Results
author = "Casteel, Darren E"
A cysteine-rich LIM-only protein mediates regulation of smooth muscle-specific gene expression by cGMP-dependent protein kinase
Description :
Repository :
DOAJ-Articles
Language(s) :
English
Src activation by cGMP/PKG II in osteoblasts: characterization of a mechano-sensitive signalling complex
Author(s) :
Rangaswami Hema
,
Schwappacher Raphaela
,
Marathe Nisha
,
Casteel Darren E
,
Haas Bodo
,
Pfeifer Alexander
,
Shattil Sanford
Description :
Repository :
DOAJ-Articles
Language(s) :
English
Synergism between Calcium and Cyclic GMP in Cyclic AMP Response Element-Dependent Transcriptional Regulation Requires Cooperation between CREB and C/EBP-β
Author(s) :
Chen, Yongchang
,
Zhuang, Shunhui
,
Cassenaer, Stijn
,
Casteel, Darren E.
,
Gudi, Tanima
,
Boss, Gerry R.
,
Pilz, Renate B.
Description :
Calcium induces transcriptional activation of the fos promoter by activation of the cyclic AMP response element (CRE)-binding protein (CREB), and in some cells its effect is enhanced synergistically by cyclic GMP (cGMP) through an unknown mechanism. We observed calcium-cGMP synergism in neuronal and...
Repository :
Europe PubMed Central
Language(s) :
English
A Crystal Structure of the Cyclic GMP-dependent Protein Kinase Iβ Dimerization/Docking Domain Reveals Molecular Details of Isoform-specific Anchoring*
Author(s) :
Casteel, Darren E.
,
Smith-Nguyen, Eric V.
,
Sankaran, Banumathi
,
Roh, Sung H.
,
Pilz, Renate B.
,
Kim, Choel
Description :
Cyclic GMP-dependent protein kinase (PKG) is a key mediator of the nitric oxide/cGMP signaling pathway and plays a central role in regulating cardiovascular and neuronal functions. The N-terminal ∼50 amino acids of the kinase are required for homodimerization and association with isoform-specific PK...
Repository :
Europe PubMed Central
Language(s) :
English
The first crystal structure of cyclic GMP-dependent protein kinase Iβ dimerization/docking domain reveals molecular details of isoform-specific anchoring
Author(s) :
Casteel Darren E
,
Smith-Nguyen Eric V
,
Sankaran Banumathi
,
Spraggon Glen
,
Hampton Eric N
,
Pilz Renate B
,
Taylor Susan S
Description :
Repository :
DOAJ-Articles
Language(s) :
English
The crystal structures of PKG Iβ (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding
Author(s) :
Kim Jeong
,
Casteel Darren E
,
Huang Gilbert
,
Kwon Taek
,
Ren Ronnie
,
Zwart Peter
,
Headd Jeffrey J
,
Brown Nicholas
,
Chow Dar-Chone
Description :
Repository :
DOAJ-Articles
Language(s) :
English
A DNA Polymerase-α·Primase Cofactor with Homology to Replication Protein A-32 Regulates DNA Replication in Mammalian Cells*S⃞
Author(s) :
Casteel, Darren E.
,
Zhuang, Shunhui
,
Zeng, Ying
,
Perrino, Fred W.
,
Boss, Gerry R.
,
Goulian, Mehran
,
Pilz, Renate B.
Description :
α-Accessory factor (AAF) stimulates the activity of DNA
polymerase-α·primase, the only enzyme known to initiate DNA
replication in eukaryotic cells (Goulian, M., Heard, C. J.,
and Grimm, S. L. (1990) J. Biol. Chem.265
,13221
-132302165497). We purified the AAF
heterodimer composed of 44- and 132-kDa...
Repository :
Europe PubMed Central
Language(s) :
English
The first crystal structure of cyclic GMP-dependent protein kinase Iβ dimerization/docking domain reveals molecular details of isoform-specific anchoring
Author(s) :
Casteel, Darren E
,
Smith-Nguyen, Eric V
,
Sankaran, Banumathi
,
Spraggon, Glen
,
Hampton, Eric N
,
Pilz, Renate B
,
Taylor, Susan S
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Src activation by cGMP/PKG II in osteoblasts: characterization of a mechano-sensitive signalling complex
Author(s) :
Rangaswami, Hema
,
Schwappacher, Raphaela
,
Marathe, Nisha
,
Casteel, Darren E
,
Haas, Bodo
,
Pfeifer, Alexander
,
Shattil, Sanford
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Co-Crystal Structures of PKG Iβ (92–227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding
Author(s) :
Kim, Jeong Joo
,
Casteel, Darren E.
,
Huang, Gilbert
,
Kwon, Taek Hun
,
Ren, Ronnie Kuo
,
Zwart, Peter
,
Headd, Jeffrey J.
Description :
Repository :
Europe PubMed Central
Language(s) :
English