flag flag  

Search all repositories
add criteria
Close advanced options Search for

 

Enter more search criteria
Publication Date
     
From
To
Document Language
Document Type
Repositories
New Search Save Search Refine Search
Results
author = "Curk, Tomaz"
1 2 3 4 > >>

Found 32 documents, displaying page 1 of 4

Computational approaches for gene network discovery

Author(s) : Curk, Tomaž
Description : This dissertation proposes a set of computational methods for inference of gene networks from heterogeneous data sources. These methods address problems of function prediction using different computational phenotypes, methods for the analysis of gene regulatory regions, and methods for decomposition...
Repository : ePrints.FRI - Fakulteta za računalništvo in informatiko, Univerza v Ljubljani
Language(s) : Undetermined

SNPsyn: detection and exploration of SNP-SNP interactions

Author(s) : Curk, Tomaz , Rot, Gregor , Zupan, Blaz
Description : SNPsyn (http://snpsyn.biolab.si) is an interactive software tool for the discovery of synergistic pairs of single nucleotide polymorphisms (SNPs) from large genome-wide case-control association studies (GWAS) data on complex diseases. Synergy among SNPs is estimated using an information-theoretic ap...
Repository : ePrints.FRI - Fakulteta za računalništvo in informatiko, Univerza v Ljubljani
Language(s) : Undetermined

SNPsyn: detection and exploration of SNP–SNP interactions

Author(s) : Curk, Tomaz , Rot, Gregor , Zupan, Blaz
Description : SNPsyn (http://snpsyn.biolab.si) is an interactive software tool for the discovery of synergistic pairs of single nucleotide polymorphisms (SNPs) from large genome-wide case-control association studies (GWAS) data on complex diseases. Synergy among SNPs is estimated using an information-theoretic ap...
Repository : Europe PubMed Central
Language(s) : English

Does replication groups scoring reduce false positive rate in SNP interaction discovery?

Author(s) : Toplak Marko , Curk Tomaz , Demsar Janez , Zupan Blaz
Description :

Abstract

Background

Computational methods that infer single nucleotide polymorphism (SNP) interactions from phenotype data may uncover new biological mechanisms in non-Mendelian diseases. However, practical aspects of such analysis face many problems. Present experimental studies ty...

Repository : DOAJ-Articles
Language(s) : English

Does replication groups scoring reduce false positive rate in SNP interaction discovery?

Author(s) : Toplak, Marko , Curk, Tomaz , Demsar, Janez , Zupan, Blaz
Description : BACKGROUNG. Computational methods that infer single nucleotide polymorphism (SNP) interactions from phenotype data may uncover new biological mechanisms in non-Mendelian diseases. However, practical aspects of such analysis face many problems. Present experimental studies typically use SNP arrays wi...
Repository : ePrints.FRI - Fakulteta za računalništvo in informatiko, Univerza v Ljubljani
Language(s) : Undetermined

Inference of the Molecular Mechanism of Action from Genetic Interaction and Gene Expression Data

Author(s) : Mattiazzi, Mojca , Curk, Tomaz , Krizaj, Igor , Zupan, Blaz , Petrovic, Uros
Description : Inference of new and useful hypotheses from heterogeneous sources of genome-scale experimental data requires new computational methods that can integrate different types of data. Gene expression and genetic interaction data are two most informative data types, each allowing the identification of gen...
Repository : ePrints.FRI - Fakulteta za računalništvo in informatiko, Univerza v Ljubljani
Language(s) : Undetermined

VizRank: Finding Informative Data Projections in Functional Genomics by Machine Learning

Author(s) : Leban, Gregor , Bratko, Ivan , Petrovič, Uroš , Curk, Tomaž , Zupan, Blaz
Description : VizRank is a tool that finds interesting two-dimensional projections of class-labeled data. When applied to multi-dimensional functional genomics data sets, VizRank can systematically find relevant biological patterns.
Repository : ePrints.FRI - Fakulteta za računalništvo in informatiko, Univerza v Ljubljani
Language(s) : Undetermined

Rule-based clustering for gene promoter structure discovery

Author(s) : Curk, Tomaz , Petrovic, Uros , Shaulsky, Gad , Zupan, Blaz
Description : BACKGROUND: The genetic cellular response to internal and external changes is determined by the sequence and structure of gene-regulatory promoter regions. OBJECTIVES: Using data on gene-regulatory elements (i.e., either putative or known transcription factor binding sites) and data on gene expressi...
Repository : ePrints.FRI - Fakulteta za računalništvo in informatiko, Univerza v Ljubljani
Language(s) : Undetermined

Does replication groups scoring reduce false positive rate in SNP interaction discovery?

Author(s) : Toplak, Marko , Curk, Tomaz , Demsar, Janez , Zupan, Blaz
Description :
Repository : Europe PubMed Central
Language(s) : English

dictyExpress: a Dictyostelium discoideum gene expression database with an explorative data analysis web-based interface

Author(s) : Rot Gregor , Parikh Anup , Curk Tomaz , Kuspa Adam , Shaulsky Gad , Zupan Blaz
Description :

Abstract

Background

Bioinformatics often leverages on recent advancements in computer science to support biologists in their scientific discovery process. Such efforts include the development of easy-to-use web interfaces to biomedical databases. Recent advancements in interactive w...

Repository : DOAJ-Articles
Language(s) : English
1 2 3 4 > >>

Found 32 documents, displaying page 1 of 4