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author = "Dey, Sudhansu K."

Found 37 documents, displaying page 4 of 4

Global gene expression analysis identifies molecular pathways distinguishing blastocyst dormancy and activation

Description : Delayed implantation (embryonic diapause) occurs when the embryo at the blastocyst stage achieves a state of suspended animation. During this period, blastocyst growth is very slow, with minimal or no cell division. Nearly 100 mammals in seven different orders undergo delayed implantation, but the u...
Repository : Europe PubMed Central
Language(s) : English

Heightened Expression of Cyclooxygenase-2 and Peroxisome Proliferator-Activated Receptor-δ in Human Endometrial Adenocarcinoma1

Description : Epidemiological studies indicate that nonsteroidal anti-inflammatory drugs (NSAIDs) significantly reduce the risk and mortality from colorectal cancer, in part by inhibiting prostaglandin (PG) synthesis. Cyclooxygenase (COX), the rate-limiting enzyme in PG biosynthesis, exists in two isoforms, COX-1...
Repository : Europe PubMed Central
Language(s) : English

Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARδ

Description : We have demonstrated previously that cyclo-oxygenase-2 (COX2), the rate-limiting enzyme in the biosynthesis of prostaglandins (PGs), is essential for blastocyst implantation and decidualization. However, the candidate PG(s) that participates in these processes and the mechanism of its action remain ...
Repository : Europe PubMed Central
Language(s) : English

Spatial and temporal alterations of phospholipids determined by mass spectrometry during mouse embryo implantation[S]

Description : Molecular events involved in successful embryo implantation are not well understood. In this study, we used MALDI imaging mass spectrometry (IMS) technologies to characterize the spatial and temporal distribution of phospholipid species associated with mouse embryo implantation. Molecular images sho...
Repository : Europe PubMed Central
Language(s) : English

Two Pathways for Cyclooxygenase-2 Protein Degradation in Vivo*

Description : COX-2, formally known as prostaglandin endoperoxide H synthase-2 (PGHS-2), catalyzes the committed step in prostaglandin biosynthesis. COX-2 is induced during inflammation and is overexpressed in colon cancer. In vitro, an 18-amino acid segment, residues 595–612, immediately upstream of the C-termin...
Repository : Europe PubMed Central
Language(s) : English

Uterine FK506-binding protein 52 (FKBP52)–peroxiredoxin-6 (PRDX6) signaling protects pregnancy from overt oxidative stress

Description : Immunophilin FK506-binding protein 52 (FKBP52) is a cochaperone that binds to the progesterone receptor (PR) to optimize progesterone (P4)-PR signaling. We recently showed that Fkbp52-deficient (Fkbp52−/−) mice have reduced uterine PR responsiveness and implantation failure which is rescued by exces...
Repository : Europe PubMed Central
Language(s) : English

Found 37 documents, displaying page 4 of 4