flag flag  

Search all repositories
add criteria
Close advanced options Search for

 

Enter more search criteria
Publication Date
     
From
To
Document Language
Document Type
Repositories
New Search Save Search Refine Search
Results
author = "Elofsson, Arne"
<< < 1 2 3 4 5 > >>

Found 41 documents, displaying page 3 of 5

Estimating the length of transmembrane helices using Z-coordinate predictions

Author(s) : Papaloukas, Costas , Granseth, Erik , Viklund, Håkan , Elofsson, Arne
Description : Zpred2 is an improved version of ZPRED, a predictor for the Z-coordinates of α-helical membrane proteins, that is, the distance of the residues from the center of the membrane. Using principal component analysis and a set of neural networks, Zpred2 analyzes data extracted from the amino acid sequenc...
Repository : Europe PubMed Central
Language(s) : English

Using multiple templates to improve quality of homology models in automated homology modeling

Author(s) : Larsson, Per , Wallner, Björn , Lindahl, Erik , Elofsson, Arne
Description : When researchers build high-quality models of protein structure from sequence homology, it is today common to use several alternative target-template alignments. Several methods can, at least in theory, utilize information from multiple templates, and many examples of improved model quality have bee...
Repository : Europe PubMed Central
Language(s) : English

What properties characterize the hub proteins of the protein-protein interaction network of Saccharomyces cerevisiae?

Author(s) : Ekman, Diana , Light, Sara , Björklund, Åsa K , Elofsson, Arne
Description : An analysis of hubs (proteins with many interactors) and non-hubs in the S. cerevisiae protein interaction network shows that hub proteins are enriched with multiple and repeated domains.
Repository : Europe PubMed Central
Language(s) : English

Improved predictions by Pcons.net using multiple templates

Author(s) : Larsson, Per , Skwark, Marcin J. , Wallner, Björn , Elofsson, Arne
Description : Summary: Multiple templates can often be used to build more accurate homology models than models built from a single template. Here we introduce PconsM, an automated protocol that uses multiple templates to build protein models. PconsM has been among the top-performing methods in the recent CASP exp...
Repository : Europe PubMed Central
Language(s) : English

TOPCONS: consensus prediction of membrane protein topology

Author(s) : Bernsel, Andreas , Viklund, Håkan , Hennerdal, Aron , Elofsson, Arne
Description : TOPCONS (http://topcons.net/) is a web server for consensus prediction of membrane protein topology. The underlying algorithm combines an arbitrary number of topology predictions into one consensus prediction and quantifies the reliability of the prediction based on the level of agreement between th...
Repository : Europe PubMed Central
Language(s) : English

Internal duplications in α-helical membrane protein topologies are common but the nonduplicated forms are rare

Author(s) : Hennerdal, Aron , Falk, Jenny , Lindahl, Erik , Elofsson, Arne
Description : Many α-helical membrane proteins contain internal symmetries, indicating that they might have evolved through a gene duplication and fusion event. Here, we have characterized internal duplications among membrane proteins of known structure and in three complete genomes. We found that the majority of...
Repository : Europe PubMed Central
Language(s) : English

Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps

Author(s) : Ohlson, Tomas , Aggarwal, Varun , Elofsson, Arne , MacCallum, Robert M
Description :
Repository : Europe PubMed Central
Language(s) : English

Improved detection of homologous membrane proteins by inclusion of information from topology predictions

Author(s) : Hedman, Maria , Deloof, Hans , Von Heijne, Gunnar , Elofsson, Arne
Description : A total of 20%–25% of the proteins in a typical genome are helical membrane proteins. The transmembrane regions of these proteins have markedly different properties when compared with globular proteins. This presents a problem when homology search algorithms optimized for globular proteins are appli...
Repository : Europe PubMed Central
Language(s) : English

LiveBench-1: Continuous benchmarking of protein structure prediction servers

Author(s) : Bujnicki, Janusz M. , Elofsson, Arne , Fischer, Daniel , Rychlewski, Leszek
Description : We present a novel, continuous approach aimed at the large-scale assessment of the performance of available fold-recognition servers. Six popular servers were investigated: PDB-Blast, FFAS, T98-lib, GenTHREADER, 3D-PSSM, and INBGU. The assessment was conducted using as prediction targets a large num...
Repository : Europe PubMed Central
Language(s) : English

Pcons: A neural-network–based consensus predictor that improves fold recognition

Author(s) : Lundström, Jesper , Rychlewski, Leszek , Bujnicki, Janusz , Elofsson, Arne
Description : During recent years many protein fold recognition methods have been developed, based on different algorithms and using various kinds of information. To examine the performance of these methods several evaluation experiments have been conducted. These include blind tests in CASP/CAFASP, large scale b...
Repository : Europe PubMed Central
Language(s) : English
<< < 1 2 3 4 5 > >>

Found 41 documents, displaying page 3 of 5