Results
author = "De Witte, Philippe"
Ethanol-conditioned withdrawal syndrome
Description :
The withdrawal syndrome is closely related to the concepts of tolerance and physical dependence. The chronic consumption of a drug is believed to induce adaptive changes that are designed to oppose the acute effects of the drug. Such adaptive changes increase the tolerance to acute drug effects but ...
Repository :
ORBi (University of Liège)
Language(s) :
English
Effets comportementaux et neurochimiques de stimuli associés à l’administration d'éthanol: implications pour les comportements d'alcoolisation Behavioral and neurochemical effects of ethanol-conditioned stimuli: implications in alcohol consumption
Description :
Les drogues, y compris l’alcool, peuvent servir de stimuli inconditionnels dans des situations d’apprentissage par conditionnement. Les stimuli environnementaux qui accompagnent systématiquement l’administration d’alcool peuvent ainsi acquérir le statut de stimuli conditionnés capables d’induire à e...
Repository :
ORBi (University of Liège)
Language(s) :
French
Ethanol induces higher BEC in CB1 cannabinoid receptor knockout mice while decreasing ethanol preference.
Description :
AIMS: Previous studies have shown that CB(1) cannabinoid receptors are involved in the behavioural effects induced by chronic ethanol administration in Wistar rats by using SR 141716, a CB(1) cannabinoid receptor antagonist. These studies have now been extended to investigate the effect of acute and...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
L-NNA decreases cortical vascularization, alcohol preference and withdrawal in alcoholic rats.
Description :
Rats, which were made chronically alcoholic in combination with L-N(o)-nitro-arginine (L-NNA) treatment (5 mg/kg/day), a nitric oxide (NO) synthase inhibitor, showed a significant decrease in their alcohol preference and hypermotility during the withdrawal period by comparison with chronically alcoh...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Nicotine increases microdialysate brain amino acid concentrations and induces conditioned place preference
Description :
The action of nicotine on the nicotinic receptor-mediated release of inhibitory and excitatory acids in the nucleus accumbens, NAC, of freely moving rats was studied in order to clarify their effects' on reinforcing behavior as estimated by conditioned place preference (CPP). Using the technique of ...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Ethanol but not acetaldehyde induced changes in brain taurine: a microdialysis study
Description :
Research has suggested that catalase plays a role in mediating ethanol's psychopharmacological effects. Catalase is an enzyme that oxidizes ethanol to acetaldehyde. It has been reported that when catalase activity is reduced by 3-amino-1,2,4-triazole (AT), rats reduce their intake and preference for...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Taurine concentration in the brain and in the plasma following intraperitoneal injections.
Description :
Summary.The effect of different taurine doses (0.050, 0.125, 0.250, 0.500 and 1.000 g/kg) administered intraperitoneally to Wistar rats was studied in both the plasma and the hippocampal microdialysate content.The samples were analyzed by reverse phased HPLC for the microdialysate samples and by HPL...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Functional characteristics of TauA binding protein from TauABC Escherichia coli system.
Description :
Although TauA shares few common characteristics with other known periplasmic binding protein, TauA is a putative periplasmic binding protein, part of tauABCD gene cluster involved in sulfonate transport in sulphate starvation condition. This protein was expressed in E. coli BL 21 and purified before...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Adrenalectomy prevents the development of alcohol preference in male rats
Description :
By forcing adrenalectomized (ADX) and sham-operated (SHAM) rats to chronically drink ethanol by mean of presentation of only one drinking bottle containing 10% ethanol, no differences occurred between both groups. ADX and SHAM rats were then exposed to chronic alcoholization using an inhalation proc...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Acamprosate decreases the hypermotility during repeated ethanol withdrawal.
Description :
One of the known behavioral actions of acamprosate is to prevent relapse in weaned alcoholics. However, the mechanism underlying this effect remains unclear. In this study, the motility of Wistar male rats, which were either alcoholized by ethanol inhalation or simultaneously alcoholized and treated...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English