Results
author = "De Witte, Philippe"
Alcohol-non-preferring Sardinian rats exhibit a higher ethanol-induced taurine increase compared to alcohol-preferring Sardinian rats: a microdialysis study
Description :
It is well known that ethanol injections induce increases in the extracellular taurine concentration from various rat brain regions. Furthermore, recent studies have shown that taurine supplementation modulates the ethanol reinforcing effects in a place conditioning experiment. However, it is unknow...
Repository :
ORBi (University of Liège)
Language(s) :
English
Changes in the amygdala amino acid microdialysate after conditioning with a cue associated with ethanol
Description :
The excitatory amino acid neurotransmission within the amygdala has been implicated in learning associations between external stimuli and intrinsic reward values such that it may play a key role in conditioned drug effects. In the present studies, the responses of the excitatory amino acids, asparta...
Repository :
ORBi (University of Liège)
Language(s) :
English
Production of reactive oxygen species following acute ethanol or acetaldehyde and its reduction by acamprosate in chronically alcoholized rats.
Description :
The salicylate trap method, combined with microdialysis, has been used to validate whether reactive oxygen species, particularly hydroxyl radicals, ((*)OH), are generated in the hippocampus of male Wistar rats after acute intraperitoneal administration of either ethanol, 2 and 3 g/kg, or acetaldehyd...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Nicotine-induced changes of glutamate and arginine in naive and chronically alcoholized rats: an in vivo microdialysis study.
Description :
The effects of nicotine, when administered either acutely or chronically, at doses of 0.15, 0.3 or 0.6 mg/kg, on the release of glutamate and arginine in the rat nucleus accumbens have been studied in microdialysis experiments. Glutamate release significantly increased after acute nicotine injection...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Role of acetaldehyde in ethanol-induced conditioned taste aversion in rats
Description :
Rationale: In spite of many recent studies on the effects of acetaldehyde, it is still unclear whether acetaldehyde mediates the reinforcing and/or aversive effects of ethanol. Objectives: The present study reexamined the role of acetaldehyde in ethanol-induced conditioned taste aversion (CTA). A fi...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Changes in the amygdala amino acid microdialysate after conditioning with a cue associated with ethanol
Description :
Excitatory amino acid neurotransmission within the amygdala has been implicated in learning associations between external stimuli and intrinsic reward values, such that it may play a key role in conditioned drug effects. In the present studies, the responses of the excitatory amino acids, aspartate ...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Taurine increases in the nucleus accumbens microdialysate after acute ethanol administration to naive and chronically alcoholised rats
Description :
The extracellular changes of amino acids (glutamate, taurine and GABA) in the nucleus accumbens of freely moving rats were estimated using the microdialysis technique following acute and chronic ethanol injections (1, 2, and 3 g/kg body weight). Compared to baseline values, taurine increased by 154%...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Imbalance between neuroexcitatory and neuroinhibitory amino acids causes craving for ethanol
Author(s) :
De Witte, Philippe
,
Conference on Crossing Boundaries - Implications of Advances in Basic Sciences for the Management of Addiction
Description :
Long-term exposure to ethanol leads to an imbalance in different excitatory and inhibitory amino acids. When ethanol consumption is reduced or completely stopped, these imbalances in different amino acids and neurotransmitters are behaviorally expressed in the form of ethanol withdrawal. Glutamate, ...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Oral taurine supplementation modulates ethanol-conditioned stimulus preference.
Description :
The present study investigated the possible modulatory action of oral taurine supplementation on the rewarding and aversive properties of low and high ethanol doses in male Wistar rats. A vinegar odor stimulus was daily paired with either ethanol (0.3 or 2.0 g/kg) or saline. In addition, half of the...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Changes in plasma taurine levels after different endurance events.
Author(s) :
Ward, Roberta J.
,
Francaux, Marc
,
Cuisinier, C
,
Sturbois, Xavier
,
De Witte, Philippe
Description :
The sulphonated amino acid taurine increased significantly in the plasma of trained athletes after three endurance exercises of different duration and intensity, a 90 min run on a treadmill at 75% of an individual's VO2 peak, a Marathon, 42.2 km and a 100 km run, by 19%, 77% and 36%, respectively. S...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English