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author = "Cohn, Melvin"

Found 13 documents, displaying page 1 of 2

What roles do regulatory T cells play in the control of the adaptive immune response?

Author(s) : Cohn, Melvin
Description : The immune system, like many systems responsive to specific stimuli, requires feedback regulation. The key regulatory element determining antigen-specific responsiveness is the effector T helper. As the response tends to overshoot, a feedback control of the magnitude of the response is critical to a...
Repository : Europe PubMed Central
Language(s) : English

THE USE OF BACTERIAL LIPOPOLYSACCHARIDES TO SHOW THAT TWO SIGNALS ARE REQUIRED FOR THE INDUCTION OF ANTIBODY SYNTHESIS

Description : Evidence is presented that antigen-sensitive cells require two signals for induction. Normally these two signals are delivered to the cell via the recognition of two determinants on the immunogen: the first the receptor on the antigen-sensitive cell, and the second by the cooperating cell system. T...
Repository : Europe PubMed Central
Language(s) : English

Leukemia Viruses Associated with Mouse Myeloma Cells*

Description : Myeloma cells derived from BALB/c and C3H mice show evidence of infection by a murine leumemia virus. The immunoglobulin-producing myelomas secrete an RNA-containing virus with a density of 1.20 to 1.22 gm/cm3. RNA with a sedimentation coefficient of 74 S in 0.1 M sodium sodium chloride has been iso...
Repository : Europe PubMed Central
Language(s) : English

In vitro DIFFERENTIATION OF A MOUSE NEUROBLASTOMA*

Description : Mouse tumor C1300 has been established in tissue culture. The cells have a round cell morphology in both the subcutaneous tumor and in suspension culture. However, when given a surface on which to attach, they send out processes up to 3 mm in length and assume the morphology of mature neurons. The a...
Repository : Europe PubMed Central
Language(s) : English

A NEW MOUSE IMMUNOGLOBULIN: IGG3

Description : A new subclass of mouse IgG for which we propose the name IgG3 has been shown to have a mol wt of 150,000 consistent with an L2H2 structure, and is present in normal mouse serum at a concentration of 0.1–0.2 mg/ml. Its molecular weight, low carbohydrate content, glycopeptide analysis, and C-termina...
Repository : Europe PubMed Central
Language(s) : English

Found 13 documents, displaying page 1 of 2