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author = "George, James W."
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Found 5 documents, displaying page 1 of 1

The tight linkage between DNA replication and double-strand break repair in bacteriophage T4

Description : Double-strand break (DSB) repair and DNA replication are tightly linked in the life cycle of bacteriophage T4. Indeed, the major mode of phage DNA replication depends on recombination proteins and can be stimulated by DSBs. DSB-stimulated DNA replication is dramatically demonstrated when T4 infects ...
Repository : Europe PubMed Central
Language(s) : English

Restoration of Nucleotide Excision Repair in a Helicase-Deficient XPD Mutant from Intragenic Suppression by a Trichothiodystrophy Mutation

Description : The UV-sensitive V-H1 cell line has a T46I substitution mutation in the Walker A box in both alleles of XPD and lacks DNA helicase activity. We characterized three partial revertants that curiously display intermediate UV cytotoxicity (2- to 2.5-fold) but normal levels of UV-induced hprt mutations. ...
Repository : Europe PubMed Central
Language(s) : English
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Found 5 documents, displaying page 1 of 1