Results
author = "Elofsson, Arne"
Evaluating dosage compensation as a cause of duplicate gene retention in Paramecium tetraurelia
Author(s) :
Hughes, Timothy
,
Ekman, Diana
,
Ardawatia, Himanshu
,
Elofsson, Arne
,
Liberles, David A
Description :
Can dosage compensation completely explain gene retention after whole-genome duplication?
Repository :
Europe PubMed Central
Language(s) :
English
A study of quality measures for protein threading models
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps
Description :
Background Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic trees and protein structure prediction. Numerous studies have shown that the incorporation of predicted secondary structure...
Repository :
DSpace@MIT - MIT's online institutional repository
Language(s) :
English
Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps
Description :
Abstract
Background
Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic trees and protein structure prediction. Numerous studies have shown that the incorporation of pre...
Repository :
DOAJ-Articles
Language(s) :
English
Quantitative assessment of the structural bias in protein-protein interaction assays.
Description :
With recent publications of several large-scale protein-protein interaction (PPI) studies, the realization of the full yeast interaction network is getting closer. Here, we have analysed several yeast protein interaction datasets to understand their strengths and weaknesses. In particular, we invest...
Repository :
Publikationer från Stockholms universitet
Language(s) :
English
Prediction of membrane-protein topology from first principles
Author(s) :
Bernsel, Andreas
,
Viklund, Håkan
,
Falk, Jenny
,
Lindahl, Erik
,
von Heijne, Gunnar
,
Elofsson, Arne
Description :
The current best membrane-protein topology-prediction methods are typically based on sequence statistics and contain hundreds of parameters that are optimized on known topologies of membrane proteins. However, because the insertion of transmembrane helices into the membrane is the outcome of molecul...
Repository :
Europe PubMed Central
Language(s) :
English
Repositioning of transmembrane alpha-helices during membrane protein folding
Author(s) :
Kauko, Anni
,
Hedin, Linnea E
,
Thebaud, Estelle
,
Cristobal, Susana
,
Elofsson, Arne
,
von Heijne, Gunnar
Description :
We have determined the optimal placement of individual transmembrane helices in the Pyrococcus horikoshii Glt(Ph) glutamate transporter homolog in the membrane. The results are in close agreement with theoretical predictions based on hydrophobicity, but do not, in general, match the known three-dime...
Repository :
Publikationer från Stockholms universitet
Language(s) :
English
Genomic evolution and complexity of the Anaphase-promoting Complex (APC) in land plants
Author(s) :
Lima Marcelo de F
,
Eloy Núbia B
,
Pegoraro Camila
,
Sagit Rauan
,
Rojas Cristian
,
Bretz Thiago
,
Vargas Lívia
,
Elofsson Arne
Description :
Abstract
Background
The orderly progression through mitosis is regulated by the Anaphase-Promoting Complex (APC), a large multiprotein E3 ubiquitin ligase that targets key cell-cycle regulators for destruction by the 26 S proteasome. The APC is composed of at least 11 sub...
Repository :
DOAJ-Articles
Language(s) :
English
Genomic evolution and complexity of the Anaphase-promoting Complex (APC) in land plants
Author(s) :
Lima, Marcelo de F
,
Eloy, Núbia B
,
Pegoraro, Camila
,
Sagit, Rauan
,
Rojas, Cristian
,
Bretz, Thiago
,
Vargas, Lívia
Description :
Repository :
Europe PubMed Central
Language(s) :
English
PONGO: a web server for multiple predictions of all-alpha transmembrane proteins
Author(s) :
Amico, Mauro
,
Finelli, Michele
,
Rossi, Ivan
,
Zauli, Andrea
,
Elofsson, Arne
,
Viklund, Håkan
,
von Heijne, Gunnar
,
Jones, David
Description :
The annotation efforts of the BIOSAPIENS European Network of Excellence have generated several distributed annotation systems (DAS) with the aim of integrating Bioinformatics resources and annotating metazoan genomes (). In this context, the PONGO DAS server () provides the annotation on predictive ...
Repository :
Europe PubMed Central
Language(s) :
English