Repository : DOAJ-Articles
Language(s) : English

Péptidos antimicrobianos en la inmunidad innata de enfermedades infecciosas

Description : Los péptidos antimicrobianos son moléculas efectoras clave en la inmunidad innata. Generalmente contienen de 15 a 45 residuos de aminoácidos y en su gran mayoría poseen carga positiva, además de que tienen la propiedad de ser anfipáticos. Estos péptidos son secretados por células epiteliales y leuco...
Repository : DOAJ-Articles
Language(s) : Undetermined

Down-regulation of transforming growth factor-β type II receptor (TGF-βRII) protein and mRNA expression in cervical cancer

Description :

Abstract

Background

Cervical carcinogenesis is a multistep process initiated by "high risk" human papillomaviruses (HR-HPV), most commonly HPV16. The infection per se is, however, not sufficient to induce malignant conversion. Transforming Growth Factor β (TGF-β) inhibits e...

Repository : DOAJ-Articles
Language(s) : English

Orally Administered Mycobacterium vaccae Modulates Expression of Immunoregulatory Molecules in BALB/c Mice with Pulmonary Tuberculosis ▿

Description : The environmental saprophyte Mycobacterium vaccae induces a Th1 response and cytotoxic T cells that recognize M. tuberculosis, and by subcutaneous injection, it is therapeutic for pulmonary tuberculosis (TB) induced by high-dose challenge in BALB/c mice. However, M. vaccae also drives regulatory T c...
Repository : Europe PubMed Central
Language(s) : English

The Importance of Animal Models in Tuberculosis Vaccine Development

Description : Research, development, and production of vaccines are still highly dependent on the use of animal models in the various evaluation steps. Despite this fact, there are strong interests and ongoing efforts to reduce the use of animals in vaccine development. Tuberculosis vaccine development is one imp...
Repository : Europe PubMed Central
Language(s) : English

Hypothyroidism attenuates protein tyrosine nitration, oxidative stress and renal damage induced by ischemia and reperfusion: effect unrelated to antioxidant enzymes activities

Description :

Abstract

Background

It has been established that hypothyroidism protects rats against renal ischemia and reperfusion (IR) oxidative damage. However, it is not clear if hypothyroidism is able to prevent protein tyrosine nitration, an index of nitrosative stress, induced by IR or if a...

Repository : DOAJ-Articles
Language(s) : English

Found 34 documents, displaying page 1 of 4