Results
author = "Gruters, R A"
Phenotypic heterogeneity in a panel of infectious molecular human immunodeficiency virus type 1 clones derived from a single individual.
Author(s) :
Groenink, M
,
Fouchier, R A
,
de Goede, R E
,
de Wolf, F
,
Gruters, R A
,
Cuypers, H T
,
Huisman, H G
,
Tersmette, M
Description :
Previously, we and others have demonstrated a relation between the clinical course of human immunodeficiency virus type 1 (HIV-1) infection and biological properties of HIV-1 variants such as replication rate, syncytium-inducing (SI) capacity, and cytotropism. For the molecular analysis of the biolo...
Repository :
Europe PubMed Central
Language(s) :
English
Functional and phenotypic evidence for a selective loss of memory T cells in asymptomatic human immunodeficiency virus-infected men.
Author(s) :
van Noesel, C J
,
Gruters, R A
,
Terpstra, F G
,
Schellekens, P T
,
van Lier, R A
,
Miedema, F
Description :
In addition to a well-documented depletion of CD4+ T helper cells in later stages of human immunodeficiency virus (HIV) infection, evidence has been provided for a specific unresponsiveness to triggering either by specific antigen in the context of autologous major histocompatibility molecules (self...
Repository :
Europe PubMed Central
Language(s) :
English
Siderophores and outer membrane proteins of antagonistic, plant-growth-stimulating, root-colonizing Pseudomonas spp.
Author(s) :
de Weger, L A
,
van Boxtel, R
,
van der Burg, B
,
Gruters, R A
,
Geels, F P
,
Schippers, B
,
Lugtenberg, B
Description :
As an approach to understanding the molecular basis of the reduction in plant yield depression by root-colonizing Pseudomonas spp. and especially of the role of the bacterial cell surfaces in this process, we characterized 30 plant-root-colonizing Pseudomonas spp. with respect to siderophore product...
Repository :
Europe PubMed Central
Language(s) :
English
HIV-2 infection in 12 European residents: virus characteristics and disease progression.
Description :
OBJECTIVE: To assess the disease progression rate among 12 HIV-2-infected West European residents (nine of West African descent), compared with the disease progression rate among HIV-1-infected individuals of the same population, and the characteristics of the HIV-2 strains involved. METHODS: HIV-2-...
Repository :
RePub (Erasmus University Repository)
Language(s) :
English
Construction and characterisation of infectious recombinant HIV-1 clones containing CTL epitopes from structural proteins in Nef.
Author(s) :
Guillon, C.
,
Boers, P.H.M.
,
Verschuren, E.J.
,
Gruters, R.A.
,
Osterhaus, A.D.M.E.
,
Baalen, C.A. van
Description :
In this study the construction is described of HIV-1 molecular clones in which CTL epitopes from RT or Env late proteins were inserted into the Nef early protein. The ectopic epitopes were efficiently processed from the recombinant Nef proteins, were recognized by their cognate CTL in cytolytic assa...
Repository :
RePub (Erasmus University Repository)
Language(s) :
English
SIVdrl detection in captive mandrills: are mandrills infected with a third strain of simian immunodeficiency virus?
Author(s) :
Kuyl, A.C. van der
,
Burg, R. van den
,
Hoyer, M.J.
,
Gruters, R.A.
,
Osterhaus, A.D.M.E.
,
Berkhout, B.
Description :
A pol-fragment of simian immunodeficiency virus (SIV) that is highly related to SIVdrl-pol from drill monkeys (Mandrillus leucophaeus) was detected in two mandrills (Mandrillus sphinx) from Amsterdam Zoo. These captivity-born mandrills had never been in contact with drill monkeys, and were unlikely ...
Repository :
RePub (Erasmus University Repository)
Language(s) :
English
Coreceptor usage of human immunodeficiency virus type 2 primary isolates and biological clones is broad and does not correlate with their syncytium-inducing capacities
Author(s) :
Guillon, C.
,
Boers, P.H.M.
,
Gruters, R.A.
,
Schutten, M.
,
Ende, M.E. van der
,
Osterhaus, A.D.M.E.
Description :
Entry of human immunodeficiency virus type 1 (HIV-1) into target cells is
mediated by binding of the surface envelope glycoprotein to the CD4
molecule. Interaction of the resulting CD4-glycoprotein complex with
alpha- or beta-chemokine receptors, depending on the biological phenoty...
Repository :
RePub (Erasmus University Repository)
Language(s) :
English
Kinetics of antiviral activity by human immunodeficiency virus type 1-specific cytotoxic T lymphocytes (CTL) and rapid selection of CTL escape virus in vitro
Author(s) :
Schutten, M.
,
Huisman, R.C.
,
Boers, P.H.M.
,
Gruters, R.A.
,
Baalen, C.A. van
,
Osterhaus, A.D.M.E.
Description :
The antiviral activity of a CD8(+) cytotoxic T-lymphocyte (CTL) clone
(TCC108) directed against a newly identified HLA-B14-restricted epitope,
human immunodeficiency virus type 1 (HIV-1) Rev(67-75) SAEPVPLQL, was
analyzed with respect to its kinetics of target cell lysis and inhibi...
Repository :
RePub (Erasmus University Repository)
Language(s) :
English
Antibody-mediated enhancement of human immunodeficiency virus type 1 infectivity is determined by the structure of gp120 and depends on modulation of the gp120-CCR5 interaction
Description :
In this study, we characterized the viral determinants of coreceptor usage in relation to susceptibility to antibody-mediated neutralization or enhancement of infectivity by using chimeras of three highly related human immunodeficiency virus type 1 (HIV-1) isolates of different phenotypes. We found ...
Repository :
RePub (Erasmus University Repository)
Language(s) :
English
SIVdrl detection in captive mandrills: are mandrills infected with a third strain of simian immunodeficiency virus?
Author(s) :
Kuyl, A.C. van der
,
Burg, R. van den
,
Hoyer, M.
,
Gruters, R.A.
,
Osterhaus, A.D.M.E.
,
Berkhout, B.
Description :
Repository :
Publications of the Universiteit van Amsterdam
Language(s) :
Undetermined