Results
author = "Cuypers, Ann"
Induction of oxidative stress and antioxidative mechanisms in Phaseolus vulgaris after Cd application
Author(s) :
SMEETS, Karen
,
CUYPERS, Ann
,
Lambrechts, A
,
SEMANE, Brahim
,
Hoet, P
,
Van Laere, A
,
VANGRONSVELD, Jaco
Description :
Oxidative stress has been shown to be of great importance in the toxicity of several metals (copper, zinc,...). In this study, the relationship of cadmium phytotoxicity and antioxidative reactions in bean (Phaseolus vulgaris L.) plants was investigated. Eleven-day-old seedlings were exposed to an en...
Repository :
Document Server@UHasselt
Language(s) :
English
Exposing mice to low Cd doses triggers a biphasic oxidative stress response in the kidney: a role for Prdx2 and Nox4?
Author(s) :
VAN KERKHOVE, Emmy
,
CUYPERS, Ann
,
MARINGWA, John
,
Horemans, Nele
,
LAMBRICHTS, Ivo
,
THIJSSEN, Sandy
Description :
In previous studies exposing animals to Cd caused oxidative stress and kidney damage. Mostly high doses were applied, often by injection. In the present study mice were exposed up to 23 weeks to low Cd concentrations (10 and 100 mg CdCl2/l) in the drinking water.
Antioxidant gene expression levels...
Repository :
Document Server@UHasselt
Language(s) :
English
Normalisation of real-time RT-PCR gene expression measurements in Arabidopsis thaliana exposed to increased metal concentrations
Author(s) :
REMANS, Tony
,
SMEETS, Karen
,
OPDENAKKER, Kelly
,
MATHIJSEN, Dennis
,
VANGRONSVELD, Jaco
,
CUYPERS, Ann
Description :
Accurate quantification by real-time RT-PCR relies on normalisation of the measured gene expression data. Normalisation with multiple reference genes is becoming the standard, but the best reference genes for gene expression studies within one organism may depend on the applied treatments or...
Repository :
Document Server@UHasselt
Language(s) :
English
The combined effect of uranium and gamma radiation on biological responses and oxidative stress induced in Arabidopsis thaliana
Author(s) :
VANHOUDT, Nathalie
,
Vandenhove, Hildegarde
,
Horemans, Nele
,
Wannijn, Jean
,
Van Hees, May
,
VANGRONSVELD, Jaco
,
CUYPERS, Ann
Description :
Uranium never occurs as a single pollutant in the environment, but always in combination with other stressors such as ionizing radiation. As effects induced by multiple contaminants can differ markedly from the effects induced by the individual stressors, this multiple pollution context should not b...
Repository :
Document Server@UHasselt
Language(s) :
English
Study of oxidative stress related responses induced in Arabidopsis thaliana following mixed exposure to uranium and cadmium
Author(s) :
VANHOUDT, Nathalie
,
Vandenhove, Hildegarde
,
Horemans, Nele
,
Wannijn, Jean
,
Bujanic, Andelko
,
VANGRONSVELD, Jaco
Description :
In this study, toxicity effects in plants of uranium in a binary pollution condition were investigated by studying biological responses and unraveling oxidative stress related mechanisms in Arabidopsis thaliana seedlings, grown on hydroponics and exposed for 3 days to 10 mu M uranium in combination ...
Repository :
Document Server@UHasselt
Language(s) :
English
Decreased placental mitochondrial DNA-content in response to air pollution during in utero life
Author(s) :
Janssen, Bram
,
Pieters, Nicky
,
Munters, Elke
,
Smeets, Karen
,
Cuypers, Ann
,
Penders, Joris
,
Vangronsveld, Jaco
,
Gyselaers, Wilfried
Description :
Recent studies have emphasized the importance of PM, and its associated metal components, in the formation of reactive oxygen species (ROS) and inflammation. Mitochondria are the major intracellular sources and primary targets of ROS. Mitochondrial DNA (mtDNA) is particularly vulnerable to ROS-induc...
Repository :
Document Server@UHasselt
Language(s) :
English
Reference genes for qPCR assays in toxic metal and salinity stress in two flatworm model organisms
Author(s) :
PLUSQUIN, Michelle
,
DEGHESELLE, Olivier
,
CUYPERS, Ann
,
GEERDENS, Ellen
,
VAN ROTEN, Andromeda
,
ARTOIS, Tom
,
SMEETS, Karen
Description :
The flatworm species Schmidtea mediterranea
and Macrostomum lignano have become new and innovative model organisms in stem cell, regeneration and tissue
homeostasis research. Because of their unique stem cell
system, (lab) technical advantages and their phylogenetic
position within the Metazoa, they ...
Repository :
Document Server@UHasselt
Language(s) :
English
Understanding the development of roots exposed to contaminants and the potential of plant-associated bacteria for optimization of growth
Author(s) :
Remans, Tony
,
Thijs, Sofie
,
Truyens, Sascha
,
Weyens, Nele
,
Schellingen, Kerim
,
Keunen, Els
,
Gielen, Heidi
,
Cuypers, Ann
Description :
Plant responses to the toxic effects of soil contaminants, such as excess metals or organic substances, have been studied mainly at physiological, biochemical and molecular levels, but the influence on root system architecture has received little attention. Nevertheless, the precise position, morpho...
Repository :
Document Server@UHasselt
Language(s) :
English
Exposure of Arabidopsis thaliana to excess Zn reveals a Zn-specific oxidative stress signature
Author(s) :
Remans, Tony
,
Opdenakker, Kelly
,
Guisez, Yves
,
Carleer, Robert
,
Schat, Henk
,
Vangronsveld, Jaco
,
Cuypers, Ann
Description :
Zinc (Zn) is an essential micronutrient for plants, but accumulation of excess Zn causes oxidative stress, even though the element is not redox-active. An oxidative stress signature, consisting of multiple oxidative stress related parameters, is indicative of disturbance of redox homeostasis and sig...
Repository :
Document Server@UHasselt
Language(s) :
English
House dust as possible route of environmental exposure to cadmium and lead in the adult general population
Author(s) :
Hogervorst, Janneke
,
PLUSQUIN, Michelle
,
VANGRONSVELD, Jaco
,
Nawrot, Tim
,
CUYPERS, Ann
,
Van Hecke, Etienne
,
Roels, Harry
Description :
Contaminated soil particles and food are established routes of exposure. We investigated the relations between biomarkers of exposure to cadmium and lead, and the metal loading rates in house dust in the adult residents of an area with a soil cadmium concentration of >= 3 mg/kg (n = 268) and a refer...
Repository :
Document Server@UHasselt
Language(s) :
English