Results
author = "Colin, M."
Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression
Author(s) :
Hersperger, Adam R.
,
Martin, Jeffrey N.
,
Shin, Lucy Y.
,
Sheth, Prameet M.
,
Kovacs, Colin M.
,
Cosma, Gabriela L.
Description :
Recent data suggest that CD8+ T-cell effector activity is an important component in the control of HIV replication in elite controllers (ECs). One critical element of CD8+ T-cell effector function and differentiation is the T-box transcription factor T-bet. In the present study, we assessed T-bet ex...
Repository :
Europe PubMed Central
Language(s) :
English
Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions
Author(s) :
Saha, Krishanu
,
Mei, Ying
,
Reisterer, Colin M.
,
Pyzocha, Neena Kenton
,
Yang, Jing
,
Muffat, Julien
,
Davies, Martyn C.
Description :
The current gold standard for the culture of human pluripotent stem cells requires the use of a feeder layer of cells. Here, we develop a spatially defined culture system based on UV/ozone radiation modification of typical cell culture plastics to define a favorable surface environment for human plu...
Repository :
Europe PubMed Central
Language(s) :
English
Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death
Author(s) :
Arif, Sefina
,
Moore, Fabrice
,
Marks, Katherine
,
Bouckenooghe, Thomas
,
Dayan, Colin M.
,
Planas, Raquel
,
Vives-Pi, Marta
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Achieved Levels of HbA1c and Likelihood of Hospital Admission in People With Type 1 Diabetes in the Scottish Population: A study from the Scottish Diabetes Research Network Epidemiology Group
Author(s) :
Govan, Lindsay
,
Wu, Olivia
,
Briggs, Andrew
,
Colhoun, Helen M.
,
Fischbacher, Colin M.
,
Leese, Graham P.
,
McKnight, John A.
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Widespread Triploidy in Western North American Aspen (Populus tremuloides)
Author(s) :
Mock, Karen E.
,
Callahan, Colin M.
,
Islam-Faridi, M. Nurul
,
Shaw, John D.
,
Rai, Hardeep S.
,
Sanderson, Stewart C.
Description :
We document high rates of triploidy in aspen (Populus tremuloides) across the western USA (up to 69% of genets), and ask whether the incidence of triploidy across the species range corresponds with latitude, glacial history (as has been documented in other species), climate, or regional variance in ...
Repository :
Europe PubMed Central
Language(s) :
English
Impact of HIV on Cell Survival and Antiviral Activity of Plasmacytoid Dendritic Cells
Author(s) :
Meyers, Jennifer Hartt
,
Justement, J. Shawn
,
Hallahan, Claire W.
,
Blair, Eric T.
,
Sun, Yongming A.
,
O'Shea, M. Angeline
Description :
Plasmacytoid dendritic cells (pDCs) are important mediators of innate immunity that act mainly through secretion of interferon (IFN)-α. Previous studies have found that these cells can suppress HIV in vitro; additionally, pDCs have been shown to be severely reduced in the peripheral blood of HIV-inf...
Repository :
Europe PubMed Central
Language(s) :
English
An Auditory Go/No-Go Study of Event-Related Potentials in Children with Fetal Alcohol Spectrum Disorders
Author(s) :
Steinmann, Tobias P.
,
Andrew, Colin M.
,
Thomsen, Carsten E.
,
Kjær, Troels W.
,
Meintjes, Ernesta M.
,
Molteno, Christopher D.
Description :
Abstract—In this study event-related potentials (ERPs) were
used to investigate the effects of prenatal alcohol exposure on
response inhibition identified during task performance. ERPs
were recorded during a auditory Go/No Go task in two groups
of children with mean age of 12:8years (11years to 14:7...
Repository :
ORBIT The DTU Research Database
Language(s) :
English
La girolline, nouvelle substance antitumorale extraite de l'éponge, Pseudaxinyssa cantharella n. sp. (Axinellidae)
Author(s) :
Ahond, A.
,
Bedoya Zurita, M.
,
Colin, M.
,
Fizames, C.
,
Laboute, Pierre
,
Lavelle, F.
,
Laurent, Dominique
,
Poupat, C.
Description :
Une nouvelle substance antitumorale a été isolée d'une Eponge néo-calédonienne, #Pseudaxinyssa cantharella$. Sa structure a été établie à l'aide de ses caractéristiques spectrales et par préparation de dérivés sélectivement substitués. (Résumé d'auteur)
Repository :
Horizon / Pleins textes
Language(s) :
French
Cathepsin L1, the Major Protease Involved in Liver Fluke (Fasciola hepatica) Virulence
Author(s) :
Collins, Peter R.
,
Stack, Colin M.
,
O'Neill, Sandra M.
,
Doyle, Sean
,
Ryan, Thecla
,
Brennan, Gerard P.
,
Mousley, Angela
Description :
The secretion and activation of the major cathepsin
L1 cysteine protease involved in the virulence of the
helminth pathogen Fasciola hepatica was investigated.
Only the fully processed and active mature enzyme can
be detected in medium in which adult F. hepatica are
cultured. However, immunocytochem...
Repository :
NUI Maynooth ePrints and eTheses Archive
Language(s) :
Undetermined
Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions
Author(s) :
Saha, Krishanu
,
Mei, Ying
,
Reisterer, Colin M.
,
Pyzocha, Neena Kenton
,
Yang, Jing
,
Muffat, Julien
,
Davies, Martyn C.
Description :
The current gold standard for the culture of human pluripotent stem cells requires the use of a feeder layer of cells. Here, we develop a spatially defined culture system based on UV/ozone radiation modification of typical cell culture plastics to define a favorable surface environment for human plu...
Repository :
DSpace@MIT - MIT's online institutional repository
Language(s) :
English